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🦁
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Organoid Models of Human and Mouse Ductal Pancreatic Cancer
74 auth.
S. Boj,
C. Hwang,
C. Hwang,
Lindsey A. Baker,
Lindsey A. Baker,
I. I. C. Chio,
I. I. C. Chio,
Dannielle D. Engle,
Dannielle D. Engle,
V. Corbo,
V. Corbo,
M. Jager,
M. Ponz-Sarvisé,
M. Ponz-Sarvisé,
Hervé Tiriac,
...
Hervé Tiriac,
M. Spector,
M. Spector,
A. Gračanin,
Tobiloba E. Oni,
Tobiloba E. Oni,
Tobiloba E. Oni,
Kenneth H. Yu,
R. Boxtel,
Meritxell Huch,
Keith D. Rivera,
John P. Wilson,
Michael E. Feigin,
Michael E. Feigin,
D. Öhlund,
D. Öhlund,
Abram Handly-Santana,
Abram Handly-Santana,
C. Ardito-Abraham,
C. Ardito-Abraham,
M. Ludwig,
M. Ludwig,
Ela Elyada,
Ela Elyada,
Brinda Alagesan,
Brinda Alagesan,
Brinda Alagesan,
Giulia Biffi,
Giulia Biffi,
Georgi N. Yordanov,
Georgi N. Yordanov,
Bethany Delcuze,
Bethany Delcuze,
Brianna Creighton,
Brianna Creighton,
K. Wright,
K. Wright,
Youngkyu Park,
Youngkyu Park,
F. Morsink,
I. Molenaar,
I. Rinkes,
E. Cuppen,
Yi Hao,
Ying-yu Jin,
I. Nijman,
C. Iacobuzio-Donahue,
S. Leach,
D. Pappin,
Molly Hammell,
D. Klimstra,
O. Basturk,
R. Hruban,
G. Offerhaus,
R. Vries,
H. Clevers,
D. Tuveson,
D. Tuveson,
D. Tuveson
|
10 |
2015 |
10
🦁
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|
🐜
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A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
31 auth.
Norman Sachs,
J. Ligt,
O. Kopper,
E. Gogola,
G. Bounova,
F. Weeber,
Anjali Vanita Balgobind,
K. Wind,
A. Gračanin,
H. Begthel,
J. Korving,
R. Boxtel,
A. Duarte,
Daphne Lelieveld,
A. Hoeck,
...
Robert F. Ernst,
Francis Blokzijl,
I. Nijman,
M. Hoogstraat,
M. Ven,
D. Egan,
Vittoria Zinzalla,
J. Moll,
S. Boj,
E. Voest,
L. Wessels,
P. Diest,
S. Rottenberg,
R. Vries,
E. Cuppen,
H. Clevers
|
10 |
2018 |
10
🐜
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|
🐜
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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
14 auth.
Meritxell Huch,
C. Dorrell,
S. Boj,
J. V. Es,
Vivian S. W. Li,
M. Wetering,
Toshiro Sato,
K. Hamer,
Nobuo Sasaki,
M. Finegold,
...
Annelise Haft,
R. Vries,
M. Grompe,
H. Clevers
|
10 |
2013 |
10
🐜
|
|
🐜
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Long‐term expanding human airway organoids for disease modeling
48 auth.
Norman Sachs,
A. Papaspyropoulos,
D. Z. Zomer-van Ommen,
Inha Heo,
L. Böttinger,
Dymph Klay,
F. Weeber,
Guizela Huelsz-Prince,
Nino Iakobachvili,
G. Amatngalim,
J. Ligt,
A. Hoeck,
N. Proost,
M. Viveen,
A. Lyubimova,
...
