🐜
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
196 auth.
P. Burton,
D. Clayton,
L. Cardon,
N. Craddock,
P. Deloukas,
A. Duncanson,
D. Kwiatkowski,
M. McCarthy,
W. Ouwehand,
N. Samani,
J. Todd,
P. Donnelly,
J. Barrett,
D. Davison,
D. Easton,
...
David Evans,
H. Leung,
J. Marchini,
A. Morris,
C. Spencer,
M. Tobin,
A. Attwood,
J. Boorman,
B. Cant,
Ursula Everson,
Judith M. Hussey,
J. Jolley,
A. S. Knight,
K. Koch,
Elizabeth Meech,
S. Nutland,
C. Prowse,
H. Stevens,
N. Taylor,
G. Walters,
N. Walker,
N. Watkins,
T. Winzer,
Richard W Jones,
W. McArdle,
S. Ring,
D. Strachan,
M. Pembrey,
G. Breen,
D. Clair,
S. Caesar,
K. Gordon-Smith,
L. Jones,
C. Fraser,
E. Green,
D. Grozeva,
M. Hamshere,
P. Holmans,
I. Jones,
G. Kirov,
V. Moskvina,
I. Nikolov,
M. O’Donovan,
M. Owen,
D. Collier,
A. Elkin,
A. Farmer,
R. Williamson,
P. McGuffin,
A. Young,
I. Ferrier,
S. Ball,
A. Balmforth,
J. Barrett,
D. Bishop,
M. Iles,
A. Maqbool,
N. Yuldasheva,
A. Hall,
P. Braund,
R. Dixon,
M. Mangino,
Suzanne E Stevens,
J. Thompson,
F. Bredin,
M. Tremelling,
M. Parkes,
H. Drummond,
C. Lees,
E. Nimmo,
J. Satsangi,
S. Fisher,
A. Forbes,
C. Lewis,
Clive M. Onnie,
N. Prescott,
J. Sanderson,
C. Mathew,
J. Barbour,
M. Mohiuddin,
C. Todhunter,
J. Mansfield,
T. Ahmad,
Fraser Cummings,
D. Jewell,
J. Webster,
Morris J. Brown,
G. Lathrop,
J. Connell,
A. Dominiczak,
C. Marcano,
B. Burke,
R. Dobson,
J. Gungadoo,
Kate L. Lee,
P. Munroe,
S. Newhouse,
Abiodun K Onipinla,
C. Wallace,
M. Xue,
M. Caulfield,
M. Farrall,
A. Barton,
I. Bruce,
Hannah Donovan,
S. Eyre,
Paul D. Gilbert,
S. Hider,
A. Hinks,
S. John,
C. Potter,
A. Silman,
D. Symmons,
W. Thomson,
Jane Worthington,
D. Dunger,
B. Widmer,
T. Frayling,
R. Freathy,
H. Lango,
J. Perry,
B. Shields,
M. Weedon,
A. Hattersley,
G. Hitman,
M. Walker,
K. Elliott,
C. Groves,
C. Lindgren,
N. W. Rayner,
N. Timpson,
E. Zeggini,
M. Newport,
G. Sirugo,
Emily J. Lyons,
F. Vannberg,
A. Hill,
L. Bradbury,
C. Farrar,
J. J. Pointon,
Paul Wordsworth,
M. Brown,
J. Franklyn,
J. Heward,
M. Simmonds,
S. Gough,
S. Seal,
M. Stratton,
N. Rahman,
M. Ban,
A. Goris,
S. Sawcer,
Alastair Compston,
D. Conway,
M. Jallow,
K. Rockett,
S. Bumpstead,
Amy Chaney,
K. Downes,
Mohammed J. R. Ghori,
R. Gwilliam,
S. Hunt,
M. Inouye,
A. Keniry,
E. King,
R. McGinnis,
Simon C. Potter,
R. Ravindrarajah,
P. Whittaker,
Claire Widden,
D. Withers,
Niall J. Cardin,
T. Ferreira,
Joanne Pereira-Gale,
Ingileif B. Hallgrímsdóttir,
Bryan N. Howie,
Z. Su,
Y. Teo,
Damjan Vukcevic,
D. Bentley,
A. Compston
|
13 |
2007 |
13 🐜
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🐜
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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
53 auth.
