|
🐜
|
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
19 auth.
R. Manguso,
Hans W. Pope,
Margaret D. Zimmer,
Flavian D. Brown,
Kathleen B. Yates,
Brian C. Miller,
Natalie B Collins,
K. Bi,
M. LaFleur,
Vikram R. Juneja,
...
Sarah A. Weiss,
J. Lo,
D. Fisher,
Diana Miao,
E. V. Allen,
D. Root,
Arlene H. Sharpe,
John G Doench,
W. Haining
|
9 |
2017 |
9
🐜
|
|
🦁
|
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity
8 auth.
Vikram R. Juneja,
Kathleen McGuire,
R. Manguso,
M. LaFleur,
Natalie B Collins,
W. Haining,
...
G. Freeman,
Arlene H. Sharpe
|
9 |
2017 |
9
🦁
|
|
🐜
|
Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth
22 auth.
S. Kleffel,
C. Posch,
S. Barthel,
Hansgeorg Mueller,
C. Schlapbach,
E. Guenova,
C. Elco,
N. Lee,
Vikram R. Juneja,
Q. Zhan,
...
C. Lian,
R. Thomi,
W. Hoetzenecker,
A. Cozzio,
R. Dummer,
M. Mihm,
K. Flaherty,
M. Frank,
G. Murphy,
A. Sharpe,
T. Kupper,
T. Schatton
|
9 |
2015 |
9
🐜
|
|
🐜
|
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
22 auth.
A. Ringel,
Jefte M. Drijvers,
G. Baker,
Alessia Catozzi,
J. García-Cañaveras,
Brandon M. Gassaway,
Brian C. Miller,
Vikram R. Juneja,
Thao H Nguyen,
Shakchhi Joshi,
...
Cong-Hui Yao,
H. Yoon,
P. Sage,
M. LaFleur,
Justin D. Trombley,
C. Jacobson,
Z. Maliga,
S. Gygi,
P. Sorger,
J. Rabinowitz,
A. Sharpe,
M. Haigis
|
8 |
2020 |
8
🐜
|
|
🐜
|
Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade
15 auth.
Z. Cooper,
Vikram R. Juneja,
P. Sage,
Dennie T. Frederick,
A. Piris,
D. Mitra,
J. Lo,
F. Hodi,
G. Freeman,
M. Bosenberg,
...
M. McMahon,
K. Flaherty,
D. Fisher,
A. Sharpe,
J. Wargo
|
7 |
2014 |
7
🐜
|
|
🐜
|
Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity
12 auth.
A. Paterson,
S. Lovitch,
P. Sage,
Vikram R. Juneja,
Youjin Lee,
Justin D. Trombley,
...
C. Arancibia-Cárcamo,
R. Sobel,
A. Rudensky,
V. Kuchroo,
G. Freeman,
A. Sharpe
|
7 |
2015 |
7
🐜
|
|
🐜
|
Suppression by TFR cells leads to durable and selective inhibition of B cell effector function
17 auth.
P. Sage,
P. Sage,
N. Ron-Harel,
Vikram R. Juneja,
Vikram R. Juneja,
Debattama R. Sen,
Seth Maleri,
Seth Maleri,
W. Sungnak,
W. Sungnak,
...
V. Kuchroo,
V. Kuchroo,
W. Haining,
Nicolas Chevrier,
M. Haigis,
A. Sharpe,
A. Sharpe
|
7 |
2016 |
7
🐜
|
|
🐜
|
Suppression by TFR cells leads to durable and selective inhibition of B cell effector function
17 auth.
P. Sage,
P. Sage,
N. Ron-Harel,
Vikram R. Juneja,
Vikram R. Juneja,
Debattama R. Sen,
Seth Maleri,
Seth Maleri,
W. Sungnak,
W. Sungnak,
...
V. Kuchroo,
V. Kuchroo,
W. Haining,
Nicolas Chevrier,
M. Haigis,
A. Sharpe,
A. Sharpe
|
7 |
2016 |
7
🐜
|
|
🐜
|
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
18 auth.
Catherine Tan,
J. Kuchroo,
P. Sage,
D. Liang,
Loise M. Francisco,
Jessica Buck,
Y. R. Thaker,
Qianxia Zhang,
Shannon L. McArdel,
Vikram R. Juneja,
...
Sun Jung Lee,
S. Lovitch,
C. Lian,
G. Murphy,
B. Blazar,
D. Vignali,
G. Freeman,
A. Sharpe
|
7 |
2020 |
7
🐜
|
|
🐜
|
Tracking mesenchymal stem cells with iron oxide nanoparticle loaded poly(lactide-co-glycolide) microparticles.
14 auth.
Chenjie Xu,
David Miranda-Nieves,
J. Ankrum,
Mads Emil Matthiesen,
Joseph A. Phillips,
Isaac Roes,
G. Wojtkiewicz,
Vikram R. Juneja,
Jens Roat Kultima,
Weian Zhao,
...
P. Vemula,
Charles P. Lin,
M. Nahrendorf,
J. Karp
|
7 |
2012 |
7
🐜
|
|
🐜
|
BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes
10 auth.
Z. Cooper,
Dennie T. Frederick,
Vikram R. Juneja,
R. Sullivan,
D. Lawrence,
A. Piris,
...
A. Sharpe,
D. Fisher,
K. Flaherty,
J. Wargo
|
6 |
2013 |
6
🐜
|
