|
π
|
Improved survival with vemurafenib in melanoma with BRAF V600E mutation.
28 auth.
P. Chapman,
A. Hauschild,
C. Robert,
J. Haanen,
P. Ascierto,
J. Larkin,
R. Dummer,
C. Garbe,
A. Testori,
M. Maio,
D. Hogg,
P. Lorigan,
C. LebbΓ©,
T. Jouary,
D. Schadendorf,
...
A. Ribas,
S. O'Day,
J. Sosman,
J. Kirkwood,
A. Eggermont,
B. DrΓ©no,
K. Nolop,
Jiang Li,
B. Nelson,
J. Hou,
Richard J Lee,
K. Flaherty,
G. McArthur
|
12 |
2011 |
12
π
|
|
π
|
Final version of 2009 AJCC melanoma staging and classification.
20 auth.
C. Balch,
J. Gershenwald,
S. Soong,
J. Thompson,
M. Atkins,
D. Byrd,
A. Buzaid,
A. Cochran,
D. Coit,
Shouluan Ding,
...
A. Eggermont,
K. Flaherty,
P. Gimotty,
J. Kirkwood,
K. McMasters,
M. Mihm,
D. Morton,
M. Ross,
A. Sober,
V. Sondak
|
12 |
2009 |
12
π
|
|
π
|
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
37 auth.
I. Tirosh,
B. Izar,
S. Prakadan,
M. Wadsworth,
D. Treacy,
John J. Trombetta,
Asaf Rotem,
Christopher Rodman,
C. Lian,
G. Murphy,
M. Fallahi-Sichani,
K. Dutton-Regester,
Jia-Ren Lin,
Ofir Cohen,
Parin Shah,
...
Diana Lu,
Alex S Genshaft,
T. Hughes,
Carly G. K. Ziegler,
S. Kazer,
A. Gaillard,
Kellie E. Kolb,
A. Villani,
Cory M. Johannessen,
A. Andreev,
E. V. Van Allen,
M. Bertagnolli,
P. Sorger,
R. Sullivan,
K. Flaherty,
Dennie T. Frederick,
Judit JanΓ©-Valbuena,
Charles H. Yoon,
O. Rozenblatt-Rosen,
A. Shalek,
A. Regev,
L. Garraway
|
11 |
2016 |
11
π
|
|
π¦
|
Inhibition of mutated, activated BRAF in metastatic melanoma.
11 auth.
K. Flaherty,
I. Puzanov,
Kevin B. Kim,
A. Ribas,
G. McArthur,
J. Sosman,
...
P. O'dwyer,
Richard J Lee,
J. Grippo,
K. Nolop,
P. Chapman
|
11 |
2010 |
11
π¦
|
|
π¦
|
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations.
26 auth.
K. Flaherty,
J. Infante,
A. Daud,
R. Gonzalez,
R. Kefford,
J. Sosman,
O. Hamid,
L. Schuchter,
J. Cebon,
N. Ibrahim,
R. Kudchadkar,
H. Burris,
G. Falchook,
A. Algazi,
K. Lewis,
...
G. Long,
I. Puzanov,
P. Lebowitz,
A. Singh,
S. Little,
P. Sun,
A. Allred,
D. Ouellet,
Kevin B. Kim,
K. Patel,
J. Weber
|
11 |
2012 |
11
π¦
|
|
π
|
Genomic Classification of Cutaneous Melanoma
352 auth.
Rehan Akbani,
K. Akdemir,
B. A. Aksoy,
Monique Albert,
Adrian Ally,
S. Amin,
H. Arachchi,
Arshi Arora,
J. Auman,
Brenda Ayala,
J. Baboud,
M. Balasundaram,
S. Balu,
N. Barnabas,
J. Bartlett,
...