H. Ueda,
J. Howson,
L. Esposito,
J. Heward,
H. Snook,
Giselle Chamberlain,
Daniel B. Rainbow,
K. Hunter,
Annabel N. Smith,
G. Di Genova,
M. Herr,
I. Dahlman,
F. Payne,
D. Smyth,
C. Lowe,
...
R. Twells,
S. Howlett,
B. Healy,
S. Nutland,
H. Rance,
Vincent H. Everett,
L. Smink,
A. Lam,
H. Cordell,
N. Walker,
C. Bordin,
John S Hulme,
C. Motzo,
F. Cucca,
J. Hess,
M. Metzker,
J. Rogers,
S. Gregory,
A. Allahabadia,
R. Nithiyananthan,
E. Tuomilehto-Wolf,
J. Tuomilehto,
P. Bingley,
K. Gillespie,
D. Undlien,
K. Rønningen,
C. Guja,
C. Ionescu-Tîrgoviste,
D. Savage,
A. Maxwell,
D. Carson,
C. Patterson,
J. Franklyn,
D. Clayton,
L. Peterson,
L. Wicker,
J. Todd,
S. Gough
|
11 |
2003 |
11 🐜
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🐜
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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
40 auth.
J. Todd,
N. Walker,
J. Cooper,
D. Smyth,
K. Downes,
V. Plagnol,
R. A. Bailey,
S. Nejentsev,
Sarah F. Field,
F. Payne,
C. Lowe,
Jeffrey S. Szeszko,
J. Hafler,
L. Zeitels,
Jennie H. M. Yang,
...
A. Vella,
S. Nutland,
H. Stevens,
Helen Schuilenburg,
Gillian Coleman,
M. Maisuria,
William Meadows,
L. Smink,
B. Healy,
O. Burren,
A. Lam,
Nigel R. Ovington,
James Allen,
E. Adlem,
H. Leung,
C. Wallace,
J. Howson,
C. Guja,
C. Ionescu-Tîrgoviste,
M. Simmonds,
J. Heward,
S. Gough,
D. Dunger,
L. Wicker,
D. Clayton
|
10 |
2007 |
10 🐜
|
🐜
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Genome-wide association study and meta-analysis finds over 40 loci affect risk of type 1 diabetes
18 auth.
J. Barrett,
David G. Clayton,
Patrick Concannon,
B. Akolkar,
Jason D Cooper,
Henry A Erlich,
Cécile Julier,
Grant Morahan,
Jørn Nerup,
Concepcion Nierras,
...
Vincent Plagnol,
F. Pociot,
Helen Schuilenburg,
D. Smyth,
H. Stevens,
John A. Todd,
N. Walker,
Stephen S Rich
|
10 |
2009 |
10 🐜
|
🐬
|
Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
S. Nejentsev,
N. Walker,
D. Riches,
M. Egholm,
J. Todd
|
9 |
2009 |
9 🐬
|
🐜
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Shared and distinct genetic variants in type 1 diabetes and celiac disease.
16 auth.
D. Smyth,
V. Plagnol,
N. Walker,
J. Cooper,
K. Downes,
Jennie H. M. Yang,
J. Howson,
H. Stevens,
R. McManus,
C. Wijmenga,
...
Graham A. R. Heap,
P. Dubois,
D. Clayton,
K. Hunt,
D. V. van Heel,
J. Todd
|
9 |
2008 |
9 🐜
|
🐜
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A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
14 auth.
D. Smyth,
J. Cooper,
Rebecca Bailey,
Sarah F. Field,
O. Burren,
L. Smink,
C. Guja,
C. Ionescu-Tîrgoviste,
B. Widmer,
D. Dunger,
...
