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From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
11 auth.
A. Subramanian,
P. Tamayo,
V. Mootha,
Sayan Mukherjee,
B. Ebert,
Michael A. Gillette,
...
A. Paulovich,
S. Pomeroy,
T. Golub,
E. Lander,
J. Mesirov
|
15 |
2005 |
15
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MicroRNA expression profiles classify human cancers
14 auth.
Jun Lu,
G. Getz,
E. Miska,
Ezequiel Alvarez-Saavedra,
J. Lamb,
David Peck,
A. Sweet-Cordero,
B. Ebert,
Raymond H. Mak,
A. Ferrando,
...
J. Downing,
T. Jacks,
H. Horvitz,
T. Golub
|
13 |
2005 |
13
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PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
21 auth.
V. Mootha,
C. Lindgren,
K. Eriksson,
A. Subramanian,
S. Sihag,
J. Lehár,
P. Puigserver,
E. Carlsson,
M. Ridderstråle,
E. Laurila,
...
N. Houstis,
M. Daly,
N. Patterson,
J. Mesirov,
T. Golub,
P. Tamayo,
B. Spiegelman,
E. Lander,
J. Hirschhorn,
D. Altshuler,
L. Groop
|
12 |
2003 |
12
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The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
61 auth.
J. Barretina,
G. Caponigro,
Nicolas Stransky,
K. Venkatesan,
Adam A. Margolin,
Sungjoon Kim,
Christopher J. Wilson,
J. Lehár,
G. Kryukov,
D. Sonkin,
Anupama Reddy,
Manway Liu,
Lauren Murray,
M. Berger,
J. Monahan,
...
Paula Morais,
Jodi Meltzer,
A. Korejwa,
Judit Jané-Valbuena,
F. Mapa,
Joseph Thibault,
Eva Bric-Furlong,
Pichai Raman,
Aaron Shipway,
I. Engels,
Jill Cheng,
Guoying Yu,
Jianjun Yu,
Peter Aspesi,
Melanie de Silva,
Kalpana Jagtap,
Michael D. Jones,
Li R. Wang,
C. Hatton,
E. Palescandolo,
Supriya Gupta,
Scott Mahan,
C. Sougnez,
R. Onofrio,
T. Liefeld,
L. Macconaill,
W. Winckler,
Michael Reich,
Nanxin Li,
J. Mesirov,
S. Gabriel,
G. Getz,
K. Ardlie,
Vivien W. Chan,
V. Myer,
B. Weber,
Jeff Porter,
M. Warmuth,
P. Finan,
Jennifer L. Harris,
M. Meyerson,
T. Golub,
Michael P. Morrissey,
W. Sellers,
R. Schlegel,
L. Garraway
|
12 |
2012 |
12
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways
231 auth.
R. McLendon,
A. Friedman,
D. Bigner,
Erwin G. Van Meir,
D. Brat,
Gena M Mastrogianakis,
J. Olson,
T. Mikkelsen,
N. Lehman,
K. Aldape,
W. Yung,
O. Bogler,
J. Weinstein,
S. Vandenberg,
M. Berger,
...
