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Title Level Year L/Y
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
C. Gorman, L. Moffat, B. Howard
12 1982 12
1982
High-efficiency transformation of mammalian cells by plasmid DNA.
Claudia A. Chen, H. Okayama
12 1987 12
1987
Correlation between Protein and mRNA Abundance in Yeast
S. Gygi, Yvan Rochon, B. Robert Franza, R. Aebersold
11 1999 11
1999
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
7 auth. Jo A. Forsythe, B. Jiang, N. Iyer, F. Agani, S. Leung, R. Koos, ... G. Semenza
11 1996 11
1996
Firefly luciferase gene: structure and expression in mammalian cells
J. D. Wet, K. Wood, Marlene Deluca, D. Helinski, S. Subramani
11 1987 11
1987
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
G. Semenza, Guang-lei Wang
11 1992 11
1992
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product
G. Evan, G. Lewis, G. Ramsay, J. Bishop
11 1985 11
1985
Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion
7 auth. Steffen Jung, J. Aliberti, Petra Graemmel, M. Sunshine, G. Kreutzberg, A. Sher, ... D. Littman
11 2000 11
2000
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response
Ann-Hwee Lee, N. Iwakoshi, L. Glimcher
11 2003 11
2003
Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2
8 auth. A. Kobayashi, Moon-Il Kang, H. Okawa, Makiko Ohtsuji, Y. Zenke, T. Chiba, ... K. Igarashi, Masayuki Yamamoto
11 2004 11
2004
Transposable Elements: Targets for Early Nutritional Effects on Epigenetic Gene Regulation
R. Waterland, R. Jirtle
10 2003 10
2003
Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State
K. McCullough, J. Martindale, L. Klotz, T. Aw, N. Holbrook
10 2001 10
2001
Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress
14 auth. Maiko Ogata, S. Hino, A. Saito, Keisuke Morikawa, S. Kondo, Soshi Kanemoto, Tomohiko Murakami, M. Taniguchi, I. Tanii, K. Yoshinaga, ... Sadao Shiosaka, J. Hammarback, F. Urano, K. Imaizumi
10 2006 10
2006
Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms
M. Massari, C. Murre
10 2000 10
2000
CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms
9 auth. R. Parry, J. Chemnitz, K. Frauwirth, A. Lanfranco, Inbal Braunstein, Sumire V. Kobayashi, ... P. Linsley, C. Thompson, J. Riley
10 2004 10
2004
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
9 auth. S. Lee, T. Pineau, J. Drago, Eric J. Lee, J. Owens, D. Kroetz, ... P. Fernández-Salguero, H. Westphal, F. Gonzalez
10 1995 10
1995
Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway
E. Jho, Tong Zhang, C. Domon, C. Joo, J. Freund, F. Costantini
10 2002 10
2002
c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism
C. Dang
10 1999 10
1999
Inhibition of Macroautophagy Triggers Apoptosis
13 auth. P. Boya, R. González-Polo, N. Casares, J. Perfettini, P. Dessen, N. Larochette, D. Métivier, D. Meley, S. Souquere, T. Yoshimori, ... G. Pierron, P. Codogno, G. Kroemer
10 2005 10
2005
Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers
H. Schaeffer, M. J. Weber
10 1999 10
1999
Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
C. T. Guy, R. Cardiff, W. Muller
10 1992 10
1992