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Pharmacogenomics Knowledge for Personalized Medicine
8 auth.
Michelle Whirl‐Carrillo,
E. McDonagh,
J. Hebert,
L. Gong,
K. Sangkuhl,
C. Thorn,
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R. Altman,
T. Klein
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2012 |
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Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
101 auth.
Cayetano Pleguezuelos-Manzano,
Jens Puschhof,
Axel K M Rosendahl Huber,
Arne van Hoeck,
H. Wood,
Jason Nomburg,
Carino Gurjao,
F. Manders,
G. Dalmasso,
P. Stege,
F. Paganelli,
Maarten H. Geurts,
J. Beumer,
Tomohiro Mizutani,
Y. Miao,
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Reinier van der Linden,
S. van der Elst,
J. Ambrose,
P. Arumugam,
E. Baple,
M. Bleda,
F. Boardman-Pretty,
J. Boissiere,
C. Boustred,
H. Brittain,
M. Caulfield,
G. Chan,
C. Craig,
L. Daugherty,
A. de Burca,
A. Devereau,
G. Elgar,
R. Foulger,
T. Fowler,
P. Furió-Tarí,
J. Hackett,
D. Halai,
A. Hamblin,
S. Henderson,
J. Holman,
T. Hubbard,
K. Ibáñez,
R. Jackson,
L. J. Jones,
D. Kasperaviciute,
M. Kayikci,
L. Lahnstein,
L. Lawson,
S. Leigh,
I. Leong,
F. J. Lopez,
F. Maleady-Crowe,
J. Mason,
E. McDonagh,
L. Moutsianas,
M. Mueller,
N. Murugaesu,
A. Need,
C. Odhams,
C. Patch,
D. Perez-Gil,
D. Polychronopoulos,
J. Pullinger,
T. Rahim,
A. Rendon,
P. Riesgo-Ferreiro,
T. Rogers,
M. Ryten,
K. Savage,
K. Sawant,
R. Scott,
A. Siddiq,
A. Sieghart,
D. Smedley,
K. Smith,
A. Sosinsky,
W. Spooner,
H. E. Stevens,
A. Stuckey,
R. Sultana,
E. Thomas,
S. Thompson,
C. Tregidgo,
A. Tucci,
E. Walsh,
S. Watters,
M. Welland,
E. Williams,
K. Witkowska,
S. Wood,
M. Zarowiecki,
K. Garcia,
J. Top,
R. Willems,
M. Giannakis,
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P. Quirke,
M. Meyerson,
E. Cuppen,
R. van Boxtel,
H. Clevers
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9 |
2020 |
9
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Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process
27 auth.
K. Caudle,
T. Klein,
J. Hoffman,
D. Müller,
Michelle Whirl‐Carrillo,
L. Gong,
E. McDonagh,
K. Sangkuhl,
C. Thorn,
Matthias Schwab,
Matthias Schwab,
J. Agúndez,
R. Freimuth,
V. Huser,
M. Lee,
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M. M. Lee,
O. Iwuchukwu,
K. Crews,
S. Scott,
M. Wadelius,
J. Swen,
R. Tyndale,
C. Stein,
D. Roden,
M. Relling,
Marc S. Williams,
Samuel G. Johnson
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8 |
2014 |
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Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
35 auth.
M. Ghoussaini,
Edward Mountjoy,
M. Carmona,
Gareth Peat,
Ellen M. Schmidt,
Andrew Hercules,
Luca Fumis,
Alfredo Miranda,
D. Carvalho-Silva,
A. Buniello,
Tony Burdett,
J. Hayhurst,
Jarrod Baker,
Javier Ferrer,
Asier Gonzalez-Uriarte,
...
S. Jupp,
M. Karim,
Gautier Koscielny,
Sandra Machlitt-Northen,
Cinzia Malangone,
Z. Pendlington,
P. Roncaglia,
D. Suveges,
Daniel Wright,
Olga Vrousgou,
Eliseo Papa,
H. Parkinson,
J. MacArthur,
J. Todd,
J. Barrett,
J. Schwartzentruber,
D. G. Hulcoop,
D. Ochoa,
E. McDonagh,
I. Dunham
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8 |
2020 |
8
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PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels
22 auth.
A. Martin,
E. Williams,
R. Foulger,
S. Leigh,
L. Daugherty,
Olivia Niblock,
I. Leong,
Katherine R. Smith,
Oleg Gerasimenko,
Eik Haraldsdottir,
...
E. Thomas,
R. Scott,
E. Baple,
A. Tucci,
H. Brittain,
A. de Burca,
K. Ibáñez,
D. Kasperaviciute,
D. Smedley,
M. Caulfield,
A. Rendon,
E. McDonagh
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8 |
2019 |
8
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Open Targets Platform: supporting systematic drug–target identification and prioritisation
32 auth.
D. Ochoa,
Andrew Hercules,
M. Carmona,
D. Suveges,
Asier Gonzalez-Uriarte,
Cinzia Malangone,
Alfredo Miranda,
Luca Fumis,
D. Carvalho-Silva,
M. Spitzer,
Jarrod Baker,
Javier Ferrer,
A. Raies,
Olesya Razuvayevskaya,
Adam Faulconbridge,
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Eirini Petsalaki,
P. Mutowo,
Sandra Machlitt-Northen,
Gareth Peat,
Elaine McAuley,
C. Ong,
Edward Mountjoy,
M. Ghoussaini,
A. Pierleoni,
Eliseo Papa,
M. Pignatelli,
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M. Karim,
J. Schwartzentruber,
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I. Dunham,
E. McDonagh
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8 |
2020 |
8
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The 100 000 Genomes Project: bringing whole genome sequencing to the NHS
29 auth.