M. Prados,
D. Muzny,
M. Morgan,
S. Scherer,
A. Sabo,
L. Nazareth,
L. Lewis,
O. Hall,
Yiming Zhu,
Yanru Ren,
Omar Alvi,
Jiqiang Yao,
A. Hawes,
S. Jhangiani,
G. Fowler,
A. Lucas,
C. Kovar,
Andrew Cree,
H. Dinh,
J. Santibanez,
Vandita Joshi,
M. Gonzalez-Garay,
Christopher A. Miller,
A. Milosavljevic,
L. Donehower,
D. Wheeler,
R. Gibbs,
K. Cibulskis,
C. Sougnez,
T. Fennell,
Scott Mahan,
Jane Wilkinson,
L. Ziaugra,
R. Onofrio,
Toby Bloom,
R. Nicol,
K. Ardlie,
J. Baldwin,
S. Gabriel,
E. Lander,
L. Ding,
R. Fulton,
M. McLellan,
J. Wallis,
D. Larson,
Xiaoqi Shi,
R. Abbott,
L. Fulton,
Ken Chen,
D. Koboldt,
M. Wendl,
R. Meyer,
Yuzhu Tang,
Ling Lin,
John R. Osborne,
Brian H. Dunford-Shore,
T. Miner,
K. Delehaunty,
C. Markovic,
Gary W. Swift,
W. Courtney,
C. Pohl,
S. Abbott,
Amy E. Hawkins,
Shin Leong,
C. Haipek,
Heather K. Schmidt,
M. Wiechert,
T. Vickery,
S. Scott,
D. Dooling,
A. Chinwalla,
G. Weinstock,
E. Mardis,
R. Wilson,
G. Getz,
W. Winckler,
R. Verhaak,
M. Lawrence,
Michael J. T. O’Kelly,
James Robinson,
Gabriele Alexe,
R. Beroukhim,
S. Carter,
Derek Y. Chiang,
Josh Gould,
Supriya Gupta,
Joshua M. Korn,
C. Mermel,
J. Mesirov,
S. Monti,
Huy L. Nguyen,
Melissa Parkin,
Michael Reich,
Nicolas Stransky,
B. Weir,
L. Garraway,
T. Golub,
M. Meyerson,
L. Chin,
A. Protopopov,
Jianhua Zhang,
I. Perna,
S. Aronson,
N. Sathiamoorthy,
Georgi Ren,
Jun Yao,
W. Wiedemeyer,
Hyun Soo Kim,
Won Kong Sek,
Yonghong Xiao,
I. Kohane,
J. Seidman,
P. Park,
R. Kucherlapati,
P. Laird,
L. Cope,
J. Herman,
D. Weisenberger,
F. Pan,
D. V. Berg,
L. V. Neste,
Mingyu Joo,
Kornel E. Schuebel,
S. Baylin,
D. Absher,
Jun Z. Li,
Audrey M. Southwick,
Shannon T. Brady,
A. Aggarwal,
Tisha Chung,
G. Sherlock,
J. Brooks,
R. Myers,
P. Spellman,
E. Purdom,
L. Jakkula,
A. Lapuk,
H. Marr,
S. Dorton,
Gi Choi Yoon,
Ju Han,
A. Ray,
V. Wang,
S. Durinck,
M. Robinson,
Nicholas J. Wang,
K. Vranizan,
V. Peng,
E. V. Name,
G. Fontenay,
J. Ngai,
J. Conboy,
B. Parvin,
H. Feiler,
T. Speed,
J. Gray,
C. Brennan,
N. Socci,
A. Olshen,
B. Taylor,
A. Lash,
N. Schultz,
B. Reva,
Yevgeniy Antipin,
Alexey Stukalov,
Benjamin E. Gross,
E. Cerami,
Qingqing Wei,
L. Qin,
V. Seshan,
L. Villafania,
Magali Cavatore,
L. Borsu,
A. Viale,
W. Gerald,
C. Sander,
M. Ladanyi,
C. Perou,
D. Hayes,
M. D. Topal,
K. Hoadley,
Yuan Qi,
S. Balu,
Yan Shi,
Junyuan Wu,
R. Penny,
M. Bittner,
T. Shelton,
E. Lenkiewicz,
S. Morris,
D. Beasley,
Sheri Sanders,
A. Kahn,
R. Sfeir,
Jessica Chen,
D. Nassau,
Larry Feng,
E. Hickey,
A. Barker,
D. Gerhard,
J. Vockley,
C. Compton,
J. Vaught,
P. Fielding,
M. Ferguson,
C. Schaefer,
Jinghui Zhang,
Subha Madhavan,
K. Buetow,
F. Collins,
P. Good,
M. Guyer,
B. Ozenberger,
Jane L. Peterson,
E. Thomson
|
12 |
2008 |
12
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The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
20 auth.
J. Lamb,
E. Crawford,
David Peck,
Joshua W. Modell,
Irene C. Blat,
Matthew J Wrobel,
Jim Lerner,
Jean-Philippe Brunet,
A. Subramanian,
K. Ross,
...
