|
🐜
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N6-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO
29 auth.
Guifang Jia,
G. Zheng,
Chengqi Yi,
Tomas Lindahl,
D. Anastasiou,
Yimin Yu,
William J. Israelsen,
M. Boxer,
S. Dimov,
Abhishek Jha,
Katherine R. Mattaini,
Christian M. Metallo,
B. Fiske,
Kevin D Courtney,
Scott Malstrom,
...
H. Veith,
Noel Southall,
W. Leister,
L. Dang,
Lewis C. Cantley,
Craig J Thomas,
R. D. Sentelle,
Wenhui Jiang,
S. Ponnusamy,
S. Gencer,
S. Selvam,
V. Ramshesh,
Yuri K Peterson,
J. Lemasters
|
10 |
2011 |
10
🐜
|
|
🐜
|
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
43 auth.
D. Anastasiou,
Yimin Yu,
William J. Israelsen,
Jian-Kang Jiang,
M. Boxer,
B. Hong,
W. Tempel,
S. Dimov,
M. Shen,
Abhishek K. Jha,
Hua Yang,
Katherine R. Mattaini,
Christian M. Metallo,
B. Fiske,
K. Courtney,
...
S. Malstrom,
Tahsin M. Khan,
C. Kung,
A. P. Skoumbourdis,
H. Veith,
Noel Southall,
M. Walsh,
K. Brimacombe,
W. Leister,
Sophia Y. Lunt,
Zachary R. Johnson,
K. Yen,
K. Kunii,
S. Davidson,
H. Christofk,
C. Austin,
James Inglese,
M. H. Harris,
J. Asara,
G. Stephanopoulos,
F. Salituro,
Shengfang Jin,
L. Dang,
D. Auld,
Hee-won Park,
L. Cantley,
Craig J. Thomas,
M. V. Vander Heiden
|
9 |
2012 |
9
🐜
|
|
🦁
|
Comprehensive Characterization of Cytochrome P450 Isozyme Selectivity across Chemical Libraries
11 auth.
H. Veith,
Noel Southall,
Ruili Huang,
T. James,
D. Fayne,
N. Artemenko,
...
M. Shen,
James Inglese,
C. Austin,
D. Lloyd,
D. Auld
|
7 |
2009 |
7
🦁
|
|
🐜
|
Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.
14 auth.
M. Boxer,
Jian-Kang Jiang,
M. V. Vander Heiden,
M. Shen,
A. P. Skoumbourdis,
Noel Southall,
H. Veith,
W. Leister,
C. Austin,
H. Park,
...
James Inglese,
L. Cantley,
D. Auld,
Craig J. Thomas
|
7 |
2010 |
7
🐜
|
|
🐜
|
Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase.
14 auth.
Jian-Kang Jiang,
M. Boxer,
M. V. Vander Heiden,
M. Shen,
A. P. Skoumbourdis,
Noel Southall,
H. Veith,
W. Leister,
C. Austin,
H. Park,
...
James Inglese,
L. Cantley,
D. Auld,
Craig J. Thomas
|
6 |
2010 |
6
🐜
|
|
🐜
|
Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology.
8 auth.
Jennifer H Dao,
R. Kurzeja,
José M. Morachis,
H. Veith,
Jeffery K Lewis,
Violeta L Yu,
...
C. Tegley,
P. Tagari
|
5 |
2009 |
5
🐜
|
|
🐜
|
2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.
13 auth.
M. Walsh,
K. Brimacombe,
H. Veith,
James M. Bougie,
T. Daniel,
W. Leister,
L. Cantley,
William J. Israelsen,
M. V. Vander Heiden,
M. Shen,
...
D. Auld,
Craig J. Thomas,
M. Boxer
|
5 |
2011 |
5
🐜
|
|
🐬
|
Predictive Models for Cytochrome P450 Isozymes Based on Quantitative High Throughput Screening Data
Hongmao Sun,
H. Veith,
M. Xia,
C. Austin,
Ruili Huang
|
5 |
2011 |
5
🐬
|
|
🐜
|
HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration.
12 auth.
Heiko Büth,
B. Wolters,
Benedikt Hartwig,
Roland Meier-Bornheim,
H. Veith,
M. Hansen,
...
C. Sommerhoff,
N. Schaschke,
W. Machleidt,
N. Fusenig,
P. Boukamp,
K. Brix
|
5 |
2004 |
5
🐜
|
|
🐜
|
ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model
20 auth.
M. Walsh,
K. Brimacombe,
D. Anastasiou,
Yimin Yu,
William J. Israelsen,
B. Hong,
W. Tempel,
S. Dimov,
H. Veith,
Hua Yang,
...
C. Kung,
K. Yen,
L. Dang,
F. Salituro,
D. Auld,
Hee-won Park,
M. V. Heiden,
Craig J. Thomas,
M. Shen,
M. Boxer
|
5 |
2013 |
5
🐜
|
|
🐜
|
Discovery of novel hydroxy-thiazoles as HIF-alpha prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation.
14 auth.
C. Tegley,
V. Viswanadhan,
Kaustav Biswas,
M. Frohn,
Catherine Chang,
R. Bürli,
Jennifer H Dao,
H. Veith,
Norma Rogers,
S. Yoder,
...
G. Biddlecome,
P. Tagari,
Jennifer R. Allen,
R. Hungate
|
5 |
2008 |
5
🐜
|
