|
๐
|
Effective Use of PI3K and MEK Inhibitors to Treat Mutant K-Ras G12D and PIK3CA H1047R Murine Lung Cancers
21 auth.
J. Engelman,
Liang Chen,
X. Tan,
K. Crosby,
A. Guimaraes,
Rabi Upadhyay,
Michel Maira,
K. McNamara,
Samanthi A. Perera,
Youngchul Song,
...
L. Chirieac,
R. Kaur,
Angela Lightbown,
Jessica Simendinger,
Timothy Q Li,
R. Padera,
C. Garcรญa-echeverrรญa,
R. Weissleder,
U. Mahmood,
L. Cantley,
Kwok-kin Wong
|
10 |
2008 |
10
๐
|
|
๐
|
LKB1 modulates lung cancer differentiation and metastasis
34 auth.
H. Ji,
M. R. Ramsey,
D. Hayes,
C. Fan,
K. McNamara,
P. Kozlowski,
C. Torrice,
Michael C. Wu,
T. Shimamura,
Samanthi A. Perera,
M. Liang,
Dongpo Cai,
G. Naumov,
Lei Bao,
C. Contreras,
...
Danan Li,
Liang Chen,
J. Krishnamurthy,
J. Koivunen,
L. Chirieac,
R. Padera,
R. Bronson,
N. Lindeman,
D. Christiani,
Xihong Lin,
G. Shapiro,
P. Jรคnne,
B. Johnson,
M. Meyerson,
D. Kwiatkowski,
D. Castrillon,
N. Bardeesy,
N. Sharpless,
Kwok-kin Wong
|
10 |
2007 |
10
๐
|
|
๐
|
An orally available non-nucleotide STING agonist with antitumor activity
41 auth.
B. Pan,
Samanthi A. Perera,
J. Piesvaux,
J. Presland,
Gottfried K. Schroeder,
J. Cumming,
B. Trotter,
M. Altman,
A. Buevich,
B. Cash,
S. Cemerski,
Wonsuk Chang,
Yiping Chen,
P. Dandliker,
Guo Feng,
...
Andrew M Haidle,
T. Henderson,
James P. Jewell,
I. Kariv,
Ian Knemeyer,
J. Kopinja,
Brian M. Lacey,
J. Laskey,
C. Lesburg,
Rui Liang,
B. Long,
Min Lu,
Yanhong Ma,
E. Minnihan,
Greg O'Donnell,
Ryan Otte,
Laura Price,
L. Rakhilina,
B. Sauvagnat,
Sharad K Sharma,
S. Tyagarajan,
Hyun Woo,
D. Wyss,
Serena Xu,
D. J. Bennett,
G. Addona
|
8 |
2020 |
8
๐
|
|
๐ข
|
Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family.
M. E. Hahn,
S. Karchner,
Miriam A. Shapiro,
Samanthi A. Perera
|
8 |
1997 |
8
๐ข
|
|
๐
|
K-ras activation generates an inflammatory response in lung tumors
16 auth.
H. Ji,
A. Houghton,
T. Mariani,
Samanthi A. Perera,
Kim Cb,
R. Padera,
Giovanni Tonon,
K. McNamara,
Luiz A Marconcini,
A. Hezel,
...
N. El-Bardeesy,
R. Bronson,
D. Sugarbaker,
R. Maser,
S. Shapiro,
Kwok-kin Wong
|
8 |
2006 |
8
๐
|
|
๐
|
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
30 auth.
M. Sos,
Stefanie Fischer,
R. Ullrich,
M. Peifer,
J. Heuckmann,
Mirjam Koker,
Stefanie Heynck,
Isabel Stรผckrath,
J. Weiss,
Florian Fischer,
K. Michel,
A. Goel,
Lucรญa Regales,
K. Politi,
Samanthi A. Perera,
...
Matthรคus Getlik,
L. Heukamp,
S. Anseฬn,
T. Zander,
R. Beroukhim,
H. Kashkar,
K. Shokat,
W. Sellers,
D. Rauh,
C. Orr,
K. Hoeflich,
L. Friedman,
Kwok-kin Wong,
W. Pao,
Roman K. Thomas
|
7 |
2009 |
7
๐
|
|
๐
|
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.
23 auth.
Danan Li,
T. Shimamura,
H. Ji,
Liang Chen,
Henry J. Haringsma,
K. McNamara,
M. Liang,
Samanthi A. Perera,
Sara Zaghlul,
Christa L. Borgman,
...
S. Kubo,
Masaya Takahashi,
Yanping Sun,
L. Chirieac,
R. Padera,
N. Lindeman,
P. Jรคnne,
Roman K. Thomas,
M. Meyerson,
M. Eck,
J. Engelman,
G. Shapiro,
Kwok-kin Wong
|
7 |
2007 |
7
๐
|
|
๐ฆ
|
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy
22 auth.
Samanthi A. Perera,
Danan Li,
T. Shimamura,
M. G. Raso,
H. Ji,
Liang Chen,
Christa L. Borgman,
Sara Zaghlul,
K. Brandstetter,
S. Kubo,
...
Masaya Takahashi,
L. Chirieac,
R. Padera,
R. Bronson,
G. Shapiro,
H. Greulich,
M. Meyerson,
U. Guertler,
P. G. Chesa,
F. Solca,
I. Wistuba,
Kwok-kin Wong
|
7 |
2009 |
7
๐ฆ
|
|
๐
|
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
20 auth.
H. Ji,
Zhenxiong Wang,
Samanthi A. Perera,
Danan Li,
M. Liang,
Sara Zaghlul,
K. McNamara,
Liang Chen,
M. Albert,
Yanping Sun,
...
R. Al-Hashem,
L. Chirieac,
R. Padera,
R. Bronson,
Roman K. Thomas,
L. Garraway,
P. Jรคnne,
B. Johnson,
L. Chin,
Kwok-kin Wong
|
7 |
2007 |
7
๐
|
|
๐
|
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance.
22 auth.
T. Shimamura,
Danan Li,
H. Ji,
Henry J. Haringsma,
E. Liniker,
Christa L. Borgman,
April M. Lowell,
Y. Minami,
K. McNamara,
Samanthi A. Perera,
...
Sara Zaghlul,
Roman K. Thomas,
H. Greulich,
Susumu S. Kobayashi,
L. Chirieac,
R. Padera,
S. Kubo,
Masaya Takahashi,
D. Tenen,
M. Meyerson,
Kwok-kin Wong,
G. Shapiro
|
7 |
2008 |
7
๐
|
|
๐
|
Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of NonโSmall Cell Lung Cancer
19 auth.
T. Shimamura,
Samanthi A. Perera,
K. Foley,
Jim Sang,
S. Rodig,
Takayo Inoue,
Liang Chen,
Danan Li,
J. Carretero,
Yu-chen Li,
...
P. Sinha,
Christopher D. Carey,
Christa L. Borgman,
J. Jimenez,
M. Meyerson,
W. Ying,
J. Barsoum,
Kwok-kin Wong,
G. Shapiro
|
7 |
2012 |
7
๐
|
|
๐
|
Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion.
8 auth.
Jing Deng,
T. Shimamura,
Samanthi A. Perera,
N. Carlson,
Dongpo Cai,
G. Shapiro,
...
Kwok-kin Wong,
A. Letai
|
7 |
2007 |
7
๐
|
