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Yiping Chen

Bioorganic & Medicinal Chemistry Letters, Science, Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of biomolecular screening, Molecular Cancer Therapeutics, Immunology, Molecular and Cellular Endocrinology Show more
9
Role
Title
Level Year L/R
🐜 An orally available non-nucleotide STING agonist with antitumor activity
41 auth. B. Pan, Samanthi A. Perera, J. Piesvaux, J. Presland, Gottfried K. Schroeder, J. Cumming, B. Trotter, M. Altman, A. Buevich, B. Cash, S. Cemerski, Wonsuk Chang, Yiping Chen, P. Dandliker, Guo Feng, ... Andrew M Haidle, T. Henderson, James P. Jewell, I. Kariv, Ian Knemeyer, J. Kopinja, Brian M. Lacey, J. Laskey, C. Lesburg, Rui Liang, B. Long, Min Lu, Yanhong Ma, E. Minnihan, Greg O'Donnell, Ryan Otte, Laura Price, L. Rakhilina, B. Sauvagnat, Sharad K Sharma, S. Tyagarajan, Hyun Woo, D. Wyss, Serena Xu, D. J. Bennett, G. Addona 		8 2020
8
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🐜 Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.
36 auth. Wonsuk Chang, M. Altman, C. Lesburg, Samanthi A. Perera, J. Piesvaux, Gottfried K. Schroeder, D. Wyss, S. Cemerski, Yiping Chen, Edward Dinunzio, Andrew M Haidle, Thu Ho, I. Kariv, Ian Knemeyer, J. Kopinja, ... Brian M. Lacey, J. Laskey, Jongwon Lim, B. Long, Yanhong Ma, Matthew L. Maddess, B. Pan, J. Presland, E. Spooner, D. Steinhuebel, Quang Truong, Zhibo Zhang, Jianmin Fu, G. Addona, Alan B. Northrup, E. Parmee, J. Tata, D. J. Bennett, J. Cumming, T. Siu, B. Trotter 		6 2022
6
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🐜 Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.
19 auth. Jongwon Lim, M. Altman, James Baker, Jason D. Brubaker, Hongmin Chen, Yiping Chen, T. Fischmann, Craig R Gibeau, M. Kleinschek, Erica Leccese, ... C. Lesburg, J. Maclean, L. Moy, E. Mulrooney, J. Presland, L. Rakhilina, Graham M. Smith, D. Steinhuebel, Ruojing Yang 		5 2015
5
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🐜 Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.
15 auth. Jongwon Lim, M. Altman, James Baker, Jason D. Brubaker, Hongmin Chen, Yiping Chen, M. Kleinschek, Chaomin Li, Duan Liu, J. Maclean, ... E. Mulrooney, J. Presland, L. Rakhilina, Graham F. Smith, Ruojing Yang 		4 2015
4
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🐜 Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.
33 auth. Graham F. Smith, M. Altman, Brian M. Andresen, James Baker, Jason D. Brubaker, Hongmin Chen, Yiping Chen, M. Childers, Anthony E Donofrio, Heidi Ferguson, C. Fischer, T. Fischmann, Craig R Gibeau, A. Hicks, Sue Jin, ... Sam D Kattar, M. Kleinschek, Erica Leccese, C. Lesburg, Chaomin Li, Jongwon Lim, Duan Liu, J. Maclean, Farukh Mansoor, L. Moy, E. Mulrooney, Antoaneta S. Necheva, J. Presland, L. Rakhilina, Ruojing Yang, Luis E. Torres, J. Zhang-Hoover, Alan B. Northrup 		4 2017
4
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🐜 Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-ΞΊB Pathway
29 auth. V. Kutilek, C. Andrews, M. Richards, Zangwei Xu, Tianxiao Sun, Yiping Chen, Andrew Hashke, N. Smotrov, Rafael B. Fernandez, E. Nickbarg, Chad Chamberlin, B. Sauvagnat, Patrick J. Curran, Ryan P. Boinay, P. Saradjian, ... S. Allen, N. Byrne, N. Elsen, Rachael E Ford, D. Hall, M. Kornienko, K. Rickert, Sujata Sharma, J. Shipman, K. Lumb, K. Coleman, P. Dandliker, I. Kariv, B. Beutel 		4 2016
4
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🐜 STimulator of INterferon Genes Agonism Accelerates Antitumor Activity in Poorly Immunogenic Tumors
29 auth. Samanthi A. Perera, J. Kopinja, Yanhong Ma, E. Muise, J. Laskey, K. Chakravarthy, Yiping Chen, L. Cui, J. Presland, M. Sathe, Sarah Javaid, E. Minnihan, Heidi Ferguson, J. Piesvaux, B. Pan, ... Shuxia Zhao, S. K. Sharma, Hyun Woo, Vincenzo Pucci, Ian Knemeyer, S. Cemerski, J. Cumming, B. Trotter, A. Tse, A. Khilnani, S. Ranganath, B. Long, D. J. Bennett, G. Addona 		2 2021
2
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🐜 Abstract 4721: Combining STING agonists with an anti-PD-1 antagonist results in marked antitumor activity in immune-excluded tumors
21 auth. Samanthi A. Perera, J. Kopinja, Yanhong Ma, J. Laskey, K. Chakravarthy, Yiping Chen, L. Cui, J. Presland, Shuxia Zhao, E. Minnihan, ... Heidi Ferguson, J. Piesvaux, B. Pan, Hyun Woo, Ian Knemeyer, S. Cemerski, J. Cumming, Wesley B. Trotter, A. Tse, G. Addona, B. Long 		2 2018
2
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🐜 Determination of EPAC2 function using EPAC2 null Min6 sublines generated through CRISPR-Cas9 technology
8 auth. Haiyan Xu, Yi Yang, Yiping Chen, U. Mueller, Sharanya Iyer, J. Presland, ... Ruojing Yang, I. Kariv 		0 2018
0
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