|
π
|
Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells.
10 auth.
G. James,
J. Goldstein,
Michael S. Brown,
T. Rawson,
T. Somers,
R. McDowell,
...
C. Crowley,
Brian K. Lucas,
A. Levinson,
J. Marsters
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9 |
1993 |
9
π
|
|
π
|
From Peptide to Non-Peptide. 2. The de Novo Design of Potent, Non-peptidal Inhibitors of Platelet Aggregation Based on a Benzodiazepinedione Scaffold
9 auth.
R. McDowell,
B. Blackburn,
T. Gadek,
L. McGee,
T. Rawson,
M. Reynolds,
...
K. Robarge,
T. Somers,
E. Thorsett
|
6 |
1994 |
6
π
|
|
π
|
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
21 auth.
Ignacio Aliagas-Martin,
D. Burdick,
L. Corson,
Jennafer Dotson,
Jason Drummond,
Carter T. Fields,
Oscar W. Huang,
Thomas L. Hunsaker,
Tracy Kleinheinz,
Elaine B Krueger,
...
Jun Liang,
John G. Moffat,
G. Phillips,
R. Pulk,
T. Rawson,
M. Ultsch,
L. Walker,
C. Wiesmann,
Birong Zhang,
B. Zhu,
A. Cochran
|
6 |
2009 |
6
π
|
|
π
|
Discovery of potent and selective pyrazolopyrimidine janus kinase 2 inhibitors.
23 auth.
Emily J. Hanan,
Anne van Abbema,
K. Barrett,
W. Blair,
J. Blaney,
Christine Chang,
C. Eigenbrot,
S. Flynn,
Paul Gibbons,
Christopher A. Hurley,
...
J. Kenny,
J. Kulagowski,
Leslie B. Lee,
Steven Magnuson,
C. Morris,
J. Murray,
Richard M Pastor,
T. Rawson,
Michael Siu,
M. Ultsch,
Aihe Zhou,
D. Sampath,
J. Lyssikatos
|
6 |
2012 |
6
π
|
|
π
|
Potent Ξ±4Ξ²1 Peptide Antagonists as Potential Anti-Inflammatory Agents
17 auth.
D. Y. Jackson,
C. Quan,
D. Artis,
T. Rawson,
B. Blackburn,
M. Struble,
G. Fitzgerald,
K. Chan,
S. Mullins,
J. Burnier,
...
W. Fairbrother,
K. Clark,
M. Berisini,
H. Chui,
M. Renz,
Susan Jones,
S. Fong
|
6 |
1997 |
6
π
|
|
π¦
|
A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability.
30 auth.
T. Rawson,
M. RΓΌth,
E. Blackwood,
D. Burdick,
L. Corson,
Jennafer Dotson,
Jason Drummond,
Carter T. Fields,
G. Georges,
B. Goller,
J. Halladay,
Thomas L. Hunsaker,
Tracy Kleinheinz,
H. Krell,
Jun Li,
...
Jun Liang,
A. Limberg,
Angela McNutt,
John G. Moffat,
G. Phillips,
Y. Ran,
B. Safina,
M. Ultsch,
L. Walker,
C. Wiesmann,
Birong Zhang,
Aihe Zhou,
B. Zhu,
P. RΓΌger,
A. Cochran
|
5 |
2008 |
5
π¦
|
|
π
|
Benzodiazepine peptidomimetic inhibitors of farnesyltransferase.
10 auth.
J. Marsters,
R. McDowell,
M. Reynolds,
D. Oare,
T. Somers,
M. Stanley,
...
T. Rawson,
M. Struble,
D. Burdick,
K. Chan
|
5 |
1994 |
5
π
|
|
π
|
A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo*
19 auth.
A. Olivero,
C. Eigenbrot,
R. Goldsmith,
K. Robarge,
D. Artis,
J. Flygare,
T. Rawson,
D. Sutherlin,
S. Kadkhodayan,
M. Beresini,
...
L. Elliott,
G. DeGuzman,
D. Banner,
M. Ultsch,
U. Marzec,
S. Hanson,
C. Refino,
S. Bunting,
D. Kirchhofer
|
5 |
2005 |
5
π
|
|
π
|
Potent alpha 4 beta 1 peptide antagonists as potential anti-inflammatory agents.
17 auth.
D. Y. Jackson,
C. Quan,
D. Artis,
T. Rawson,
B. Blackburn,
M. Struble,
G. Fitzgerald,
K. Chan,
S. Mullins,
J. Burnier,
...
W. Fairbrother,
K. Clark,
M. Berisini,
H. Chui,
M. Renz,
S. Jones,
S. Fong
|
4 |
1997 |
4
π
|
|
π¦
|
Separation of 21-(R)- and 21-(S)-argatroban: solubility and activity of the individual diastereoisomers.
T. Rawson,
K. VanGorp,
J. Yang,
T. Kogan
|
3 |
1993 |
3
π¦
|