Michael Reich,
H. Hieronymus,
G. Wei,
S. Armstrong,
S. Haggarty,
P. Clemons,
Ru Wei,
S. Carr,
E. Lander,
T. Golub
|
12 |
2006 |
12
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The landscape of somatic copy-number alteration across human cancers
62 auth.
R. Beroukhim,
C. Mermel,
D. Porter,
G. Wei,
S. Raychaudhuri,
Jerry Donovan,
J. Barretina,
J. Boehm,
Jennifer Dobson,
M. Urashima,
Kevin T. Mc Henry,
Reid Pinchback,
A. Ligon,
Yoon-Jae Cho,
Leila Haery,
...
H. Greulich,
Michael Reich,
W. Winckler,
M. Lawrence,
B. Weir,
K. Tanaka,
Derek Y. Chiang,
A. Bass,
Alice T. Loo,
Carter Hoffman,
John R. Prensner,
T. Liefeld,
Qing Gao,
Derek W. Yecies,
S. Signoretti,
E. Maher,
F. Kaye,
H. Sasaki,
J. Tepper,
J. Fletcher,
J. Tabernero,
J. Baselga,
M. Tsao,
F. Demichelis,
M. Rubin,
P. Janne,
M. Daly,
C. Nucera,
R. Levine,
B. Ebert,
S. Gabriel,
A. Rustgi,
C. Antonescu,
M. Ladanyi,
A. Letai,
L. Garraway,
M. Loda,
D. Beer,
L. True,
A. Okamoto,
S. Pomeroy,
S. Singer,
T. Golub,
E. Lander,
G. Getz,
W. Sellers,
M. Meyerson
|
11 |
2010 |
11
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Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation.
8 auth.
P. Tamayo,
D. Slonim,
J. Mesirov,
Q. Zhu,
S. Kitareewan,
E. Dmitrovsky,
...
E. Lander,
T. Golub
|
11 |
1999 |
11
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🐜
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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
29 auth.
R. Levine,
M. Wadleigh,
J. Cools,
B. Ebert,
G. Wernig,
B. Huntly,
T. Boggon,
I. Wlodarska,
Jennifer J. Clark,
Sandra A. Moore,
Jennifer Adelsperger,
Sumin Koo,
Jeffrey C. Lee,
S. Gabriel,
T. Mercher,
...
A. D’Andrea,
S. Fröhling,
K. Döhner,
P. Marynen,
P. Vandenberghe,
R. Mesa,
A. Tefferi,
J. Griffin,
M. Eck,
W. Sellers,
M. Meyerson,
T. Golub,
Stephanie J. Lee,
D. Gilliland
|
11 |
2005 |
11
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Discovery and saturation analysis of cancer genes across 21 tumor types
9 auth.
M. Lawrence,
P. Stojanov,
C. Mermel,
L. Garraway,
T. Golub,
M. Meyerson,
...
S. Gabriel,
E. Lander,
G. Getz
|
11 |
2014 |
11
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🐜
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Gene expression correlates of clinical prostate cancer behavior.
15 auth.
Dinesh Singh,
P. Febbo,
K. Ross,
D. Jackson,
J. Manola,
C. Ladd,
P. Tamayo,
A. Renshaw,
A. D'Amico,
J. Richie,
...
E. Lander,
M. Loda,
P. Kantoff,
T. Golub,
W. Sellers
|
11 |
2002 |
11
🐜
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🐢
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A molecular signature of metastasis in primary solid tumors
Sridhar Ramaswamy,
K. Ross,
E. Lander,
T. Golub
|
11 |
2003 |
11
🐢
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|
🐢
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Prediction of central nervous system embryonal tumour outcome based on gene expression
25 auth.
S. Pomeroy,
P. Tamayo,
M. Gaasenbeek,
Lisa-Marie Sturla,
Michael Angelo,
M. Mclaughlin,
John Y. H. Kim,
L. Goumnerova,
P. Black,
C. Lau,
J. Allen,
D. Zagzag,
James M. Olson,
T. Curran,
C. Wetmore,
...
