|
🐜
|
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
64 auth.
Hui Gao,
Joshua M. Korn,
S. Ferretti,
John E Monahan,
Youzhen Wang,
Mallika Singh,
Chao Zhang,
C. Schnell,
Guizhi Yang,
Yun Zhang,
O Alejandro Balbin,
S. Barbe,
H. Cai,
F. Casey,
S. Chatterjee,
...
Derek Y Chiang,
S. Chuai,
Shawn Cogan,
Scott D Collins,
Ernesta Dammassa,
N. Ebel,
M. Embry,
J. Green,
A. Kauffmann,
C. Kowal,
Rebecca J Leary,
J. Lehár,
Ying Liang,
Alice T. Loo,
Edward G. Lorenzana,
E. Robert McDonald,
Margaret E McLaughlin,
J. Merkin,
R. Meyer,
Tara L Naylor,
M. Patawaran,
Anupama Reddy,
Claudia Röelli,
D. Ruddy,
Fernando Salangsang,
F. Santacroce,
Angad P Singh,
Yan Tang,
W. Tinetto,
Sonja Tobler,
Roberto Velazquez,
K. Venkatesan,
Fabian Von Arx,
Hui Qin Wang,
Zongyao Wang,
M. Wiesmann,
D. Wyss,
Fiona Xu,
H. Bitter,
P. Atadja,
E. Lees,
F. Hofmann,
E. Li,
N. Keen,
R. Cozens,
M. Jensen,
N. Pryer,
J. Williams,
W. Sellers
|
10 |
2015 |
10
🐜
|
|
🐜
|
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition
31 auth.
O. Weigert,
A. Lane,
L. Bird,
Nadja Kopp,
B. Chapuy,
Diederik van Bodegom,
A. Toms,
Sachie Marubayashi,
A. Christie,
M. Mckeown,
Ronald M. Paranal,
J. Bradner,
A. Yoda,
C. Gaul,
Eric Vangrevelinghe,
...
Vincent Romanet,
M. Murakami,
R. Tiedt,
N. Ebel,
Emeline Evrot,
A. de Pover,
C. Regnier,
D. Erdmann,
F. Hofmann,
M. Eck,
S. Sallan,
R. Levine,
A. Kung,
F. Baffert,
Thomas Radimerski,
D. Weinstock
|
7 |
2011 |
7
🐜
|
|
🐜
|
CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.
38 auth.
S. Meyer,
Matthew D. Keller,
Sophia Chiu,
Priya Koppikar,
O. Guryanova,
Franck Rapaport,
Ke Xu,
K. Manova,
D. Pankov,
R. O'reilly,
M. Kleppe,
A. McKenney,
A. Shih,
K. Shank,
Jihae Ahn,
...
E. Papalexi,
B. Spitzer,
N. Socci,
A. Viale,
E. Mandon,
N. Ebel,
R. Andraos,
Joëlle Rubert,
Ernesta Dammassa,
Vincent Romanet,
A. Dölemeyer,
Michael Zender,
Melanie Heinlein,
R. Rampal,
R. Weinberg,
R. Hoffman,
W. Sellers,
F. Hofmann,
M. Murakami,
F. Baffert,
C. Gaul,
Thomas Radimerski,
R. Levine
|
7 |
2015 |
7
🐜
|
|
🐜
|
Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.
41 auth.
Shuo-chieh Wu,
Loretta S. Li,
Nadja Kopp,
J. Montero,
B. Chapuy,
A. Yoda,
A. Christie,
Huiyun Liu,
A. Christodoulou,
Diederik van Bodegom,
Jordy C. G. van der Zwet,
Jacob V. Layer,
Trevor Tivey,
A. Lane,
J. Ryan,
...
S. Ng,
D. DeAngelo,
R. Stone,
D. Steensma,
M. Wadleigh,
M. Harris,
E. Mandon,
N. Ebel,
R. Andraos,
Vincent Romanet,
A. Dölemeyer,
Dario Sterker,
Michael Zender,
S. Rodig,
M. Murakami,
F. Hofmann,
F. Kuo,
M. Eck,
L. Silverman,
S. Sallan,
A. Letai,
F. Baffert,
Eric Vangrevelinghe,
Thomas Radimerski,
C. Gaul,
D. Weinstock
|
6 |
2015 |
6
🐜
|
|
🐜
|
In vitro uptake evaluation in Caco-2 cells and in vivo results in diabetic rats of insulin-loaded PLGA nanoparticles.
12 auth.
N. Reix,
A. Parat,
E. Seyfritz,
Remmelt Van der Werf,
V. Epure,
N. Ebel,
...
L. Danicher,
E. Marchioni,
N. Jeandidier,
M. Pinget,
Y. Frere,
S. Sigrist
|
6 |
2012 |
6
🐜
|
|
🐜
|
JAK1/2 and Pan-Deacetylase Inhibitor Combination Therapy Yields Improved Efficacy in Preclinical Mouse Models of JAK2V617F-Driven Disease
14 auth.
Emeline Evrot,
N. Ebel,
Vincent Romanet,
Claudia Roelli,
R. Andraos,
Zhiyan Qian,
A. Dölemeyer,
Ernesta Dammassa,
Dario Sterker,
R. Cozens,
...
F. Hofmann,
M. Murakami,
F. Baffert,
Thomas Radimerski
|
6 |
2013 |
6
🐜
|
|
🐜
|
Improved Efficacy Upon Combined JAK1/2 and Pan-Deacetylase Inhibition Using Ruxolitinib (INC424) and Panobinostat (LBH589) in Preclinical Mouse Models of JAK2V617F-Driven Disease
9 auth.
F. Baffert,
Emeline Evrot,
N. Ebel,
Claudia Roelli,
R. Andraos,
Zhiyan Qian,
...
Vincent Romanet,
M. Murakami,
Thomas Radimerski
|
4 |
2011 |
4
🐜
|
|
🐜
|
High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells.
19 auth.
Thomas Horn,
S. Ferretti,
N. Ebel,
Angela Tam,
Samuel Ho,
Fred Harbinski,
Ali Farsidjani,
Matthew Zubrowski,
W. Sellers,
R. Schlegel,
...
D. Porter,
E. Morris,
J. Wuerthner,
S. Jeay,
J. Greshock,
Ensar Halilovic,
L. Garraway,
G. Caponigro,
J. Lehár
|
4 |
2016 |
4
🐜
|
|
🐜
|
Genetic resistance to JAK 2 enzymatic inhibitors is overcome by HSP 90 inhibition
31 auth.
O. Weigert,
A. Lane,
L. Bird,
Nadja Kopp,
B. Chapuy,
D. Bodegom,
A. Toms,
Sachie Marubayashi,
A. Christie,
M. Mckeown,
Ronald M. Paranal,
J. Bradner,
A. Yoda,
C. Gaul,
Eric Vangrevelinghe,
...
Vincent Romanet,
M. Murakami,
R. Tiedt,
N. Ebel,
Emeline Evrot,
A. Pover,
C. Regnier,
D. Erdmann,
F. Hofmann,
M. Eck,
S. Sallan,
R. Levine,
A. Kung,
F. Baffert,
Thomas Radimerski,
D. Weinstock
|
4 |
2012 |
4
🐜
|
|
🐜
|
Role of chemokine signaling pathways in pancreatic islet rejection during allo- and xenotransplantation.
11 auth.
S. Sigrist,
N. Ebel,
A. Langlois,
Domenico Bosco,
Christian Toso,
C. Kleiss,
...
K. Mandes,
Thierry Berney,
M. Pinget,
A. Belcourt,
Laurence Kessler
|
4 |
2005 |
4
🐜
|