D. Savage,
N. Walker,
D. Clayton,
J. Todd
|
9 |
2006 |
9 🐜
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🐜
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Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
26 auth.
S. Onengut-Gumuscu,
Wei-Min Chen,
O. Burren,
N. Cooper,
A. Quinlan,
J. Mychaleckyj,
Emily Farber,
J. Bonnie,
M. Szpak,
E. Schofield,
P. Achuthan,
Hui Guo,
Mary D. Fortune,
H. Stevens,
N. Walker,
...
L. D. Ward,
A. Kundaje,
Manolis Kellis,
M. Daly,
J. Barrett,
J. Cooper,
P. Deloukas,
J. Todd,
C. Wallace,
P. Concannon,
S. Rich
|
9 |
2015 |
9 🐜
|
🐜
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Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
210 auth.
S. Nejentsev,
J. Howson,
N. Walker,
Jeffrey S. Szeszko,
Sarah F. Field,
H. Stevens,
Pamela Reynolds,
Matthew Hardy,
Erna King,
J. Masters,
John S Hulme,
L. Maier,
D. Smyth,
Rebecca Bailey,
J. Cooper,
...
G. Ribas,
R. Campbell,
D. Clayton,
J. Todd,
Paul R. Burton,
L. Cardon,
N. Craddock,
P. Deloukas,
A. Duncanson,
D. Kwiatkowski,
M. McCarthy,
W. Ouwehand,
N. Samani,
P. Donnelly,
J. Barrett,
D. Davison,
D. Easton,
David Evans,
H. Leung,
J. Marchini,
Andrew P Morris,
C. Spencer,
M. Tobin,
A. Attwood,
J. Boorman,
B. Cant,
Ursula Everson,
Judith M. Hussey,
J. Jolley,
A. S. Knight,
K. Koch,
Elizabeth Meech,
S. Nutland,
C. Prowse,
N. Taylor,
G. Walters,
N. Watkins,
T. Winzer,
Richard Jones,
W. McArdle,
S. Ring,
D. Strachan,
M. Pembrey,
G. Breen,
D. Clair,
S. Caesar,
K. Gordon-Smith,
L. Jones,
C. Fraser,
E. Green,
D. Grozeva,
M. Hamshere,
P. Holmans,
I. Jones,
G. Kirov,
V. Moskvina,
I. Nikolov,
M. O’Donovan,
M. Owen,
D. A. Collier,
A. Elkin,
A. Farmer,
R. Williamson,
P. McGuffin,
A. H. Young,
I. Ferrier,
S. Ball,
A. Balmforth,
J. Barrett,
D. Bishop,
M. Iles,
A. Maqbool,
N. Yuldasheva,
A. Hall,
P. Braund,
R. Dixon,
M. Mangino,
Suzanne E Stevens,
J. Thompson,
F. Bredin,
M. Tremelling,
M. Parkes,
H. Drummond,
C. Lees,
E. Nimmo,
J. Satsangi,
S. Fisher,
A. Forbes,
C. Lewis,
Clive M. Onnie,
N. Prescott,
J. Sanderson,
C. Mathew,
J. Barbour,
M. Mohiuddin,
Catherine E. Todhunter,
J. Mansfield,
Fraser Cummings,
D. Jewell,
J. Webster,
Morris J. Brown,
G. Lathrop,
J. Connell,
A. Dominiczak,
C. Braga,
B. Burke,
Richard J. B. Dobson,
J. Gungadoo,
Kate L. Lee,
