|
🐜
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Effective Use of PI3K and MEK Inhibitors to Treat Mutant K-Ras G12D and PIK3CA H1047R Murine Lung Cancers
21 auth.
J. Engelman,
Liang Chen,
X. Tan,
K. Crosby,
A. Guimaraes,
Rabi Upadhyay,
Michel Maira,
K. McNamara,
Samanthi A. Perera,
Youngchul Song,
...
L. Chirieac,
R. Kaur,
Angela Lightbown,
Jessica Simendinger,
Timothy Q Li,
R. Padera,
C. García-echeverría,
R. Weissleder,
U. Mahmood,
L. Cantley,
Kwok-kin Wong
|
10 |
2008 |
10
🐜
|
|
🐜
|
LKB1 modulates lung cancer differentiation and metastasis
34 auth.
H. Ji,
M. R. Ramsey,
D. Hayes,
C. Fan,
K. McNamara,
P. Kozlowski,
C. Torrice,
Michael C. Wu,
T. Shimamura,
Samanthi A. Perera,
M. Liang,
Dongpo Cai,
G. Naumov,
Lei Bao,
C. Contreras,
...
Danan Li,
Liang Chen,
J. Krishnamurthy,
J. Koivunen,
L. Chirieac,
R. Padera,
R. Bronson,
N. Lindeman,
D. Christiani,
Xihong Lin,
G. Shapiro,
P. Jänne,
B. Johnson,
M. Meyerson,
D. Kwiatkowski,
D. Castrillon,
N. Bardeesy,
N. Sharpless,
Kwok-kin Wong
|
10 |
2007 |
10
🐜
|
|
🐜
|
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
15 auth.
Wenjun Zhou,
D. Ercan,
Liang Chen,
C. Yun,
Danan Li,
M. Capelletti,
A. Cortot,
L. Chirieac,
Roxana E. Iacob,
R. Padera,
...
J. Engen,
Kwok-kin Wong,
M. Eck,
N. Gray,
P. Jänne
|
9 |
2009 |
9
🐜
|
|
🐜
|
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
21 auth.
H. Ji,
Danan Li,
Liang Chen,
T. Shimamura,
Susumu S. Kobayashi,
K. McNamara,
U. Mahmood,
A. Mitchell,
Yangping Sun,
R. Al-Hashem,
...
L. Chirieac,
R. Padera,
R. Bronson,
William Kim,
P. Jänne,
G. Shapiro,
D. Tenen,
B. Johnson,
R. Weissleder,
N. Sharpless,
Kwok-kin Wong
|
8 |
2006 |
8
🐜
|
|
🐜
|
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.
23 auth.
Danan Li,
T. Shimamura,
H. Ji,
Liang Chen,
Henry J. Haringsma,
K. McNamara,
M. Liang,
Samanthi A. Perera,
Sara Zaghlul,
Christa L. Borgman,
...
S. Kubo,
Masaya Takahashi,
Yanping Sun,
L. Chirieac,
R. Padera,
N. Lindeman,
P. Jänne,
Roman K. Thomas,
M. Meyerson,
M. Eck,
J. Engelman,
G. Shapiro,
Kwok-kin Wong
|
7 |
2007 |
7
🐜
|
|
🐜
|
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy
22 auth.
Samanthi A. Perera,
Danan Li,
T. Shimamura,
M. G. Raso,
H. Ji,
Liang Chen,
Christa L. Borgman,
Sara Zaghlul,
K. Brandstetter,
S. Kubo,
...
Masaya Takahashi,
L. Chirieac,
R. Padera,
R. Bronson,
G. Shapiro,
H. Greulich,
M. Meyerson,
U. Guertler,
P. G. Chesa,
F. Solca,
I. Wistuba,
Kwok-kin Wong
|
7 |
2009 |
7
🐜
|
|
🐜
|
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
20 auth.
H. Ji,
Zhenxiong Wang,
Samanthi A. Perera,
Danan Li,
M. Liang,
Sara Zaghlul,
K. McNamara,
Liang Chen,
M. Albert,
Yanping Sun,
...
R. Al-Hashem,
L. Chirieac,
R. Padera,
R. Bronson,
Roman K. Thomas,
L. Garraway,
P. Jänne,
B. Johnson,
L. Chin,
Kwok-kin Wong
|
7 |
2007 |
7
🐜
|
|
🐜
|
Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non–Small Cell Lung Cancer
19 auth.
T. Shimamura,
Samanthi A. Perera,
K. Foley,
Jim Sang,
S. Rodig,
Takayo Inoue,
Liang Chen,
Danan Li,
J. Carretero,
Yu-chen Li,
...
P. Sinha,
Christopher D. Carey,
Christa L. Borgman,
J. Jimenez,
M. Meyerson,
W. Ying,
J. Barsoum,
Kwok-kin Wong,
G. Shapiro
|
7 |
2012 |
7
🐜
|
|
🐜
|
A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions
34 auth.
M. Damelin,
A. Bankovich,
J. Bernstein,
Justin Lucas,
Liang Chen,
Samuel A. Williams,
Albert Park,
Jorge L. Aguilar,
Elana Ernstoff,
M. Charati,
R. Dushin,
M. Aujay,
Christina Lee,
Hanna Ramoth,
Milly Milton,
...
J. Hampl,
S. Lazetic,
V. Pulito,
E. Rosfjord,
Yonglian Sun,
L. King,
F. Barletta,
A. Betts,
M. Guffroy,
Hadi Falahatpisheh,
C. J. O’Donnell,
R. Stull,
Marybeth Pysz,
P. Escarpe,
David R. Liu,
O. Foord,
H. Gerber,
P. Sapra,
S. Dylla
|
7 |
2017 |
7
🐜
|
|
🐜
|
Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer
22 auth.
O. Straume,
T. Shimamura,
Michael Lampa,
J. Carretero,
A. Øyan,
Di Jia,
Christa L. Borgman,
Margaret Soucheray,
S. Downing,
S. Short,
...
Soo-Young Kang,
Souming Wang,
Liang Chen,
K. Collett,
Ingeborg M. Bachmann,
Kwok-kin Wong,
G. Shapiro,
K. Kalland,
J. Folkman,
R. Watnick,
L. Akslen,
G. Naumov
|
7 |
2012 |
7
🐜
|
|
🐬
|
miRNA Biomarkers in Breast Cancer Detection and Management
S. Fu,
Liang Chen,
Y. Man
|
6 |
2011 |
6
🐬
|
|
🦁
|
Role of Deregulated microRNAs in Breast Cancer Progression Using FFPE Tissue
13 auth.
Liang Chen,
Youhuai Li,
Yebo Fu,
Jin Peng,
Meng-Hsuan Mo,
M. Stamatakos,
C. Teal,
R. Brem,
A. Stojadinovic,
M. Grinkemeyer,
...
T. McCaffrey,
Y. Man,
S. Fu
|
6 |
2013 |
6
🦁
|