Pamela Bartlett,
B. Bastian,
S. Baylin,
M. Behera,
D. Belyaev,
C. Benz,
Brady Bernard,
R. Beroukhim,
Natalie Bir,
Aaron D. Black,
T. Bodenheimer,
L. Boice,
G. Boland,
R. Bono,
Moiz Bootwalla,
M. Bosenberg,
Jay Bowen,
R. Bowlby,
C. Bristow,
Laura Brockway-Lunardi,
Denise Brooks,
Jakub BrzeziΕski,
W. Bshara,
Elizabeth Buda,
W. Burns,
Y. Butterfield,
Michael Button,
T. Calderone,
G. Cappellini,
Candace D. Carter,
S. Carter,
L. Cherney,
A. Cherniack,
A. Chevalier,
L. Chin,
Juok Cho,
R. Cho,
Yoon-La Choi,
Andy Chu,
Sudha Chudamani,
K. Cibulskis,
G. Ciriello,
A. Clarke,
S. Coons,
L. Cope,
D. Crain,
Erin E. Curley,
Ludmila V. Danilova,
S. DβAtri,
Tanja Davidsen,
M. Davies,
K. Delman,
John A. Demchok,
Qixia A. Deng,
Y. L. Deribe,
Noreen Dhalla,
R. Dhir,
D. Dicara,
Michael Dinikin,
M. Dubina,
J. S. Ebrom,
Sophie C. Egea,
G. Eley,
J. Engel,
J. Eschbacher,
K. Fedosenko,
Ina Felau,
T. Fennell,
M. Ferguson,
Sheila A Fisher,
K. Flaherty,
S. Frazer,
J. Frick,
Victoria Fulidou,
S. Gabriel,
Jianjiong Gao,
J. Gardner,
L. Garraway,
J. Gastier-Foster,
Carmelo Gaudioso,
Nils Gehlenborg,
G. Genovese,
M. Gerken,
J. Gershenwald,
G. Getz,
C. Gomez-Fernandez,
T. Gribbin,
J. Grimsby,
Benjamin E. Gross,
R. Guin,
Tony Gutschner,
Angela Hadjipanayis,
R. Halaban,
B. Hanf,
D. Haussler,
L. Haydu,
D. Hayes,
N. Hayward,
David I Heiman,
Lynn M. Herbert,
J. Herman,
P. Hersey,
K. Hoadley,
Eran Hodis,
R. Holt,
D. Hoon,
Susan Hoppough,
A. Hoyle,
F. Huang,
Meijuan Huang,
S. Huang,
C. Hutter,
Matthew Ibbs,
L. Iype,
A. Jacobsen,
V. Jakrot,
Alyssa Janning,
W. Jeck,
S. Jefferys,
M. Jensen,
Corbin D. Jones,
Steven J. M. Jones,
Z. Ju,
H. Kakavand,
Hyojin Kang,
R. Kefford,
F. Khuri,
Jaegil Kim,
J. Kirkwood,
J. Klode,
Anil Korkut,
Konstanty Korski,
M. Krauthammer,
R. Kucherlapati,
L. Kwong,
W. Kycler,
M. Ladanyi,
Phillip H. Lai,
P. Laird,
E. Lander,
M. Lawrence,
A. Lazar,
Radoslaw ΕaΕΊniak,
Darlene Lee,
Jeffrey E. Lee,
Junehawk Lee,
Kenneth Lee,
Semin Lee,
William Lee,
E. Leporowska,
K. Leraas,
H. Li,
T. Lichtenberg,
Lee T Lichtenstein,
Pei Lin,
Shiyun Ling,
Jia Liu,
Ouida Liu,
Wenbin Liu,
G. Long,
Yiling Lu,
Singer Ma,
Yussanne Ma,
A. Mackiewicz,
Harshad S. Mahadeshwar,
Jared C Malke,
D. Mallery,
G. Manikhas,
G. Mann,
M. Marra,
Brenna Matejka,
Michael Mayo,
Sousan Mehrabi,
S. Meng,
M. Meyerson,
P. Mieczkowski,
John P Miller,
Martin L. Miller,
G. Mills,
F. Moiseenko,
Richard A. Moore,
S. Morris,
C. Morrison,
D. Morton,
S. Moschos,
Lisle E. Mose,
F. Muller,
A. Mungall,
D. Murawa,
P. Murawa,
Bradley A. Murray,
L. Nezi,
S. Ng,
D. Nicholson,
M. Noble,
A. Osunkoya,
T. Owonikoko,
B. Ozenberger,
E. Pagani,
O. Paklina,
A. Pantazi,
Michael G Parfenov,
J. Parfitt,
P. Park,
W. Park,
J. Parker,
F. Passarelli,
R. Penny,
C. Perou,
T. Pihl,
O. Potapova,
V. Prieto,
A. Protopopov,
M. Quinn,
Amie Radenbaugh,
Kunal Rai,
S. Ramalingam,
Ayush T. Raman,
N. Ramirez,
Ricardo Ramirez,
U. Rao,
W. Rathmell,
