|
๐
|
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
64 auth.
Hui Gao,
Joshua M. Korn,
S. Ferretti,
John E Monahan,
Youzhen Wang,
Mallika Singh,
Chao Zhang,
C. Schnell,
Guizhi Yang,
Yun Zhang,
O Alejandro Balbin,
S. Barbe,
H. Cai,
F. Casey,
S. Chatterjee,
...
Derek Y Chiang,
S. Chuai,
Shawn Cogan,
Scott D Collins,
Ernesta Dammassa,
N. Ebel,
M. Embry,
J. Green,
A. Kauffmann,
C. Kowal,
Rebecca J Leary,
J. Lehรกr,
Ying Liang,
Alice T. Loo,
Edward G. Lorenzana,
E. Robert McDonald,
Margaret E McLaughlin,
J. Merkin,
R. Meyer,
Tara L Naylor,
M. Patawaran,
Anupama Reddy,
Claudia Rรถelli,
D. Ruddy,
Fernando Salangsang,
F. Santacroce,
Angad P Singh,
Yan Tang,
W. Tinetto,
Sonja Tobler,
Roberto Velazquez,
K. Venkatesan,
Fabian Von Arx,
Hui Qin Wang,
Zongyao Wang,
M. Wiesmann,
D. Wyss,
Fiona Xu,
H. Bitter,
P. Atadja,
E. Lees,
F. Hofmann,
E. Li,
N. Keen,
R. Cozens,
M. Jensen,
N. Pryer,
J. Williams,
W. Sellers
|
10 |
2015 |
10
๐
|
|
๐
|
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases
53 auth.
Ying-Nan P. Chen,
M. LaMarche,
H. Chan,
P. Fekkes,
J. Garciฬa-Fortanet,
M. Acker,
Brandon Antonakos,
C. Chen,
Zhouliang Chen,
V. Cooke,
J. Dobson,
Z. Deng,
F. Fei,
B. Firestone,
M. Fodor,
...
Cary Fridrich,
Hui Gao,
Denise Grunenfelder,
Huai-Xiang Hao,
Jaison Jacob,
Samuel Ho,
K. Hsiao,
Z. Kang,
R. Karki,
Mitsunori Kato,
J. Larrow,
L. Bonte,
Franรงois Lenoir,
Gang Liu,
Shumei Liu,
Dyuti Majumdar,
M. Meyer,
M. Palermo,
L. Perez,
Minying Pu,
E. Price,
C. Quinn,
S. Shakya,
M. Shultz,
J. Slisz,
K. Venkatesan,
Ping Wang,
M. Warmuth,
Sarah L. Williams,
Guizhi Yang,
Jing Yuan,
Ji-Hu Zhang,
P. Zhu,
T. Ramsey,
N. Keen,
W. Sellers,
T. Stams,
Pascal D. Fortin
|
9 |
2016 |
9
๐
|
|
๐
|
Single-vector inducible lentiviral RNAi system for oncology target validation
12 auth.
D. Wiederschain,
W. Susan,
Lin Chen,
Alice T. Loo,
Guizhi Yang,
A. Huang,
...
Yan Chen,
G. Caponigro,
Yung-mae M. Yao,
C. Lengauer,
W. Sellers,
J. D. Benson
|
8 |
2009 |
8
๐
|
|
๐
|
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5
44 auth.
Konstantinos J. Mavrakis,
E. McDonald,
M. Schlabach,
E. Billy,
G. Hoffman,
Antoine deWeck,
D. Ruddy,
K. Venkatesan,
Jianjun Yu,
Gregory McAllister,
M. Stump,
Rosalie S. deBeaumont,
Samuel Ho,
Yingzi Yue,
Yue Liu,
...
