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π
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Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers
7 auth.
Isaac B. Hilton,
A. D'Ippolito,
Christopher M. Vockley,
P. Thakore,
G. Crawford,
Timothy E. Reddy,
...
C. Gersbach
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10 |
2015 |
10
π
|
|
π
|
Architecture of the human regulatory network derived from ENCODE data
55 auth.
M. Gerstein,
A. Kundaje,
M. Hariharan,
S. Landt,
Koon-Kiu Yan,
Chao Cheng,
X. Mu,
Ekta Khurana,
J. Rozowsky,
Roger P. Alexander,
Martin Renqiang Min,
P. Alves,
A. Abyzov,
Nicholas J. Addleman,
N. Bhardwaj,
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A. Boyle,
Philip Cayting,
Alexandra E. Charos,
David Z. Chen,
Declan Clarke,
Catharine L. Eastman,
G. Euskirchen,
S. Frietze,
Yao Fu,
Jason Gertz,
Fabian Grubert,
A. Harmanci,
Preti Jain,
Maya Kasowski,
P. Lacroute,
Jing Leng,
Jin Lian,
Hannah Monahan,
H. OβGeen,
Z. Ouyang,
E. Partridge,
Dorrelyn Patacsil,
Florencia Pauli,
D. Raha,
L. RamΓrez,
Timothy E. Reddy,
Brian D. Reed,
Minyi Shi,
T. Slifer,
Jing Wang,
Linfeng Wu,
Xinqiong Yang,
Kevin Y. Yip,
Gili Zilberman-Schapira,
S. Batzoglou,
A. Sidow,
P. Farnham,
R. Myers,
S. Weissman,
Michael P. Snyder
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10 |
2012 |
10
π
|
|
π
|
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
15 auth.
P. Perez-Pinera,
D. D. Kocak,
Christopher M. Vockley,
Andrew F Adler,
Ami M. Kabadi,
Lauren R. Polstein,
P. Thakore,
Katherine A. Glass,
David G. Ousterout,
Kam W. Leong,
...
Kam W. Leong,
F. Guilak,
G. Crawford,
Timothy E. Reddy,
C. Gersbach
|
10 |
2013 |
10
π
|
|
π
|
A User's Guide to the Encyclopedia of DNA Elements (ENCODE)
314 auth.
R. Myers,
J. Stamatoyannopoulos,
M. Snyder,
I. Dunham,
R. Hardison,
B. Bernstein,
T. Gingeras,
W. Kent,
E. Birney,
B. Wold,
G. Crawford,
C. Epstein,
N. Shoresh,
J. Ernst,
T. Mikkelsen,
...
Pouya Kheradpour,
Xiaolan Zhang,
Li Wang,
Robbyn Issner,
Michael J. Coyne,
Timothy J. Durham,
Manching Ku,
Thanh Truong,
L. D. Ward,
Robert C. Altshuler,
Michael F. Lin,
Manolis Kellis,
Carrie A. Davis,
P. Kapranov,
A. Dobin,
C. Zaleski,
F. Schlesinger,
P. Batut,
S. Chakrabortty,
Sonali Jha,
Wei Lin,
J. Drenkow,
Huaien Wang,
K. Bell,
I. Bell,
Hui Gao,
E. Dumais,
Jacqueline Dumais,
S. Antonarakis,
C. Ucla,
C. Borel,
R. GuigΓ³,
S. Djebali,
Julien Lagarde,
C. Kingswood,
Paolo Ribeca,
M. Sammeth,
T. Alioto,
A. Merkel,
Hagen U. Tilgner,
Piero Carninci,
Y. Hayashizaki,
T. Lassmann,
Hazuki Takahashi,
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G. Hannon,
Katalin Fejes,
Jonathan Preall,
Assaf Gordon,
V. Sotirova,
A. Reymond,
C. Howald,
Emilie AΓ―t Yahya Graison,
Jacqueline Chrast,
Y. Ruan,
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Atif Shahab,
W. Poh,
Chia-Lin Wei,
T. Furey,
A. Boyle,
Nathan C. Sheffield,
Lingyun Song,
Yoichiro Shibata,
T. Vales,
D. Winter,
Zhancheng Zhang,
D. London,
Tian-yuan Wang,
Damian Keefe,
V. Iyer,
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Zheng Liu,
Anna M. Battenhouse,
A. Bhinge,
J. Lieb,
L. Grasfeder,
Kimberly A. Showers,
P. Giresi,
Seul K.C. Kim,
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Timothy E. Reddy,
Jason Gertz,
E. Partridge,
Preti Jain,
Rebekka O. Sprouse,
A. Bansal,
Barbara N. Pusey,
M. Muratet,
K. Varley,
K. Bowling,
Kimberly M. Newberry,
Amy S. Nesmith,
Jason A. Dilocker,
S. Parker,
L. Waite,
Krista S. Thibeault,
Kevin Roberts,
D. Absher,
A. Mortazavi,
B. Williams,
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Diane Trout,
Brandon King,
Kenneth McCue,
Anthony Kirilusha,
Gilberto Desalvo,
Katherine Fisher,
Henry Amrhein,
S. Pepke,
J. Vielmetter,
G. Sherlock,
A. Sidow,
S. Batzoglou,
Rami Rauch,
A. Kundaje,
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E. Margulies,
Stephen C. J. Parker,
L. Elnitski,
E. Green,
T. Hubbard,
J. Harrow,
S. Searle,
F. Kokocinski,
B. Aken,
A. Frankish,
T. Hunt,
Gloria Despacio-Reyes,
M. Kay,
Gaurab Mukherjee,
A. Bignell,
Gary Saunders,
Veronika Boychenko,
M. Brent,
M. Baren,
Randall H. Brown,
M. Gerstein,
Ekta Khurana,
S. Balasubramanian,
Hugo Y. K. Lam,
Philip Cayting,
R. Robilotto,
Z. Lu,
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Andrea Tanzer,
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M. Mariotti,
D. Haussler,
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M. Diekhans,
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G. Euskirchen,
Fabian Grubert,
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Jin Lian,
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Youhan Xu,
Hannah Monahan,
Dorrelyn Patacsil,
T. Slifer,
Xinqiong Yang,
Alexandra E. Charos,
Brian D. Reed,
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Raymond K. Auerbach,
L. Habegger,
M. Hariharan,
J. Rozowsky,
A. Abyzov,
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10 |
2011 |
10
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|
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π
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Highly Specific Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements
9 auth.