X. Ren,
Sheila M. Reynolds,
J. Roach,
A. G. Robertson,
M. Ross,
J. Roszik,
G. Russo,
G. Saksena,
Charles Saller,
Yardena Samuels,
C. Sander,
C. Sander,
G. Sandusky,
Netty G Santoso,
M. Saul,
R. Saw,
D. Schadendorf,
J. Schein,
N. Schultz,
S. Schumacher,
Charles Schwallier,
R. Scolyer,
J. Seidman,
P. C. Sekhar,
H. Sekhon,
Y. ΕenbabaoΔlu,
S. Seth,
K. Shannon,
S. Sharpe,
N. Sharpless,
K. Shaw,
C. Shelton,
T. Shelton,
R. Shen,
Margi Sheth,
Yan Shi,
C. Shiau,
I. Shmulevich,
G. Sica,
J. Simons,
Rileen Sinha,
Payal Sipahimalani,
H. Sofia,
Matthew G. Soloway,
Xingzhi Song,
C. Sougnez,
A. Spillane,
A. SpychaΕa,
J. Stretch,
Joshua M. Stuart,
W. Suchorska,
A. Sucker,
S. O. Sumer,
Yichao Sun,
M. Synott,
B. Tabak,
Teresa R. Tabler,
Angela Tam,
Donghui Tan,
Jiabin Tang,
R. Tarnuzzer,
Katherine Tarvin,
Honorata Tatka,
B. Taylor,
M. Teresiak,
N. Thiessen,
J. Thompson,
L. Thorne,
V. Thorsson,
J. Trent,
T. Triche,
K. Tsai,
Pei-Ling Tsou,
D. V. Berg,
E. Allen,
Umadevi Veluvolu,
R. Verhaak,
Douglas Voet,
Olga Voronina,
Vonn Walter,
Jessica L Walton,
Yunhu Wan,
Yuling Wang,
Zhining Wang,
S. Waring,
I. Watson,
Nils Weinhold,
J. Weinstein,
D. Weisenberger,
P. White,
M. Wilkerson,
J. Wilmott,
L. Wise,
M. Wiznerowicz,
S. Woodman,
Chang-Jiun Wu,
Chia-Chin Wu,
Junyuan Wu,
Ye Wu,
Ruibin Xi,
A. W. Xu,
D. Yang,
Liming Yang,
Lixing Yang,
Travis Zack,
J. Zenklusen,
Hailei Zhang,
Jianhua Zhang,
Wei Zhang,
Xiaobei Zhao,
Jingchun Zhu,
Kelsey Zhu,
L. Zimmer,
E. Zmuda,
L. Zou
|
11 |
2015 |
11
π
|
|
π
|
Improved overall survival in melanoma with combined dabrafenib and trametinib.
27 auth.
C. Robert,
B. Karaszewska,
J. Schachter,
P. Rutkowski,
A. Mackiewicz,
D. Stroiakovski,
M. Lichinitser,
R. Dummer,
F. Grange,
L. Mortier,
V. Chiarion-Sileni,
K. Drucis,
I. Krajsova,
A. Hauschild,
P. Lorigan,
...
P. Wolter,
G. Long,
K. Flaherty,
P. Nathan,
A. Ribas,
Anne-Marie Martin,
P. Sun,
W. Crist,
J. Legos,
S. Rubin,
S. Little,
D. Schadendorf
|
11 |
2015 |
11
π
|
|
π
|
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib.
25 auth.
J. Sosman,
Kevin B. Kim,
L. Schuchter,
R. Gonzalez,
A. Pavlick,
J. Weber,
G. McArthur,
Thomas E. Hutson,
S. Moschos,
K. Flaherty,
P. Hersey,
R. Kefford,
D. Lawrence,
I. Puzanov,
K. Lewis,
...
R. Amaravadi,
B. Chmielowski,
H. Lawrence,
Y. Shyr,
Fei Ye,
Jiang Li,
K. Nolop,
Richard J Lee,
A. Joe,
A. Ribas
|
11 |
2012 |
11
π
|
|
π¦
|
Improved survival with MEK inhibition in BRAF-mutated melanoma.
25 auth.
K. Flaherty,
C. Robert,
P. Hersey,
P. Nathan,
C. Garbe,
M. Milhem,
L. Demidov,
J. Hassel,
P. Rutkowski,
P. Mohr,
R. Dummer,
U. Trefzer,
J. Larkin,
J. Utikal,
B. DrΓ©no,
...
M. Nyakas,
M. Middleton,
J. Becker,
M. Casey,
L. Sherman,
Frank Wu,
D. Ouellet,
Anne-Marie Martin,
K. Patel,
D. Schadendorf
|
10 |
2012 |
10
π¦
|
|
π
|
Melanoma staging: Evidenceβbased changes in the American Joint Committee on Cancer eighth edition cancer staging manual
15 auth.