P. Munroe,
S. Newhouse,
Abiodun K Onipinla,
C. Wallace,
M. Xue,
M. Caulfield,
M. Farrall,
A. Barton,
I. Bruce,
Hannah Donovan,
S. Eyre,
Paul D. Gilbert,
S. Hider,
A. Hinks,
S. John,
C. Potter,
A. Silman,
D. Symmons,
W. Thomson,
Jane Worthington,
D. B. Dunger,
B. Widmer,
T. Frayling,
R. Freathy,
H. Lango,
J. Perry,
B. Shields,
M. Weedon,
A. Hattersley,
G. Hitman,
Mark Walker,
K. Elliott,
C. Groves,
C. Lindgren,
N. W. Rayner,
N. Timpson,
E. Zeggini,
M. Newport,
G. Sirugo,
Emily J. Lyons,
F. Vannberg,
A. Hill,
L. Bradbury,
C. Farrar,
Jennifer J. Pointon,
P. Wordsworth,
Matthew A. Brown,
J. Franklyn,
J. Heward,
M. Simmonds,
S. Gough,
S. Seal,
Michael R. Stratton,
Nazneen Rahman,
M. Ban,
A. Goris,
S. Sawcer,
Alastair Compston,
D. Conway,
M. Jallow,
K. Rockett,
C. Bryan,
S. Bumpstead,
Amy Chaney,
K. Downes,
J. Ghori,
R. Gwilliam,
S. Hunt,
M. Inouye,
A. Keniry,
Emma King,
R. McGinnis,
Simon C. Potter,
R. Ravindrarajah,
P. Whittaker,
D. Withers,
Niall J. Cardin,
T. Ferreira,
Joanne Pereira-Gale,
Ingeleif B. Hallgrimsdottir,
Bryan N. Howie,
Z. Su,
Y. Teo,
Damjan Vukcevic,
D. Bentley,
A. Compston
|
9 |
2007 |
9 🐜
|
🐜
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Population structure, differential bias and genomic control in a large-scale, case-control association study
19 auth.
D. Clayton,
N. Walker,
D. Smyth,
Rebecca Pask,
J. Cooper,
L. Maier,
L. Smink,
A. Lam,
Nigel R. Ovington,
H. Stevens,
...
S. Nutland,
J. Howson,
M. Faham,
M. Moorhead,
H. Jones,
M. Falkowski,
P. Hardenbol,
T. Willis,
J. Todd
|
9 |
2005 |
9 🐜
|
🐜
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Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.
23 auth.
D. Smyth,
J. Cooper,
J. Collins,
J. Heward,
J. Franklyn,
J. Howson,
A. Vella,
S. Nutland,
H. Rance,
L. Maier,
...
B. J. Barratt,
C. Guja,
C. Ionescu-Tîrgoviste,
D. Savage,
D. Dunger,
B. Widmer,
D. Strachan,
S. Ring,
N. Walker,
D. Clayton,
R. Twells,
S. Gough,
J. Todd
|
9 |
2004 |
9 🐜
|
🐜
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Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls
217 auth.
N. Craddock,
M. Hurles,
Niall J. Cardin,
R. Pearson,
V. Plagnol,
S. Robson,
Damjan Vukcevic,
Chris P. Barnes,
D. Conrad,
E. Giannoulatou,
Chris Holmes,
J. Marchini,
K. Stirrups,
M. Tobin,
L. Wain,
...
