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🐜
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Catalytic in vivo protein knockdown by small-molecule PROTACs.
29 auth.
Daniel P. Bondeson,
A. Mareş,
I. E. Smith,
Eunhwa Ko,
Sebastien Campos,
Afjal H Miah,
K. Mulholland,
Natasha Routly,
Dennis L. Buckley,
J. Gustafson,
N. Zinn,
P. Grandi,
S. Shimamura,
G. Bergamini,
Maria Faelth-Savitski,
...
M. Bantscheff,
Carly S Cox,
D. Gordon,
Ryan R Willard,
J. Flanagan,
Linda N. Casillas,
B. Votta,
W. den Besten,
K. Famm,
L. Kruidenier,
P. Carter,
J. Harling,
I. Churcher,
C. Crews
|
9 |
2015 |
9
🐜
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|
🦁
|
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
31 auth.
L. Kruidenier,
C. Chung,
Zhongjun Cheng,
J. Liddle,
K. Che,
G. Joberty,
M. Bantscheff,
C. Bountra,
A. Bridges,
Hawa Diallo,
D. Eberhard,
Sue E. Hutchinson,
E. Jones,
R. Katso,
Melanie V. Leveridge,
...
P. Mander,
J. Mosley,
César Ramírez‐Molina,
P. Rowland,
C. Schofield,
R. Sheppard,
Julia E. Smith,
C. Swales,
R. Tanner,
P. Thomas,
A. Tumber,
G. Drewes,
U. Oppermann,
D. Patel,
Kevin Lee,
D. Wilson
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9 |
2012 |
9
🦁
|
|
🦁
|
Oxidative stress as a pathogenic factor in inflammatory bowel disease — radicals or ridiculous?
L. Kruidenier,
H. Verspaget
|
8 |
2002 |
8
🦁
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|
🦁
|
Intestinal oxidative damage in inflammatory bowel disease: semi‐quantification, localization, and association with mucosal antioxidants
L. Kruidenier,
I. Kuiper,
C. Lamers,
H. Verspaget
|
8 |
2003 |
8
🦁
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|
🐜
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Contrasting roles for histone 3 lysine 27 demethylases in acute lymphoblastic leukemia
26 auth.
P. Ntziachristos,
A. Tsirigos,
G. Welstead,
Thomas Trimarchi,
Sofia Bakogianni,
Luyao Xu,
Evangelia Loizou,
Linda Holmfeldt,
Alexandros Strikoudis,
B. King,
Jasper Mullanders,
J. Becksfort,
Jelena Nedjic,
E. Paietta,
M. Tallman,
...
J. Rowe,
G. Tonon,
T. Satoh,
L. Kruidenier,
R. Prinjha,
S. Akira,
P. Van Vlierberghe,
A. Ferrando,
R. Jaenisch,
C. Mullighan,
I. Aifantis
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8 |
2014 |
8
🐜
|
|
🐜
|
Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group.
29 auth.
M. Lobera,
K. Madauss,
D. T. Pohlhaus,
Q. Wright,
M. Trocha,
Darby R Schmidt,
E. Baloglu,
R. Trump,
M. Head,
G. Hofmann,
Monique F Murray-Thompson,
B. Schwartz,
S. Chakravorty,
Zining Wu,
P. Mander,
...
L. Kruidenier,
R. A. Reid,
W. Burkhart,
B. Turunen,
J. Rong,
C. Wagner,
M. Moyer,
C. Wells,
X. Hong,
John T. Moore,
Jon D. Williams,
D. Soler,
S. Ghosh,
M. A. Nolan
|
8 |
2013 |
8
🐜
|
|
🐬
|
Assessment of the risk of infection by Cryptosporidium or Giardia in drinking water from a surface water source
P. Teunis,
G. Medema,
L. Kruidenier,
A. Havelaar
|
7 |
1997 |
7
🐬
|
|
🦁
|
Imbalanced secondary mucosal antioxidant response in inflammatory bowel disease
7 auth.
L. Kruidenier,
I. Kuiper,
W. van Duijn,
M. Mieremet-Ooms,
R. V. van Hogezand,
C. Lamers,
...
H. Verspaget
|
7 |
2003 |
7
🦁
|
|
🐜
|
Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases.
10 auth.
Qiang Gao,
M. Meijer,
F. Kubben,
C. Sier,
L. Kruidenier,
W. V. Duijn,
...
M. V. D. Berg,
R. A. Hogezand,
C. Lamers,
H. Verspaget
|
7 |
2005 |
7
🐜
|
|
🦁
|
Differential mucosal expression of three superoxide dismutase isoforms in inflammatory bowel disease
7 auth.
L. Kruidenier,
I. Kuiper,
W. van Duijn,
S. Marklund,
R. V. van Hogezand,
C. Lamers,
...
H. Verspaget
|
6 |
2003 |
6
🦁
|
|
🐢
|
Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease
18 auth.
A. Di Sabatino,
L. Rovedatti,
R. Kaur,
J. Spencer,
Jon T. Brown,
V. Morisset,
P. Biancheri,
N. Leakey,
J. Wilde,
Laurie Scott,
...
G. Corazza,
Kevin Lee,
Neel Sengupta,
C. Knowles,
M. Gunthorpe,
P. Mclean,
T. Macdonald,
L. Kruidenier
|
6 |
2009 |
6
🐢
|
|
🐜
|
The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival.
16 auth.
T. Burgold,
N. Voituron,
Marieta Caganova,
P. Tripathi,
C. Menuet,
B. Tusi,
F. Spreafico,
M. Bévengut,
C. Gestreau,
S. Buontempo,
...
A. Simeone,
L. Kruidenier,
G. Natoli,
S. Casola,
G. Hilaire,
G. Testa
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6 |
2012 |
6
🐜
|
