|
🐜
|
Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics.
29 auth.
M. Maier,
M. Jayaraman,
S. Matsuda,
Ju Liu,
Scott A. Barros,
W. Querbes,
Ying K. Tam,
S. Ansell,
Varun Kumar,
June Qin,
Xuemei Zhang,
Qianfan Wang,
Sue Panesar,
R. Hutabarat,
Mary Carioto,
...
J. Hettinger,
P. Kandasamy,
David Butler,
K. G. Rajeev,
Bo Pang,
K. Charissé,
K. Fitzgerald,
B. Mui,
Xinyao Du,
P. Cullis,
T. D. Madden,
M. Hope,
M. Manoharan,
Akin Akinc
|
8 |
2013 |
8
🐜
|
|
🐜
|
Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates
24 auth.
Jayaprakash K Nair,
H. Attarwala,
A. Sehgal,
Qianfan Wang,
Krishna C. Aluri,
Xuemei Zhang,
Minggeng Gao,
Ju Liu,
Ramesh Indrakanti,
Sally Schofield,
...
Philip Kretschmer,
Christopher R Brown,
Swati Gupta,
J. Willoughby,
Julie A. Boshar,
V. Jadhav,
K. Charissé,
Tracy S. Zimmermann,
K. Fitzgerald,
M. Manoharan,
K. G. Rajeev,
Akin Akinc,
R. Hutabarat,
M. Maier
|
7 |
2017 |
7
🐜
|
|
🐜
|
Characterization of Functional Excision Repair Cross-Complementation Group 1 Variants and Their Association with Lung Cancer Risk and Prognosis
12 auth.
Dianke Yu,
Xuemei Zhang,
Ju Liu,
P. Yuan,
W. Tan,
Yongli Guo,
...
T. Sun,
Dan Zhao,
Ming Yang,
Junniao Liu,
Bing-he Xu,
D. Lin
|
5 |
2008 |
5
🐜
|
|
🐜
|
Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalNAc-siRNA conjugates
34 auth.
Maja M. Janas,
Ivan Zlatev,
Ju Liu,
Yongfeng Jiang,
Scott A. Barros,
J. Sutherland,
Wendell P. Davis,
Jingxuan Liu,
Christopher R Brown,
Xiumin Liu,
M. Schlegel,
L. Blair,
Xuemei Zhang,
Biplab Das,
C. Tran,
...
Krishna C. Aluri,
Jing Li,
S. Agarwal,
Ramesh Indrakanti,
K. Charissé,
Jayaprakash K Nair,
S. Matsuda,
K. G. Rajeev,
Tracy S. Zimmermann,
L. Sepp-Lorenzino,
Yuanxin Xu,
Akin Akinc,
K. Fitzgerald,
A. Vaishnaw,
Peter Smith,
M. Manoharan,
V. Jadhav,
Jing-tao Wu,
M. Maier
|
5 |
2019 |
5
🐜
|
|
🐜
|
The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
38 auth.
S. Chong,
Sagar Agarwal,
S. Agarwal,
Krishna C. Aluri,
Michael Arciprete,
Christopher R Brown,
K. Charissé,
J. Cichocki,
K. Fitzgerald,
V. Goel,
Yongli Gu,
Dale C. Guenther,
B. Habtemariam,
Vasant Jadhav,
Maja M. Janas,
...
M. Jayaraman,
J. Kurz,
Jing Li,
Steven Liou,
Ju Liu,
Xiumin Liu,
Christopher Maclauchlin,
Martin E. Maier,
M. Manoharan,
Robin McDougall,
Jayaprakash K Nair,
D. Ramsden,
G. Robbie,
Karyn M. Schmidt,
Peter Smith,
Christopher S. Theile,
A. Vaishnaw,
S. Waldron,
Jing-tao Wu,
Yuanxin Xu,
Xuemei Zhang,
Ivan Zlatev,
Elena Castellanos-Rizaldos
|
5 |
2021 |
5
🐜
|
|
🦁
|
Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectrometry.
13 auth.
Ju Liu,
Jing Li,
C. Tran,
Krishna C. Aluri,
Xuemei Zhang,
Valerie A. Clausen,
Ivan Zlatev,
Li-Hua Guan,
S. Chong,
K. Charissé,
...
Jing-tao Wu,
Diana R Najarian,
Yuanxin Xu
|
5 |
2019 |
5
🦁
|
|
🐜
|
Discovery of a novel deaminated metabolite of a single-stranded oligonucleotide in vivo by mass spectrometry.
13 auth.
Jing Li,
Ju Liu,
Jennifer Enders,
Michael Arciprete,
C. Tran,
Krishna C. Aluri,
Li-Hua Guan,
Jonathan O’Shea,
Anna Bisbe,
K. Charissé,
...
Ivan Zlatev,
Diana R Najarian,
Yuanxin Xu
|
5 |
2019 |
5
🐜
|
|
🐜
|
Nonclinical Pharmacokinetics and Absorption, Distribution, Metabolism, and Excretion of Givosiran, the First Approved N-Acetylgalactosamine–Conjugated RNA Interference Therapeutic
15 auth.
Jing Li,
Ju Liu,
Xuemei Zhang,
Valerie A. Clausen,
C. Tran,
Michael Arciprete,
Qianfan Wang,
Carrie Rocca,
Li-Hua Guan,
Guodong Zhang,
...
Diana R Najarian,
Yuanxin Xu,
Peter Smith,
Jing-tao Wu,
S. Chong
|
4 |
2021 |
4
🐜
|
|
🐜
|
Exposure to siRNA-GalNAc Conjugates in Systems of the Standard Test Battery for Genotoxicity.
8 auth.
Maja M. Janas,
Yongfeng Jiang,
Rick Duncan,
Antoinette N Hayes,
Ju Liu,
Pia V Kasperkovitz,
...
M. Placke,
Scott A. Barros
|
4 |
2016 |
4
🐜
|
