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🐜
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Chemical genetics of Plasmodium falciparum
35 auth.
W. A. Guiguemde,
A. Shelat,
David C. Bouck,
Sandra Duffy,
Gregory J. Crowther,
P. Davis,
David C. Smithson,
M. Connelly,
Julie Clark,
Fangyi Zhu,
M. Jiménez-Díaz,
M. Martínez,
Emily B. Wilson,
A. Tripathi,
J. Gut,
...
E. Sharlow,
I. Bathurst,
Farah El Mazouni,
Joseph W. Fowble,
Isaac P. Forquer,
P. L. McGinley,
Steve Castro,
Iñigo Angulo-Barturen,
S. Ferrer,
P. Rosenthal,
J. Derisi,
D. Sullivan,
J. Lazo,
D. Roos,
M. Riscoe,
M. Phillips,
P. Rathod,
W. V. Van Voorhis,
V. Avery,
R. Guy
|
9 |
2010 |
9
🐜
|
|
🐬
|
Modeling of the spatial structure of eukaryotic ornithine decarboxylases
N. Grishin,
M. Phillips,
E. Goldsmith
|
8 |
1995 |
8
🐬
|
|
🦁
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A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
54 auth.
M. Phillips,
J. Lotharius,
K. Marsh,
John White,
A. Dayan,
K. White,
Jacqueline W. Njoroge,
Farah El Mazouni,
Y. Lao,
Sreekanth Kokkonda,
D. Tomchick,
Xiao-Yi Deng,
T. Laird,
S. Bhatia,
Sandra March,
...
Caroline L. Ng,
D. Fidock,
S. Wittlin,
S. Wittlin,
M. Lafuente-Monasterio,
Francisco Javier Gamo Benito,
Laura Maria Sanz Alonso,
M. Martínez,
M. Jiménez-Díaz,
S. Bazaga,
Iñigo Angulo-Barturen,
J. Haselden,
J. Louttit,
Yi Cui,
A. Sridhar,
A. Zeeman,
C. Kocken,
R. Sauerwein,
K. Dechering,
V. Avery,
Sandra Duffy,
M. Delves,
R. Sinden,
A. Ruecker,
Kristina S. Wickham,
R. Rochford,
Janet Gahagen,
L. Iyer,
E. Riccio,
J. Mirsalis,
Ian Bathhurst,
T. Rueckle,
Xavier C. Ding,
B. Campo,
D. Leroy,
M. Rogers,
P. Rathod,
J. Burrows,
S. Charman
|
8 |
2015 |
8
🦁
|
|
🦁
|
Targeted Nanodelivery of Drugs and Diagnostics.
M. Phillips,
Martin L. Gran,
N. Peppas
|
8 |
2010 |
8
🦁
|
|
🐢
|
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential.
25 auth.
J. Coterón,
Maria Marco,
J. Esquivias,
Xiao-Yi Deng,
K. White,
John White,
Maria Koltun,
Farah El Mazouni,
Sreekanth Kokkonda,
K. Katneni,
R. Bhamidipati,
David M. Shackleford,
Iñigo Angulo-Barturen,
S. Ferrer,
M. Jiménez-Díaz,
...
F. Gamo,
E. Goldsmith,
W. Charman,
I. Bathurst,
D. Floyd,
D. Matthews,
J. Burrows,
P. Rathod,
S. Charman,
M. Phillips
|
8 |
2011 |
8
🐢
|
|
🐢
|
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice.
13 auth.
R. Gujjar,
A. Marwaha,
Farah El Mazouni,
John White,
K. White,
S. Creason,
David M. Shackleford,
J. Baldwin,
W. Charman,
F. Buckner,
...
S. Charman,
P. Rathod,
M. Phillips
|
7 |
2009 |
7
🐢
|
|
🦁
|
Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.
M. Phillips,
P. Rathod
|
7 |
2010 |
7
🦁
|
|
🦁
|
Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.
7 auth.
M. Phillips,
R. Gujjar,
N. A. Malmquist,
John White,
Farah El Mazouni,
J. Baldwin,
...
P. Rathod
|
7 |
2008 |
7
🦁
|
|
🐢
|
High-throughput Screening for Potent and Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase*
7 auth.
J. Baldwin,
C. Michnoff,
N. A. Malmquist,
John White,
M. Roth,
P. Rathod,
...
M. Phillips
|
7 |
2005 |
7
🐢
|
|
🐜
|
An Alternative Polyamine Biosynthetic Pathway Is Widespread in Bacteria and Essential for Biofilm Formation in Vibrio cholerae*
7 auth.
Jeongmi Lee,
V. Sperandio,
D. Frantz,
J. Longgood,
A. Camilli,
M. Phillips,
...
A. Michael
|
7 |
2009 |
7
🐜
|
|
🐜
|
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
16 auth.
R. Gujjar,
Farah El Mazouni,
K. White,
John White,
S. Creason,
David M. Shackleford,
Xiao-Yi Deng,
W. Charman,
I. Bathurst,
J. Burrows,
...
D. Floyd,
D. Matthews,
F. Buckner,
S. Charman,
M. Phillips,
P. Rathod
|
7 |
2011 |
7
🐜
|
