|
π
|
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy
38 auth.
Moran Dvela-Levitt,
M. Kost-Alimova,
M. Emani,
Eva Kohnert,
Rebecca Thompson,
Eriene-Heidi Sidhom,
A. Rivadeneira,
N. Sahakian,
Julie Roignot,
Gregory Papagregoriou,
M. S. Montesinos,
A. Clark,
D. McKinney,
Juan Gutierrez,
M. Roth,
...
L. Ronco,
Esther Elonga,
T. Carter,
A. Gnirke,
Michelle Melanson,
K. Hartland,
Nicolas Wieder,
Jane C.-H. Hsu,
C. Deltas,
R. Hughey,
A. Bleyer,
S. Kmoch,
M. Ε½ivnΓ‘,
V. BareΕ‘ovΓ‘,
S. Kota,
J. Schlondorff,
M. Heiman,
S. Alper,
Florence Wagner,
Astrid Weins,
T. Golub,
E. Lander,
A. Greka
|
7 |
2019 |
7
π
|
|
π
|
Multiplexed G-ProteinβCoupled Receptor Caβ+ Flux Assays for High-Throughput Screening
7 auth.
Juan J. Miret,
Jiansu Zhang,
Hyunsuk Min,
Karina Lewis,
M. Roth,
Maura E. Charlton,
...
P. Bauer
|
4 |
2005 |
4
π
|
|
π
|
Abstract 917: AZD2014, a dual mTORC1 and mTORC2 inhibitor is differentiated from allosteric inhibitors of mTORC1 in ER+ breast cancer
16 auth.
S. Guichard,
Z. Howard,
D. Heathcote,
M. Roth,
G. Hughes,
J. Curwen,
J. Yates,
A. LogiΓ©,
S. Holt,
C. Chresta,
...
B. Davies,
Karine Malagu,
M. Hummersone,
Sarah L. Pass,
S. Green,
M. Pass
|
3 |
2012 |
3
π
|
|
π¦
|
FMRP Levels in Human Peripheral Blood Leukocytes Correlates with Intellectual Disability
M. Roth,
L. Ronco,
D. Cadavid,
B. Durbin-Johnson,
R. Hagerman,
F. Tassone
|
3 |
2021 |
3
π¦
|
|
π
|
Ftx-6058 Induces Fetal Hemoglobin Production and Ameliorates Disease Pathology in Sickle Cell Mice
9 auth.
D. Matson,
Keqiang Xie,
M. Roth,
B. Stuart,
P. Bruno,
I. Efremov,
...
Lorin Thompson,
S. Silver,
C. Moxham
|
2 |
2021 |
2
π
|
|
π
|
In Vivo Characterization of Ftx-6058, a Novel Small Molecular Fetal Hemoglobin Inducer for Sickle Cell Disease
9 auth.
Keqiang Xie,
M. Roth,
I. Efremov,
S. Silver,
L. Ronco,
L. Thompson,
...
K. Stickland,
C. Moxham,
O. Wallace
|
1 |
2020 |
1
π
|
|
π
|
P1498: INHIBITION OF POLYCOMB REPRESSIVE COMPLEX 2 THROUGH EED INDUCES FETAL HEMOGLOBIN IN HEALTHY AND SICKLE CELL DISEASE MODELS
9 auth.
B. Stuart,
P. Bruno,
D. Polioudakis,
M. Roth,
M. Wertz,
A. Edelstein,
...
I. Efremov,
D. Matson,
J. Dunn
|
1 |
2022 |
1
π
|
