Network pharmacology: the next paradigm in drug discovery.
A. Hopkins
|
11 |
2008 |
11
2008
|
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
10 auth.
A. Degterev,
Zhihong Huang,
M. Boyce,
Yaqiao Li,
P. Jagtap,
N. Mizushima,
...
G. Cuny,
T. Mitchison,
M. Moskowitz,
Junying Yuan
|
11 |
2005 |
11
2005
|
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
22 auth.
S. Doll,
B. Proneth,
Y. Tyurina,
Elena Panzilius,
Sho Kobayashi,
Irina Ingold,
M. Irmler,
J. Beckers,
M. Aichler,
A. Walch,
...
H. Prokisch,
D. Trümbach,
G. Mao,
F. Qu,
H. Bayır,
J. Füllekrug,
C. Scheel,
W. Wurst,
Joel A. Schick,
V. Kagan,
J. Angeli,
M. Conrad
|
11 |
2017 |
11
2017
|
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
13 auth.
Jianzhao Liu,
Y. Yue,
Dali Han,
Xiao Wang,
Ye Fu,
Liang Zhang,
G. Jia,
Miao Yu,
Zhike Lu,
X. Deng,
...
Qing Dai,
Weizhong Chen,
Chuan He
|
11 |
2013 |
11
2013
|
Networking by small-molecule hormones in plant immunity.
C. Pieterse,
A. Leon-Reyes,
S. van der Ent,
Saskia C. M. Van Wees
|
11 |
2009 |
11
2009
|
Reconciling the chemistry and biology of reactive oxygen species.
C. Winterbourn
|
11 |
2008 |
11
2008
|
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
26 auth.
V. Kagan,
G. Mao,
F. Qu,
J. Angeli,
S. Doll,
C. S. Croix,
H. Dar,
B. Liu,
V. Tyurin,
V. Ritov,
A. Kapralov,
A. Amoscato,
Jianfei Jiang,
T. Anthonymuthu,
D. Mohammadyani,
...
Qin Yang,
B. Proneth,
J. Klein-Seetharaman,
Simon C Watkins,
I. Bahar,
J. Greenberger,
R. Mallampalli,
B. Stockwell,
Y. Tyurina,
M. Conrad,
H. Bayır
|
10 |
2017 |
10
2017
|
N6-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO
29 auth.
Guifang Jia,
G. Zheng,
Chengqi Yi,
Tomas Lindahl,
D. Anastasiou,
Yimin Yu,
William J. Israelsen,
M. Boxer,
S. Dimov,
Abhishek Jha,
Katherine R. Mattaini,
Christian M. Metallo,
B. Fiske,
Kevin D Courtney,
Scott Malstrom,
...
H. Veith,
Noel Southall,
W. Leister,
L. Dang,
Lewis C. Cantley,
Craig J Thomas,
R. D. Sentelle,
Wenhui Jiang,
S. Ponnusamy,
S. Gencer,
S. Selvam,
V. Ramshesh,
Yuri K Peterson,
J. Lemasters
|
10 |
2011 |
10
2011
|
Identification of RIP1 kinase as a specific cellular target of necrostatins.
14 auth.
A. Degterev,
J. Hitomi,
Megan Germscheid,
Irene L. Ch’en,
O. Korkina,
Xin-Chen Teng,
Derek W. Abbott,
G. Cuny,
C. Yuan*,
G. Wagner,
...
S. Hedrick,
S. Gerber,
A. Lugovskoy,
Junying Yuan
|
10 |
2008 |
10
2008
|
The role of iron and reactive oxygen species in cell death.
S. Dixon,
B. Stockwell
|
10 |
2014 |
10
2014
|
The role of dynamic conformational ensembles in biomolecular recognition.
David D. Boehr,
R. Nussinov,
P. Wright
|
10 |
2009 |
10
2009
|
The function of terpene natural products in the natural world.
J. Gershenzon,
N. Dudareva
|
10 |
2007 |
10
2007
|
Absolute Metabolite Concentrations and Implied Enzyme Active Site Occupancy in Escherichia coli
Bryson D. Bennett,
Elizabeth H Kimball,
Melissa Gao,
R. Osterhout,
S. Van Dien,
J. Rabinowitz
|
10 |
2009 |
10
2009
|
Mass spectrometry–based proteomics turns quantitative
Shao-En Ong,
M. Mann
|
10 |
2005 |
10
2005
|
Chemistry and biology of reactive oxygen species in signaling or stress responses.
B. Dickinson,
Christopher J. Chang
|
10 |
2011 |
10
2011
|
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
14 auth.
Baozhi Chen,
Michael E. Dodge,
Wei Tang,
Jianming Lu,
Zhiqiang Ma,
C. Fan,
Shuguang Wei,
Wayne Hao,
Jessica A. Kilgore,
N. Williams,
...
M. Roth,
J. Amatruda,
Chuo Chen,
L. Lum
|
10 |
2008 |
10
2008
|
Targeting virulence: a new paradigm for antimicrobial therapy
A. Clatworthy,
E. Pierson,
D. Hung
|
10 |
2007 |
10
2007
|
Mechanisms for copper acquisition, distribution and regulation.
Byung-Eun Kim,
Tracy Nevitt,
D. Thiele
|
10 |
2008 |
10
2008
|