C. Yau,
J. Aerts,
T. Ahmad,
T. Andrews,
Hazel Arbury,
A. Attwood,
A. Auton,
S. Ball,
A. Balmforth,
J. Barrett,
I. Barroso,
A. Barton,
A. Bennett,
Seema Bhaskar,
K. Błaszczyk,
J. Bowes,
O. Brand,
P. Braund,
F. Bredin,
G. Breen,
M. Brown,
I. Bruce,
J. Bull,
O. Burren,
J. Burton,
Jake K. Byrnes,
S. Caesar,
C. Clee,
A. Coffey,
J. Connell,
J. D. Cooper,
A. Dominiczak,
K. Downes,
H. Drummond,
D. Dudakia,
A. Dunham,
Bernadette Ebbs,
D. Eccles,
S. Edkins,
C. Edwards,
Anna Elliot,
P. Emery,
David Evans,
G. Evans,
S. Eyre,
A. Farmer,
I. Ferrier,
L. Feuk,
Tomas W. Fitzgerald,
E. Flynn,
A. Forbes,
L. Forty,
J. Franklyn,
R. Freathy,
P. Gibbs,
Paul D. Gilbert,
O. Gokumen,
K. Gordon-Smith,
Elizabeth E Gray,
E. Green,
C. Groves,
D. Grozeva,
R. Gwilliam,
A. Hall,
Naomi Hammond,
Matthew Hardy,
Pille Harrison,
N. Hassanali,
H. Hebaishi,
Sarah Hines,
A. Hinks,
G. Hitman,
L. Hocking,
E. Howard,
Philip N. Howard,
J. Howson,
D. Hughes,
S. Hunt,
J. Isaacs,
Mahim Jain,
D. Jewell,
T. Johnson,
J. Jolley,
I. Jones,
L. Jones,
G. Kirov,
C. Langford,
H. Lango-Allen,
G. Lathrop,
James C. Lee,
Kate L. Lee,
C. Lees,
Lewis Kf,
C. Lindgren,
Meeta Maisuria-Armer,
J. Maller,
J. Mansfield,
Paul Martin,
D. Massey,
W. McArdle,
P. McGuffin,
K. McLay,
A. Mentzer,
M. Mimmack,
A. Morgan,
A. Morris,
C. Mowat,
S. Myers,
W. Newman,
E. Nimmo,
M. O’Donovan,
Abiodun K Onipinla,
Ifejinelo Onyiah,
Nigel R. Ovington,
M. Owen,
Kimmo Palin,
K. Parnell,
D. Pernet,
J. Perry,
A. Phillips,
D. Pinto,
N. Prescott,
I. Prokopenko,
M. Quail,
S. Rafelt,
N. W. Rayner,
R. Redon,
D. Reid,
A. Renwick,
S. Ring,
N. Robertson,
E. Russell,
D. Clair,
J. Sambrook,
J. Sanderson,
Helen Schuilenburg,
C. Scott,
R. Scott,
S. Seal,
S. Shaw-Hawkins,
B. Shields,
M. Simmonds,
D. Smyth,
Elilan Somaskantharajah,
Katarina Spanova,
S. Steer,
J. Stephens,
H. Stevens,
M. Stone,
Z. Su,
D. Symmons,
J. Thompson,
W. Thomson,
M. Travers,
C. Turnbull,
A. Valsesia,
M. Walker,
N. Walker,
C. Wallace,
M. Warren-Perry,
N. Watkins,
J. Webster,
M. Weedon,
A. Wilson,
Matt Woodburn,
B. P. Wordsworth,
A. Young,
E. Zeggini,
N. Carter,
T. Frayling,
Charles Lee,
G. McVean,
P. Munroe,
A. Palotie,
S. Sawcer,
S. Scherer,
D. Strachan,
C. Tyler-Smith,
M. Brown,
P. Burton,
M. Caulfield,
A. Compston,
M. Farrall,
S. Gough,
A. Hall,
A. Hattersley,
A. Hill,
C. Mathew,
M. Pembrey,
J. Satsangi,
M. Stratton,
Jane Worthington,
P. Deloukas,
A. Duncanson,
D. Kwiatkowski,
M. McCarthy,
W. Ouwehand,
M. Parkes,
N. Rahman,
J. Todd,
N. Samani,
P. Donnelly
|
9 |
2010 |
9 🐜
|
🐜
|
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
12 auth.
J. Cooper,
D. Smyth,
A. Smiles,
V. Plagnol,
N. Walker,
James Allen,
...
K. Downes,
J. Barrett,
B. Healy,
J. Mychaleckyj,
J. Warram,
J. Todd
|
9 |
2008 |
9 🐜
|
🐜
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Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
13 auth.
C. Lowe,
J. Cooper,
T. Brusko,
N. Walker,
D. Smyth,
Rebecca Bailey,
Kirsi Bourget,
V. Plagnol,
Sarah F. Field,
M. Atkinson,
...
D. Clayton,
L. Wicker,
J. Todd
|
8 |
2007 |
8 🐜
|