|
π
|
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
40 auth.
G. Bollag,
P. Hirth,
J. Tsai,
Jiazhong Zhang,
P. Ibrahim,
Hanna Cho,
W. Spevak,
Chao Zhang,
Ying Zhang,
G. Habets,
Elizabeth A. Burton,
B. Wong,
Garson Tsang,
B. West,
Ben J. Powell,
...
Rafe Shellooe,
A. Marimuthu,
Hoa T. Nguyen,
Kam Y. J. Zhang,
D. Artis,
J. Schlessinger,
F. Su,
B. Higgins,
R. Iyer,
K. DβAndrea,
A. Koehler,
M. Stumm,
P. Lin,
Richard J Lee,
J. Grippo,
I. Puzanov,
Kevin B. Kim,
A. Ribas,
G. McArthur,
J. Sosman,
P. Chapman,
K. Flaherty,
Xiaowei Xu,
K. Nathanson,
K. Nolop
|
10 |
2010 |
10
π
|
|
π
|
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
38 auth.
J. Tsai,
John T. Lee,
Weiru Wang,
Jiazhong Zhang,
Hanna Cho,
Shumeye Mamo,
R. Bremer,
S. Gillette,
Jun Kong,
N. Haass,
Katrin Sproesser,
Ling Li,
K. Smalley,
D. Fong,
Yong Zhu,
...
A. Marimuthu,
Hoa T. Nguyen,
Billy Lam,
Jennifer Liu,
Ivana Cheung,
J. Rice,
Yoshihisa Suzuki,
C. Luu,
Calvin Settachatgul,
Rafe Shellooe,
J. Cantwell,
Sung-Hou Kim,
J. Schlessinger,
Kam Y. J. Zhang,
B. West,
Ben J. Powell,
G. Habets,
Chao Zhang,
P. Ibrahim,
P. Hirth,
D. Artis,
M. Herlyn,
G. Bollag
|
10 |
2008 |
10
π
|
|
π
|
RAF inhibitors that evade paradoxical MAPK pathway activation
35 auth.
Chao Zhang,
W. Spevak,
Ying Zhang,
Elizabeth A. Burton,
Yanwen Ma,
G. Habets,
Jiazhong Zhang,
Jacki Lin,
T. Ewing,
Bernice Matusow,
Garson Tsang,
A. Marimuthu,
Hanna Cho,
Guoxiang Wu,
Weiru Wang,
...
D. Fong,
Hoa T. Nguyen,
S. Shi,
P. Womack,
Marika Nespi,
Rafe Shellooe,
Heidi Carias,
Ben J. Powell,
E. Light,
L. Sanftner,
J. Walters,
J. Tsai,
B. West,
G. Visor,
Hamid Rezaei,
P. Lin,
K. Nolop,
P. Ibrahim,
P. Hirth,
G. Bollag
|
8 |
2015 |
8
π
|
|
π
|
Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
34 auth.
K. Donovan,
F. Ferguson,
Jonathan W. Bushman,
N. Eleuteri,
Debabrata Bhunia,
Seongshick Ryu,
L. Tan,
K. Shi,
Hong Yue,
Xiaoxi Liu,
D. Dobrovolsky,
Baishan Jiang,
Jinhua Wang,
Mingfeng Hao,
Inchul You,
...
Mingxing Teng,
Yanke Liang,
J. Hatcher,
Zhengnian Li,
Theresa D. Manz,
Brian J. Groendyke,
Wanyi Hu,
Yunju Nam,
Sandip Sengupta,
Hanna Cho,
I. Shin,
Michael P. Agius,
I. Ghobrial,
Michelle W. Ma,
Jianwei Che,
S. Buhrlage,
Taebo Sim,
N. Gray,
E. Fischer
|
7 |
2020 |
7
π
|
|
π
|
Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway
8 auth.
Sang-Eun Park,
Jeong-Mok Kim,
Ok-Hee Seok,
Hanna Cho,
B. Wadas,
Seon-Young Kim,
...
A. Varshavsky,
C. Hwang
|
7 |
2015 |
7
π
|
|
π¬
|
The N-Terminal Methionine of Cellular Proteins as a Degradation Signal
Heon Kim,
R. Kim,
Jang-Hyun Oh,
Hanna Cho,
A. Varshavsky,
C. Hwang
|
7 |
2014 |
7
π¬
|
|
π
|
Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors.
9 auth.
Arun K. Ghosh,
Lisa M. Swanson,
Hanna Cho,
S. Leshchenko,
K. A. Hussain,
Stephanie Kay,
...
D. Eric Walters,
Y. Koh,
H. Mitsuya
|
5 |
2005 |
5
π
|
|
π¬
|
Antitumor Effects and Mechanisms of AZD4547 on FGFR2-Deregulated Endometrial Cancer Cells
Yeonui Kwak,
Hanna Cho,
W. Hur,
Taebo Sim
|
4 |
2015 |
4
π¬
|
|
π¬
|
A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
Hojong Yoon,
Yeonui Kwak,
Seunghye Choi,
Hanna Cho,
N. Kim,
Taebo Sim
|
4 |
2016 |
4
π¬
|
|
π¬
|
Antiviral activity of UIC-PI, a novel inhibitor of the human immunodeficiency virus type 1 protease.
Arun K. Ghosh,
E. Pretzer,
Hanna Cho,
K. A. Hussain,
N. DΓΌzgΓΌneΕ
|
4 |
2002 |
4
π¬
|
|
π¬
|
Bis(oxazoline) derived cationic aqua complexes: highly effective catalysts for enantioselective Diels-Alder reactions.
Arun K. Ghosh,
Hanna Cho,
J. Cappiello
|
4 |
1998 |
4
π¬
|