J. Biegel,
T. Poggio,
Shayan Mukherjee,
R. Rifkin,
A. Califano,
G. Stolovitzky,
D. Louis,
J. Mesirov,
E. Lander,
T. Golub
|
11 |
2002 |
11
🐢
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🐢
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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles
56 auth.
A. Subramanian,
Rajiv Narayan,
S. M. Corsello,
David Peck,
Ted E. Natoli,
Xiaodong Lu,
Joshua Gould,
John F. Davis,
Andrew A. Tubelli,
Jacob K. Asiedu,
D. L. Lahr,
J. Hirschman,
Zihan Liu,
M. Donahue,
Bina Julian,
...
Mariya Khan,
David Wadden,
Ian Smith,
Daniel Lam,
A. Liberzon,
Courtney Toder,
Mukta Bagul,
Marek Orzechowski,
Oana M. Enache,
F. Piccioni,
Sarah Johnson,
Nicholas J. Lyons,
A. Berger,
Alykhan F. Shamji,
Angela N. Brooks,
Anita Vrcic,
Corey Flynn,
Jacqueline Rosains,
D. Takeda,
R. Hu,
Desiree Davison,
J. Lamb,
K. Ardlie,
L. Hogstrom,
Peyton Greenside,
N. Gray,
P. Clemons,
S. Silver,
Xiaoyun Wu,
Wen-Ning Zhao,
Willis Read-Button,
Xiaohua Wu,
S. Haggarty,
L. Ronco,
J. Boehm,
S. Schreiber,
John G Doench,
Joshua A. Bittker,
D. Root,
Bang Wong,
T. Golub
|
11 |
2017 |
11
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🐢
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Copper induces cell death by targeting lipoylated TCA cycle proteins
18 auth.
Peter Tsvetkov,
S. Coy,
Boryana Petrova,
Margaret B. Dreishpoon,
A. Verma,
M. Abdusamad,
J. Rossen,
Lena M Joesch-Cohen,
Ranad Humeidi,
R. Spangler,
...
J. Eaton,
Evgeni M. Frenkel,
M. Kocak,
S. M. Corsello,
S. Lutsenko,
Naama Kanarek,
S. Santagata,
T. Golub
|
11 |
2022 |
11
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Next-generation characterization of the Cancer Cell Line Encyclopedia
68 auth.
M. Ghandi,
F. Huang,
Judit Jané-Valbuena,
G. Kryukov,
Christopher C. Lo,
E. McDonald,
J. Barretina,
Ellen T. Gelfand,
C. Bielski,
Haoxin Li,
K. Hu,
Alexander Y. Andreev-Drakhlin,
Jaegil Kim,
J. Hess,
B. Haas,
...
F. Aguet,
B. Weir,
M. Rothberg,
B. Paolella,
M. Lawrence,
Rehan Akbani,
Yiling Lu,
Hong L. Tiv,
P. Gokhale,
Antoine de Weck,
Ali Amin Mansour,
Coyin Oh,
J. Shih,
Kevin Hadi,
Yanay Rosen,
J. Bistline,
K. Venkatesan,
Anupama Reddy,
D. Sonkin,
Manway Liu,
J. Lehár,
Joshua M. Korn,
D. Porter,
Michael D. Jones,
J. Golji,
G. Caponigro,
Jordan E. Taylor,
C. Dunning,
Amanda L. Creech,
Allison C. Warren,
James M. McFarland,
Mahdi Zamanighomi,
A. Kauffmann,
Nicolas Stransky,
M. Imieliński,
Y. Maruvka,
A. Cherniack,
Aviad Tsherniak,
F. Vazquez,
Jacob D. Jaffe,
A. Lane,
D. Weinstock,
Cory M. Johannessen,
Michael P. Morrissey,
F. Stegmeier,
R. Schlegel,
W. Hahn,
G. Getz,
G. Mills,
J. Boehm,
T. Golub,
L. Garraway,
W. Sellers
|
11 |
2019 |
11
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