C. Turnbull,
R. Scott,
E. Thomas,
L. Jones,
N. Murugaesu,
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D. Halai,
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C. Craig,
A. Hamblin,
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C. Patch,
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K. Smith,
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A. Martin,
A. Sosinsky,
E. McDonagh,
R. Sultana,
Michael Mueller,
D. Smedley,
A. Toms,
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M. Bale,
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A. Rendon,
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M. Caulfield
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8 |
2018 |
8
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The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
34 auth.
D. Ochoa,
Andrew Hercules,
M. Carmona,
D. Suveges,
Jarrod Baker,
Cinzia Malangone,
Irene Lopez,
Alfredo Miranda,
C. Cruz-Castillo,
Luca Fumis,
Manuel Bernal-Llinares,
Kirill Tsukanov,
Helena Cornu,
Konstantinos D. Tsirigos,
Olesya Razuvayevskaya,
...
A. Buniello,
Jeremy Schwartzentruber,
M. Karim,
Bruno Ariano,
Ricardo Esteban Martinez Osorio,
Javier Ferrer,
X. Ge,
Sandra Machlitt-Northen,
Asier Gonzalez-Uriarte,
Shyamasree Saha,
Santosh Tirunagari,
C. Mehta,
J. M. Roldan-Romero,
S. Horswell,
Sarah Young,
M. Ghoussaini,
D. G. Hulcoop,
I. Dunham,
E. McDonagh
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7 |
2022 |
7
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From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource.
E. McDonagh,
Michelle Whirl‐Carrillo,
Yael Garten,
R. Altman,
T. Klein
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7 |
2011 |
7
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The 100,000 Genomes Pilot on Rare Disease Diagnosis in Healthcare − A Preliminary Report
195 auth.
D. Smedley,
Katherine R. Smith,
A. Martin,
Ellen Thomas,
E. McDonagh,
Valentina Cipriani,
J. Ellingford,
G. Arno,
A. Tucci,
J. Vandrovcova,
G. Chan,
H. Williams,
T. Ratnaike,
Wei Wei,
K. Stirrups,
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K. Ibáñez,
L. Moutsianas,
M. Wielscher,
A. Need,
M. Barnes,
L. Vestito,
J. Buchanan,
S. Wordsworth,
Sofie Ashford,
Karola Rehmström,
Emily Li,
G. Fuller,
Philip Twiss,
O. Spasic-Boskovic,
S. Halsall,
R. Floto,
K. Poole,
A. Wagner,
S. Mehta,
M. Gurnell,
N. Burrows,
R. James,
C. Penkett,
Eleanor F. Dewhurst,
S. Gräf,
R. Mapeta,
Mary A. Kasanicki,
A. Haworth,
H. Savage,
M. Babcock,
M. G. Reese,
M. Bale,
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C. Boustred,
H. Brittain,
A. de Burca,
M. Bleda,
A. Devereau,
D. Halai,
Eik Haraldsdottir,
Z. Hyder,
D. Kasperaviciute,
C. Patch,
D. Polychronopoulos,
Angela Matchan,
R. Sultana,
M. Ryten,
A. L. T. Tavares,
C. Tregidgo,
C. Turnbull,
M. Welland,
S. Wood,
Catherine Snow,
E. Williams,
S. Leigh,
R. Foulger,
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Olivia Niblock,
I. Leong,
C. Wright,
J. Davies,
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James Welch,
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D. Josifova,
S. Mohammed,
L. Robert,
Sarah V. Rose,
D. Ruddy,
R. Sarkany,
G. Say,
A. Shaw,
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Gavin Burns,
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Michael Simpson,
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J. Clayton-Smith,
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Huw B. Thomas,
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M. Michaelides,
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G. Gorman,
R. Horvath,
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Robert W. Taylor,
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Katrina Newland,
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J. Polke,
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C. Campbell,
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K. Gibson,
Nils Koelling,
T. Lester,
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John M. Taylor,
P. Cacheiro,
Julius O. B. Jacobsen,
E. Seaby,
V. Davison,
L. Chitty,
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M. Bitner-Glindzicz,
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H. Houlden,
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William Newman,
S. Rahman,
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Jenny C. Taylor,
A. Webster,
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T. Fowler,
A. Rendon,
M. Caulfield
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2021 |
7
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The Chemokine Receptor CXCR3 Is Degraded following Internalization and Is Replenished at the Cell Surface by De Novo Synthesis of Receptor1
9 auth.
A. Meiser,
A. Mueller,
E. Wise,
E. McDonagh,
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N. Saran,
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P. Clark,
T. Williams,
J. Pease
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Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA‐B) genotype and allopurinol dosing: 2015 update
13 auth.
Yoshiro Saito,
L. Stamp,
K. Caudle,
Michael S. Hershfield,
E. McDonagh,
J. T. Callaghan,
W. Tassaneeyakul,
T. Mushiroda,
N. Kamatani,
Barry R. Goldspiel,
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Elizabeth J. Phillips,
T. Klein,
Ming Ta Michael Lee
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