|
π
|
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
47 auth.
William E. Dowdle,
B. Nyfeler,
Jane Nagel,
Robert A. Elling,
Shanming Liu,
E. Triantafellow,
Suchithra Menon,
Zuncai Wang,
Ayako Honda,
G. Pardee,
John Cantwell,
Catherine Luu,
Ivan Cornella-Taracido,
Edmund Harrington,
Peter Fekkes,
...
Hong Lei,
Qing Fang,
M. E. Digan,
Debra Burdick,
Andrew F. Powers,
S. B. Helliwell,
Simon DβAquin,
Julie Bastien,
Henry Wang,
D. Wiederschain,
Jenny Kuerth,
Phil Bergman,
David Schwalb,
Jason R Thomas,
Savuth Ugwonali,
Fred Harbinski,
John A. Tallarico,
Christopher J. Wilson,
V. Myer,
Jeffery A. Porter,
D. Bussiere,
P. Finan,
Mark A. Labow,
Xiaohong Mao,
Lawrence G. Hamann,
Brendan D. Manning,
Reginald A. Valdez,
Thomas Nicholson,
M. Schirle,
Mark Knapp,
E. P. Keaney,
Leon O. Murphy
|
9 |
2014 |
9
π
|
|
π
|
TDP-43 represses cryptic exon inclusion in the FTDβALS gene UNC13A
35 auth.
X. R. Ma,
M. Prudencio,
Y. Koike,
Sarat C. Vatsavayai,
Garam Kim,
Fred Harbinski,
Adam Briner,
Caitlin M. Rodriguez,
Caiwei Guo,
T. Akiyama,
H. B. Schmidt,
Beryl B. Cummings,
David W. Wyatt,
K. Kurylo,
Georgiana Miller,
...
S. Mekhoubad,
Nathan A. Sallee,
Gemechu Mekonnen,
Laura R. Ganser,
Jack D. Rubien,
Karen R. Jansen-West,
C. Cook,
Sarah R Pickles,
B. Oskarsson,
N. Graff-Radford,
B. Boeve,
D. Knopman,
R. Petersen,
D. Dickson,
J. Shorter,
Sua Myong,
Eric M. Green,
W. Seeley,
L. Petrucelli,
A. Gitler
|
8 |
2021 |
8
π
|
|
π
|
Novel arylsulfoanilide-oxindole hybrid as an anticancer agent that inhibits translation initiation.
10 auth.
A. Natarajan,
Yuhong Guo,
Fred Harbinski,
Yun-Hua Fan,
Han Chen,
L. Luus,
...
Jana Diercks,
H. Aktas,
M. Chorev,
J. Halperin
|
7 |
2004 |
7
π
|
|
π¦
|
Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth.
24 auth.
Fred Harbinski,
V. Craig,
Sneha Sanghavi,
D. Jeffery,
Lijuan Liu,
K. Sheppard,
S. Wagner,
C. Stamm,
A. Buness,
C. ChatenayβRivauday,
...
Yao Yao,
F. He,
Chris X. Lu,
V. Guagnano,
T. Metz,
P. Finan,
F. Hofmann,
W. Sellers,
Jeffrey A. Porter,
V. Myer,
D. GrausβPorta,
Christopher J. Wilson,
A. Buckler,
R. Tiedt
|
6 |
2012 |
6
π¦
|
|
π
|
Chemical Genetics Identify eIF2Ξ± Kinase Heme Regulated Inhibitor as Anti-Cancer Target
12 auth.
Ting Chen,
D. Ozel,
Yuan Qiao,
Fred Harbinski,
Limo Chen,
S. Denoyelle,
...
Xiaoying He,
N. Zvereva,
J. Supko,
M. Chorev,
J. Halperin,
B. Aktas
|
6 |
2011 |
6
π
|
|
π
|
3,3-diaryl-1,3-dihydroindol-2-ones as antiproliferatives mediated by translation initiation inhibition.
9 auth.
A. Natarajan,
Yun-Hua Fan,
Han Chen,
Yuhong Guo,
J. Iyasere,
Fred Harbinski,
...
W. Christ,
H. Aktas,
J. Halperin
|
6 |
2004 |
6
π
|
|
π
|
Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39.
30 auth.
F. Bassilana,
Adam Carlson,
Jennifer Dasilva,
Bianka L. Grosshans,
Solange Vidal,
V. Beck,
Barbara Wilmeringwetter,
Luis A Llamas,
Todd B Showalter,
P. Rigollier,
Aaron Bourret,
Arun Ramamurthy,
Xu Wu,
Fred Harbinski,
Samantha Plonsky,
...
Lac Lee,
H. Ruffner,
P. Grandi,
M. Schirle,
J. Jenkins,
A. Sailer,
T. Bouwmeester,
Jeffrey A. Porter,
V. Myer,
P. Finan,
John A. Tallarico,
J. Kelleher,
K. Seuwen,
R. Jain,
Sarah J. Luchansky
|
5 |
2014 |
5
π
|
|
π
|
Synthesis and biological evaluation of thiazolidine-2,4-dione and 2,4-thione derivatives as inhibitors of translation initiation.
10 auth.
Han Chen,
Yun-Hua Fan,
A. Natarajan,
Yuhong Guo,
J. Iyasere,
Fred Harbinski,
...
L. Luus,
W. Christ,
H. Aktas,
J. Halperin
|
5 |
2004 |
5
π
|
|
π
|
Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays.
12 auth.
Pei-i Ho,
Kimberley Yue,
P. Pandey,
L. Breault,
Fred Harbinski,
Aaron J. Mcbride,
...
B. Webb,
J. Narahari,
N. Karassina,
K. Wood,
A. Hill,
D. Auld
|
5 |
2013 |
5
π
|
|
π
|
Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium.
9 auth.
Yun-Hua Fan,
Han Chen,
A. Natarajan,
Yuhong Guo,
Fred Harbinski,
J. Iyasere,
...
W. Christ,
H. Aktas,
J. Halperin
|
5 |
2004 |
5
π
|
