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🐜
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Chemical genetics of Plasmodium falciparum
35 auth.
W. A. Guiguemde,
A. Shelat,
David C. Bouck,
Sandra Duffy,
Gregory J. Crowther,
P. Davis,
David C. Smithson,
M. Connelly,
Julie Clark,
Fangyi Zhu,
M. Jiménez-Díaz,
M. Martínez,
Emily B. Wilson,
A. Tripathi,
J. Gut,
...
E. Sharlow,
I. Bathurst,
Farah El Mazouni,
Joseph W. Fowble,
Isaac P. Forquer,
P. L. McGinley,
Steve Castro,
Iñigo Angulo-Barturen,
S. Ferrer,
P. Rosenthal,
J. Derisi,
D. Sullivan,
J. Lazo,
D. Roos,
M. Riscoe,
M. Phillips,
P. Rathod,
W. V. Van Voorhis,
V. Avery,
R. Guy
|
9 |
2010 |
9
🐜
|
|
🐜
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(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
50 auth.
M. Jiménez-Díaz,
D. Ebert,
Yandira G. Salinas,
Anupam Pradhan,
Adele M. Lehane,
Marie-Eve Myrand-Lapierre,
Kathleen G. O’Loughlin,
David M. Shackleford,
Mariana Justino de Almeida,
A. Carrillo,
Julie Clark,
Adelaide S M Dennis,
Jonathon Diep,
Xiaoyan Deng,
Sandra Duffy,
...
A. Endsley,
Greg Fedewa,
W. A. Guiguemde,
María G. Gómez,
Gloria Holbrook,
J. Horst,
Charles C. Kim,
Jian Liu,
Marcus C. S. Lee,
A. Matheny,
M. Martínez,
Gregory E. Miller,
A. Rodríguez-Alejandre,
Laura Sanz,
M. Sigal,
Natalie J. Spillman,
P. Stein,
Z. Wang,
Fangyi Zhu,
D. Waterson,
S. Knapp,
A. Shelat,
V. Avery,
D. Fidock,
F. Gamo,
S. Charman,
J. Mirsalis,
Hongshen Ma,
S. Ferrer,
K. Kirk,
Iñigo Angulo-Barturen,
D. Kyle,
J. Derisi,
D. Floyd,
R. Guy
|
7 |
2014 |
7
🐜
|
|
🐜
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Identification and Characterization of the First Small Molecule Inhibitor of MDMX*
15 auth.
D. Reed,
Ying Shen,
A. Shelat,
L. Arnold,
Antonio M Ferreira,
Fangyi Zhu,
Nicholas L. Mills,
David C. Smithson,
C. Regni,
D. Bashford,
...
S. Cicero,
Brenda A. Schulman,
A. Jochemsen,
R. K. Guy,
Michael A. Dyer
|
7 |
2010 |
7
🐜
|
|
🐜
|
Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a.
10 auth.
R. Brennan,
Sara M. Federico,
Cori L. Bradley,
Jiakun Zhang,
J. Flores-Otero,
M. Wilson,
...
C. Stewart,
Fangyi Zhu,
K. Guy,
M. Dyer
|
6 |
2011 |
6
🐜
|
|
🐜
|
Lead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials.
16 auth.
Yiqun Zhang,
Julie Clark,
M. Connelly,
Fangyi Zhu,
Jaeki Min,
W. A. Guiguemde,
Anupam Pradhan,
L. Iyer,
A. Furimsky,
J. Gow,
...
Toufan Parman,
Farah El Mazouni,
M. Phillips,
D. Kyle,
J. Mirsalis,
R. Guy
|
6 |
2012 |
6
🐜
|
|
🐜
|
Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration
16 auth.
Fan Zhang,
M. Tagen,
S. Throm,
J. Mallari,
Laura Miller,
R. Guy,
M. Dyer,
Richard T. Williams,
M. Roussel,
Katie M. Nemeth,
...
Fangyi Zhu,
Jiakun Zhang,
Min-Ping Lu,
J. Panetta,
N. Boulos,
C. Stewart
|
5 |
2011 |
5
🐜
|
|
🐜
|
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.
9 auth.
J. Mallari,
A. Shelat,
Aaron M Kosinski,
Conor R. Caffrey,
M. Connelly,
Fangyi Zhu,
...
James H. McKerrow,
R. Guy,
R. Guy
|
5 |
2008 |
5
🐜
|
|
🐜
|
Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.
9 auth.
J. Hwang,
L. Arnold,
Fangyi Zhu,
Aaron M Kosinski,
J. Thomas,
Mangano,
...
V. Setola,
B. Roth,
R. Guy
|
5 |
2009 |
5
🐜
|
|
🐜
|
Evaluation of Diarylureas for Activity Against Plasmodium falciparum.
19 auth.
Yiqun Zhang,
Marc O. Anderson,
J. L. Weisman,
Min-Ping Lu,
Cindy J. Choy,
Vincent A. Boyd,
Jeanine E. Price,
M. Sigal,
Julie Clark,
M. Connelly,
...
Fangyi Zhu,
W. A. Guiguemde,
C. Jeffries,
Lei Yang,
Andrew Lemoff,
Ally P Liou,
Thomas R. Webb,
J. DeRisi,
R. Guy
|
5 |
2010 |
5
🐜
|
|
🐜
|
Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity.
11 auth.
J. Hwang,
T. Kawasuji,
David J Lowes,
Julie Clark,
M. Connelly,
Fangyi Zhu,
...
W. A. Guiguemde,
M. Sigal,
Emily B. Wilson,
J. Derisi,
R. Guy
|
5 |
2011 |
5
🐜
|