Luc Teeven,
Sepideh Derakhshan,
J. Korving,
H. Begthel,
J. Dekkers,
Kuldeep Kumawat,
E. Ramos,
Matthijs FM Oosterhout,
G. Offerhaus,
Dominique J Wiener,
E. P. Olimpio,
K. Dijkstra,
E. Smit,
Maarten Linden,
S. Jaksani,
M. Ven,
J. Jonkers,
A. Rios,
E. Voest,
Coline HM Moorsel,
C. Ent,
E. Cuppen,
A. Oudenaarden,
F. Coenjaerts,
L. Meyaard,
L. Bont,
P. Peters,
S. Tans,
J. S. Zon,
S. Boj,
R. Vries,
J. Beekman,
H. Clevers
|
9 |
2019 |
9
🐜
|
|
🐜
|
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
19 auth.
Meritxell Huch,
P. Bonfanti,
S. Boj,
Toshiro Sato,
Cindy J. M. Loomans,
M. van de Wetering,
M. Sojoodi,
Vivian S. W. Li,
Jurian Schuijers,
A. Gračanin,
...
F. Ringnalda,
H. Begthel,
K. Hamer,
J. Mulder,
J. van Es,
E. D. de Koning,
R. Vries,
H. Heimberg,
H. Clevers
|
9 |
2013 |
9
🐜
|
|
🐜
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Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
7 auth.
Laura Broutier,
Amanda Andersson-Rolf,
C. Hindley,
S. Boj,
H. Clevers,
B. Koo,
...
Meritxell Huch
|
9 |
2016 |
9
🐜
|
|
🐜
|
Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene
9 auth.
E. Pearson,
S. Boj,
A. Steele,
T. Barrett,
K. Stals,
J. Shield,
...
S. Ellard,
J. Ferrer,
A. Hattersley
|
8 |
2007 |
8
🐜
|
|
🐜
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Pancreatic cancer organoids recapitulate disease and allow personalized drug screening
29 auth.
E. Driehuis,
E. Driehuis,
A. Hoeck,
A. Hoeck,
Kat S. Moore,
S. Kolders,
Sigrid Kolders,
Hayley E. Francies,
M. Gulersonmez,
E. Stigter,
B. Burgering,
Veerle Geurts,
Veerle Geurts,
A. Gračanin,
G. Bounova,
...
F. Morsink,
R. Vries,
S. Boj,
J. V. Es,
J. V. Es,
G. Offerhaus,
O. Kranenburg,
M. Garnett,
L. Wessels,
Edwin Cuppen,
Edwin Cuppen,
L. Brosens,
H. Clevers,
Hans Clevers
|
8 |
2019 |
8
🐜
|
|
🦁
|
A transcription factor regulatory circuit in differentiated pancreatic cells
S. Boj,
M. Párrizas,
M. Maestro,
J. Ferrer
|
8 |
2001 |
8
🦁
|
|
🐜
|
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
17 auth.
Z. Steinhart,
Z. Pavlovic,
M. Chandrashekhar,
Traver Hart,
Xiaowei Wang,
Xiaoyu Zhang,
M. Robitaille,
K. Brown,
S. Jaksani,
R. Overmeer,
...
S. Boj,
Jarrett J. Adams,
James G. Pan,
H. Clevers,
S. Sidhu,
J. Moffat,
S. Angers
|
8 |
2016 |
8
🐜
|
|
🐜
|
A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal
11 auth.
J. van Es,
A. Haegebarth,
P. Kujala,
S. Itzkovitz,
B. Koo,
S. Boj,
...
J. Korving,
Maaike van den Born,
A. van Oudenaarden,
S. Robine,
H. Clevers
|
8 |
2012 |
8
🐜
|
|
🦁
|
Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand
15 auth.
S. Boj,
J. V. Es,
Meritxell Huch,
Vivian S. W. Li,
Anabel José,
P. Hatzis,
M. Mokry,
A. Haegebarth,
M. V. D. Born,
P. Chambon,
...
P. Voshol,
Y. Dor,
E. Cuppen,
C. Fillat,
H. Clevers
|
7 |
2012 |
7
🦁
|
|
🐜
|
Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas.
10 auth.
M. Maestro,
S. Boj,
R. Luco,
C. Pierreux,
J. Cabedo,
J. Servitja,
...
M. German,
G. Rousseau,
F. Lemaigre,
J. Ferrer
|
7 |
2003 |
7
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|