P. Thakore,
A. D'Ippolito,
Lingyun Song,
Alexias Safi,
Nishkala Shivakumar,
Ami M. Kabadi,
...
Timothy E. Reddy,
G. Crawford,
C. Gersbach
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9 |
2015 |
9
π
|
|
π
|
Dynamic DNA methylation across diverse human cell lines and tissues
13 auth.
K. Varley,
Jason Gertz,
K. Bowling,
S. Parker,
Timothy E. Reddy,
Florencia Pauli-Behn,
M. Cross,
B. Williams,
J. Stamatoyannopoulos,
G. Crawford,
...
D. Absher,
B. Wold,
R. Myers
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9 |
2013 |
9
π
|
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π¦
|
Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation.
7 auth.
Timothy E. Reddy,
Florencia Pauli,
Rebekka O. Sprouse,
N. Neff,
Kimberly M. Newberry,
M. Garabedian,
...
R. Myers
|
9 |
2009 |
9
π¦
|
|
π
|
CRISPRβCas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
9 auth.
Tyler S. Klann,
Joshua B. Black,
M. Chellappan,
Alexias Safi,
Lingyun Song,
Isaac B. Hilton,
...
G. Crawford,
Timothy E. Reddy,
C. Gersbach
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8 |
2017 |
8
π
|
|
π
|
The PsychENCODE project
83 auth.
S. Akbarian,
Chunyu Liu,
J. Knowles,
F. Vaccarino,
P. Farnham,
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S. Dracheva,
D. Geschwind,
J. Mill,
A. Nairn,
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S. Weissman,
P. Sullivan,
M. State,
Z. Weng,
M. Peters,
K. White,
M. Gerstein,
Anahita Amiri,
Chris Armoskus,
A. Ashley-Koch,
Taejeong Bae,
A. Beckel-Mitchener,
B. Berman,
G. Coetzee,
Gianfilippo Coppola,
Nancy J Francoeur,
M. Fromer,
R. Gao,
Kay S. Grennan,
J. Herstein,
D. Kavanagh,
N. A. Ivanov,
Yan Jiang,
R. Kitchen,
A. Kozlenkov,
M. Kundakovic,
Mingfeng Li,
Zhen Li,
Shuang Liu,
L. Mangravite,
E. Mattei,
Eirene Markenscoff-Papadimitriou,
FΓ‘bio C. P. Navarro,
N. North,
L. Omberg,
David M. Panchision,
N. Parikshak,
Jeremie Poschmann,
A. Price,
Michael J. Purcaro,
Timothy E. Reddy,
P. Roussos,
S. Schreiner,
S. Scuderi,
R. Sebra,
M. Shibata,
Annie W Shieh,
Mario Ε karica,
V. Swarup,
Amber Thomas,
J. Tsuji,
H. Bakel,
Daifeng Wang,
Yongjun Wang,
Kai Wang,
Donna M. Werling,
A. Willsey,
Heather Witt,
H. Won,
Chloe C. Y. Wong,
G. Wray,
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Xuming Xu,
Lijing Yao,
G. Senthil,
T. Lehner,
P. Sklar,
N. Ε estan
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8 |
2015 |
8
π
|
|
π
|
Distinct properties of cell-type-specific and shared transcription factor binding sites.
10 auth.
Jason Gertz,
D. Savic,
K. Varley,
E. Partridge,
Alexias Safi,
Preti Jain,
...
G. Cooper,
Timothy E. Reddy,
G. Crawford,
R. Myers
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8 |
2013 |
8
π
|
|
π
|
Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation
9 auth.
Jason Gertz,
K. Varley,
Timothy E. Reddy,
K. Bowling,
Florencia Pauli,
S. Parker,
...
Katerina S. Kucera,
H. Willard,
R. Myers
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8 |
2011 |
8
π
|
|
π
|
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver.
15 auth.
Alayne L. Brunner,
David S. Johnson,
S. Kim,
Anton Valouev,
Timothy E. Reddy,
N. Neff,
Elizabeth Anton,
Catherine Medina,
Loan Nguyen,
E. Chiao,
...
C. Oyolu,
G. Schroth,
D. Absher,
J. Baker,
R. Myers
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8 |
2009 |
8
π
|
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π
|
Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells.
9 auth.
Joshua B. Black,
Andrew F Adler,
Hong-Gang Wang,
A. D'Ippolito,
Hunter A. Hutchinson,
Timothy E. Reddy,
...
G. Pitt,
K. Leong,
C. Gersbach
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7 |
2016 |
7
π
|
