|
🐜
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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
18 auth.
Traver Hart,
M. Chandrashekhar,
Michael Aregger,
Z. Steinhart,
K. Brown,
G. Macleod,
Monika Miś,
Michal Zimmermann,
Amélie Fradet-Turcotte,
Song Sun,
...
P. Mero,
P. Dirks,
S. Sidhu,
F. Roth,
Olivia S. Rissland,
D. Durocher,
S. Angers,
J. Moffat
|
10 |
2015 |
10
🐜
|
|
🦁
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Wnt signaling in development and tissue homeostasis
Z. Steinhart,
S. Angers
|
9 |
2018 |
9
🦁
|
|
🐜
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Test performance evaluation of SARS-CoV-2 serological assays
71 auth.
Jeffrey D. Whitman,
J. Hiatt,
C. Mowery,
B. Shy,
Ruby Yu,
Tori N. Yamamoto,
Ujjwal Rathore,
Gregory M. Goldgof,
Caroline Whitty,
J. Woo,
Antonia E. Gallman,
T. Miller,
Andrew G Levine,
David N. Nguyen,
Sagar P Bapat,
...
J. Balcerek,
Sophia A. Bylsma,
A. M. Lyons,
Stacy Li,
A. Wong,
Eva M. Gillis-Buck,
Z. Steinhart,
Youjin V. Lee,
Ryan Apathy,
Mitchell J. Lipke,
Jennifer A. Smith,
Tina Zheng,
I. Boothby,
E. Isaza,
Jackie Chan,
Dante Acenas,
Jinwoo Lee,
Trisha A. Macrae,
Than S. Kyaw,
David Wu,
Dianna L. Ng,
W. Gu,
V. York,
H. Eskandarian,
Perri C. Callaway,
L. Warrier,
M. E. Moreno,
J. Levan,
L. Torres,
Lila A. Farrington,
R. Loudermilk,
Kanishka Koshal,
K. Zorn,
W. García-Beltrán,
Diane Yang,
M. Astudillo,
B. Bernstein,
J. Gelfand,
E. Ryan,
R. Charles,
A. Iafrate,
J. Lennerz,
Steve Miller,
C. Chiu,
S. Stramer,
M. Wilson,
A. Manglik,
N. Krogan,
Mark S. Anderson,
J. Cyster,
J. Ernst,
A. Wu,
K. Lynch,
C. Bern,
P. Hsu,
A. Marson
|
8 |
2020 |
8
🐜
|
|
🦁
|
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
17 auth.
Z. Steinhart,
Z. Pavlovic,
M. Chandrashekhar,
Traver Hart,
Xiaowei Wang,
Xiaoyu Zhang,
M. Robitaille,
K. Brown,
S. Jaksani,
R. Overmeer,
...
S. Boj,
Jarrett J. Adams,
James G. Pan,
H. Clevers,
S. Sidhu,
J. Moffat,
S. Angers
|
8 |
2016 |
8
🦁
|
|
🐜
|
Test performance evaluation of SARS-CoV-2 serological assays
72 auth.
Jeffrey D. Whitman,
J. Hiatt,
C. Mowery,
B. Shy,
Ruby Yu,
Tori N. Yamamoto,
Ujjwal Rathore,
Gregory M. Goldgof,
Caroline Whitty,
J. Woo,
Antonia E. Gallman,
T. Miller,
Andrew G Levine,
David N. Nguyen,
Sagar P Bapat,
...
J. Balcerek,
Sophia A. Bylsma,
A. M. Lyons,
Stacy Li,
A. Wong,
Eva M. Gillis-Buck,
Z. Steinhart,
Youjin V. Lee,
Ryan Apathy,
Mitchell J. Lipke,
Jennifer A. Smith,
Tina Zheng,
I. Boothby,
E. Isaza,
Jackie Chan,
Dante Acenas,
Jinwoo Lee,
Trisha A. Macrae,
Than S. Kyaw,
David Wu,
Dianna L. Ng,
W. Gu,
V. York,
H. Eskandarian,
Perri C. Callaway,
L. Warrier,
M. E. Moreno,
J. Levan,
L. Torres,
Lila A. Farrington,
R. Loudermilk,
Kanishka Koshal,
K. Zorn,
W. García-Beltrán,
Diane Yang,
M. Astudillo,
B. Bernstein,
J. Gelfand,
E. Ryan,
R. Charles,
A. Iafrate,
J. Lennerz,
Steve Miller,
C. Chiu,
S. Stramer,
M. Wilson,
A. Manglik,
Chun Jimmie Ye,
N. Krogan,
Mark S. Anderson,
J. Cyster,
J. Ernst,
A. Wu,
K. Lynch,
C. Bern,
P. Hsu,
A. Marson
|
7 |
2020 |
7
🐜
|
|
🐜
|
CRISPR activation and interference screens decode stimulation responses in primary human T cells
9 auth.
Ralf Schmidt,
Z. Steinhart,
Madeline Layeghi,
Jacob W. Freimer,
R. Bueno,
V. Nguyen,
...
Franziska Blaeschke,
Chun Jimmie Ye,
A. Marson
|
7 |
2022 |
7
🐜
|
|
🐜
|
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
17 auth.
G. Macleod,
Danielle A. Bozek,
N. Rajakulendran,
V. Monteiro,
Moloud Ahmadi,
Z. Steinhart,
M. Kushida,
Helen Yu,
F. Coutinho,
F. Cavalli,
...
Ian J. Restall,
X. Hao,
Traver Hart,
H. A. Luchman,
S. Weiss,
P. Dirks,
S. Angers
|
7 |
2019 |
7
🐜
|
|
🐜
|
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
18 auth.
L. Aubert,
N. Nandagopal,
Z. Steinhart,
G. Lavoie,
Sami Nourreddine,
Jacob M. Berman,
M. Saba-El-Leil,
David Papadopoli,
Sichun Lin,
Traver Hart,
...
G. Macleod,
I. Topisirovic,
L. Gaboury,
C. Fahrni,
D. Schramek,
S. Meloche,
S. Angers,
Philippe P Roux
|
7 |
2020 |
7
🐜
|
|
🐬
|
Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay
Melissa V. Gammons,
T. Rutherford,
Z. Steinhart,
S. Angers,
M. Bienz
|
6 |
2016 |
6
🐬
|
|
🐜
|
Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice
15 auth.
Yuyong Tao,
Monika Miś,
Levi L Blazer,
M. Ustav,
Z. Steinhart,
Rony Chidiac,
Elli Kubarakos,
Siobhan O’Brien,
Xiaomei Wang,
N. Jarvik,
...
N. Patel,
Jarrett J. Adams,
J. Moffat,
S. Angers,
S. Sidhu
|
5 |
2019 |
5
🐜
|
|
🐜
|
Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins
16 auth.
I. Červenka,
Jana Valnohova,
Ondřej Bernatík,
J. Harnoš,
Matěj Rádsetoulal,
K. Šedová,
Kateřina Hanáková,
D. Potěšil,
M. Sedláčková,
A. Salašová,
...
Z. Steinhart,
S. Angers,
G. Schulte,
A. Hampl,
Z. Zdráhal,
V. Bryja
|
5 |
2016 |
5
🐜
|