J. Gershenwald,
R. Scolyer,
K. Hess,
V. Sondak,
G. Long,
M. Ross,
A. Lazar,
M. Faries,
J. Kirkwood,
G. McArthur,
...
L. Haydu,
A. Eggermont,
K. Flaherty,
C. Balch,
J. Thompson
|
10 |
2017 |
10
π
|
|
π
|
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
40 auth.
G. Bollag,
P. Hirth,
J. Tsai,
Jiazhong Zhang,
P. Ibrahim,
Hanna Cho,
W. Spevak,
Chao Zhang,
Ying Zhang,
G. Habets,
Elizabeth A. Burton,
B. Wong,
Garson Tsang,
B. West,
Ben J. Powell,
...
Rafe Shellooe,
A. Marimuthu,
Hoa T. Nguyen,
Kam Y. J. Zhang,
D. Artis,
J. Schlessinger,
F. Su,
B. Higgins,
R. Iyer,
K. DβAndrea,
A. Koehler,
M. Stumm,
P. Lin,
Richard J Lee,
J. Grippo,
I. Puzanov,
Kevin B. Kim,
A. Ribas,
G. McArthur,
J. Sosman,
P. Chapman,
K. Flaherty,
Xiaowei Xu,
K. Nathanson,
K. Nolop
|
10 |
2010 |
10
π
|
|
π’
|
Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma.
35 auth.
G. Long,
D. Stroyakovskiy,
H. Gogas,
E. Levchenko,
F. de Braud,
J. Larkin,
C. Garbe,
T. Jouary,
A. Hauschild,
J. Grob,
V. Chiarion Sileni,
C. LebbΓ©,
M. MandalΓ ,
M. Millward,
A. Arance,
...
I. Bondarenko,
J. Haanen,
J. Hansson,
J. Utikal,
V. Ferraresi,
N. Kovalenko,
P. Mohr,
V. Probachai,
D. Schadendorf,
P. Nathan,
C. Robert,
A. Ribas,
D. Demarini,
J. Irani,
M. Casey,
D. Ouellet,
Anne-Marie Martin,
N. Le,
K. Patel,
K. Flaherty
|
10 |
2014 |
10
π’
|
|
π
|
Tumor microenvironment induces innate RAF-inhibitor resistance through HGF secretion
19 auth.
R. Straussman,
Teppei Morikawa,
K. Shee,
Michal Barzily-Rokni,
Z. Qian,
Jinyan Du,
Ashli Davis,
Margaret M. Mongare,
Joshua Gould,
Dennie T. Frederick,
...
Z. Cooper,
P. Chapman,
D. Solit,
A. Ribas,
R. Lo,
K. Flaherty,
S. Ogino,
J. Wargo,
T. Golub
|
10 |
2012 |
10
π
|
|
π
|
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
35 auth.
Moshe Sade-Feldman,
Keren Yizhak,
Stacey L. Bjorgaard,
John P. Ray,
Carl G. de Boer,
R. Jenkins,
David J. Lieb,
Jonathan H. Chen,
Dennie T. Frederick,
Michal Barzily-Rokni,
S. Freeman,
A. Reuben,
P. Hoover,
A. Villani,
E. Ivanova,
...
A. Portell,
Patrick H. Lizotte,
A. Aref,
J. Eliane,
Marc R. Hammond,
Hans Vitzthum,
S. Blackmon,
Bo Li,
V. Gopalakrishnan,
S. Reddy,
Z. Cooper,
C. Paweletz,
D. Barbie,
A. Stemmer-Rachamimov,
K. Flaherty,
J. Wargo,
G. Boland,
R. Sullivan,
G. Getz,
N. Hacohen
|
10 |
2018 |
10
π
|
|
π
|
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
24 auth.
Poulikos I. Poulikakos,
Yogindra Persaud,
M. Janakiraman,
X. Kong,
Charles Ng,
G. Moriceau,
Hubing Shi,
M. Atefi,
B. Titz,
M. Gabay,
...
M. Salton,
K. Dahlman,
M. Tadi,
J. Wargo,
K. Flaherty,
M. Kelley,
T. Misteli,
P. Chapman,
J. Sosman,
T. Graeber,
A. Ribas,
R. Lo,
N. Rosen,
D. Solit
|
10 |
2011 |
10
π
|
