🐜
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A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models
21 auth.
Yiming Zhou,
Philip Castonguay,
Eriene-Heidi Sidhom,
A. Clark,
Moran Dvela-Levitt,
Sookyung Kim,
Jonas Sieber,
Nicolas Wieder,
J. Jung,
S. Andreeva,
...
Jana Reichardt,
F. Dubois,
S. Hoffmann,
J. Basgen,
M. S. Montesinos,
Astrid Weins,
Ashley C. Johnson,
E. Lander,
M. Garrett,
C. Hopkins,
A. Greka
|
7 |
2017 |
7 🐜
|
🐜
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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy
38 auth.
Moran Dvela-Levitt,
M. Kost-Alimova,
M. Emani,
Eva Kohnert,
Rebecca Thompson,
Eriene-Heidi Sidhom,
A. Rivadeneira,
N. Sahakian,
Julie Roignot,
Gregory Papagregoriou,
M. S. Montesinos,
A. Clark,
D. McKinney,
Juan Gutierrez,
M. Roth,
...
L. Ronco,
Esther Elonga,
T. Carter,
A. Gnirke,
Michelle Melanson,
K. Hartland,
Nicolas Wieder,
Jane C.-H. Hsu,
C. Deltas,
R. Hughey,
A. Bleyer,
S. Kmoch,
M. Živná,
V. Barešová,
S. Kota,
J. Schlondorff,
M. Heiman,
S. Alper,
Florence Wagner,
Astrid Weins,
T. Golub,
E. Lander,
A. Greka
|
7 |
2019 |
7 🐜
|
🦁
|
Signalling specificity in the Akt pathway in breast cancer.
A. Clark,
A. Toker
|
6 |
2014 |
6 🦁
|
🐜
|
Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.
11 auth.
S. Kugel,
Jessica L Feldman,
Mark A. Klein,
D. M. Silberman,
C. Sebastián,
C. Mermel,
...
S. Dobersch,
A. Clark,
G. Getz,
J. Denu,
R. Mostoslavsky
|
6 |
2015 |
6 🐜
|
🐜
|
A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury
36 auth.
M. Kost-Alimova,
Eriene-Heidi Sidhom,
A. Satyam,
Brian T Chamberlain,
Moran Dvela-Levitt,
Michelle Melanson,
S. Alper,
Jean Santos,
Juan Gutierrez,
Ayshwarya Subramanian,
P. Byrne,
Elizabeth Grinkevich,
Estefanía Reyes-Bricio,
Choah Kim,
A. Clark,
...
A. Watts,
Rebecca Thompson,
Jamie L. Marshall,
J. Pablo,
J. Coraor,
Julie Roignot,
K. Vernon,
Keith H. Keller,
A. Campbell,
M. Emani,
Matthew Racette,
Silvana Bazúa-Valenti,
Valeria Padovano,
Astrid Weins,
S. McAdoo,
F. Tam,
L. Ronco,
F. Wagner,
G. Tsokos,
Jillian L. Shaw,
A. Greka
|
5 |
2020 |
5 🐜
|
🐜
|
GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death.
16 auth.
Jonas Sieber,
Nicolas Wieder,
A. Clark,
Manuel Reitberger,
Sofia Matan,
Jeannine Schoenfelder,
Jianming Zhang,
A. Mandinova,
Joshua A. Bittker,
Juan Gutierrez,
...
O. Aygün,
N. Udeshi,
S. Carr,
P. Mundel,
A. Jehle,
A. Greka
|
4 |
2017 |
4 🐜
|
🐜
|
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
35 auth.
M. Alimova,
Eriene-Heidi Sidhom,
A. Satyam,
Moran Dvela-Levitt,
Michelle Melanson,
Brian T Chamberlain,
S. Alper,
Jean Santos,
Juan Gutierrez,
Ayshwarya Subramanian,
Elizabeth Grinkevich,
Estefania Reyes Bricio,
Choah Kim,
A. Clark,
A. Watts,
...
Rebecca Thompson,
Jamie L. Marshall,
J. Pablo,
J. Coraor,
Julie Roignot,
K. Vernon,
Keith H. Keller,
A. Campbell,
M. Emani,
Matthew Racette,
Silvana Bazúa-Valenti,
Valeria Padovano,
Astrid Weins,
S. McAdoo,
F. Tam,
L. Ronco,
F. Wagner,
G. Tsokos,
Jillian L. Shaw,
A. Greka
|
4 |
2020 |
4 🐜
|
🐜
|
Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities.
15 auth.
Marta Christov,
A. Clark,
Braden A. Corbin,
S. Hakroush,
E. Rhee,
H. Saito,
D. Brooks,
E. Hesse,
M. Bouxsein,
N. Galjart,
...
J. Jung,
P. Mundel,
H. Jüppner,
Astrid Weins,
A. Greka
|
4 |
2018 |
4 🐜
|
🐜
|
N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer’s disease mouse model
22 auth.
Stefano Suzzi,
T. Croese,
Adi Ravid,
Or Gold,
A. Clark,
S. Medina,
D. Kitsberg,
Miriam Adam,
K. Vernon,
Eva Kohnert,
...
Inbar Shapira,
S. Malitsky,
M. Itkin,
A. Brandis,
Tevie Mehlman,
T. Salame,
Sarah P. Colaiuta,
L. Cahalon,
M. Slyper,
A. Greka,
Naomi Habib,
Michal Schwartz
|
4 |
2023 |
4 🐜
|