Y. Yan-Neale,
Guizhi Yang,
Fallon Lin,
H. Yin,
Hui Gao,
D. R. Kipp,
Songping Zhao,
J. T. McNamara,
E. Sprague,
B. Zheng,
Ying Lin,
Y. Cho,
J. Gu,
Kenneth Crawford,
D. Ciccone,
Alberto C. Vitari,
A. Lai,
V. Cรกpka,
Kristen E. Hurov,
J. A. Porter,
John A. Tallarico,
C. Mickanin,
E. Lees,
R. Pagliarini,
N. Keen,
Tobias Schmelzle,
F. Hofmann,
F. Stegmeier,
W. Sellers
|
8 |
2016 |
8
๐
|
|
๐
|
The metabolic function of cyclin D3โCDK6 kinase in cancer cell survival
21 auth.
Haizhen Wang,
Brandon N. Nicolay,
Joel M. Chick,
Xueliang Gao,
Y. Geng,
Hong Ren,
Hui Gao,
Guizhi Yang,
Juliet Williams,
Jan M. Suski,
...
M. Keibler,
E. Sicinska,
U. Gerdemann,
W. Haining,
W. Haining,
W. Haining,
Thomas M. Roberts,
K. Polyak,
S. Gygi,
Nicholas J. Dyson,
P. Sicinski
|
8 |
2017 |
8
๐
|
|
๐
|
Sphingosine kinase 1 promotes liver fibrosis by preventing miRโ19bโ3pโmediated inhibition of CCR2
11 auth.
T. Lan,
Changzheng Li,
Guizhi Yang,
Yue Sun,
Lihang Zhuang,
Yitao Ou,
...
Hui Li,
Genshu Wang,
T. Kisseleva,
D. Brenner,
Jiao Guo
|
6 |
2018 |
6
๐
|
|
๐
|
Cordycepin Ameliorates Nonalcoholic Steatohepatitis by Activation of the AMPโActivated Protein Kinase Signaling Pathway
16 auth.
T. Lan,
Yang Yu,
Jing Zhang,
Haonan Li,
Qiqing Weng,
Shuo Jiang,
S. Tian,
Tonghao Xu,
Shan Hu,
Guizhi Yang,
...
Yan Zhang,
Weixuan Wang,
Lexun Wang,
Qing Zhu,
X. Rong,
Jiao Guo
|
6 |
2021 |
6
๐
|
|
๐
|
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice
14 auth.
Jingjuan Hu,
Hai-hua Luo,
Jieyan Wang,
Wenli Tang,
Junqi Lu,
Shan Wu,
Zhi Xiong,
Guizhi Yang,
Zhenguo Chen,
T. Lan,
...
Hongwei Zhou,
Jing Nie,
Yong Jiang,
Peng Chen
|
6 |
2017 |
6
๐
|
|
๐
|
Andrographolide ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated renal oxidative stress and inflammation via Akt/NF-ฮบB pathway
13 auth.
Xiaoqian Ji,
Changzheng Li,
Yitao Ou,
Ning Li,
K. Yuan,
Guizhi Yang,
Xiaoyan Chen,
Zhicheng Yang,
Bing Liu,
W. Cheung,
...
Lijing Wang,
Ren-Xing Huang,
T. Lan
|
6 |
2016 |
6
๐
|
|
๐
|
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling
23 auth.
Chen Liu,
Hengyu Lu,
Hongyun Wang,
Alice T. Loo,
Xiamei Zhang,
Guizhi Yang,
C. Kowal,
S. Delach,
Ye Wang,
S. Goldoni,
...
W. Hastings,
Karrie K Wong,
Hui Gao,
M. Meyer,
S. Moody,
M. LaMarche,
J. Engelman,
J. Williams,
P. Hammerman,
T. Abrams,
Morvarid Mohseni,
G. Caponigro,
Huai-Xiang Hao
|
6 |
2020 |
6
๐
|
|
๐
|
Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction
21 auth.
Heather A. Huet,
J. Growney,
Jennifer A. Johnson,
Jing Li,
S. Bilic,
L. Ostrom,
M. Zafari,
C. Kowal,
Guizhi Yang,
Axelle Royo,
...
M. Jensen,
B. Dombrecht,
Kris Meerschaert,
J. Kolkman,
K. Cromie,
R. Mosher,
Hui Gao,
A. Schuller,
R. Isaacs,
W. Sellers,
S. Ettenberg
|
6 |
2014 |
6
๐
|
