|
🐜
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A recurrent mutation in PALB2 in Finnish cancer families
28 auth.
H. Erkko,
B. Xia,
J. Nikkilä,
J. Schleutker,
K. Syrjäkoski,
A. Mannermaa,
A. Kallioniemi,
K. Pylkäs,
S. Karppinen,
K. Rapakko,
A. Miron,
Qing Sheng,
Guilan Li,
Henna Mattila,
D. Bell,
...
D. Haber,
Mervi Grip,
M. Reiman,
A. Jukkola-Vuorinen,
A. Mustonen,
J. Kere,
L. Aaltonen,
V. Kosma,
V. Kataja,
Y. Soini,
R. Drapkin,
D. Livingston,
R. Winqvist
|
8 |
2007 |
8
🐜
|
|
🐜
|
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity
25 auth.
Jacqueline H. L. Fok,
A. Ramos-Montoya,
M. Vázquez-Chantada,
P. Wijnhoven,
Valeria Follia,
N. James,
Paul M. Farrington,
Ankur Karmokar,
Sophie E. Willis,
Jonathan Cairns,
J. Nikkilä,
D. Beattie,
Gillian M. Lamont,
M. Finlay,
Joanne Wilson,
...
Aaron Smith,
L. O’Connor,
S. Ling,
S. Fawell,
M. J. O’Connor,
S. Hollingsworth,
E. Dean,
Frederick W. Goldberg,
B. Davies,
E. Cadogan
|
7 |
2019 |
7
🐜
|
|
🐜
|
Penetrance Analysis of the PALB2 c.1592delT Founder Mutation
16 auth.
H. Erkko,
J. Dowty,
J. Nikkilä,
K. Syrjäkoski,
A. Mannermaa,
K. Pylkäs,
M. Southey,
K. Holli,
A. Kallioniemi,
A. Jukkola-Vuorinen,
...
V. Kataja,
V. Kosma,
B. Xia,
D. Livingston,
R. Winqvist,
J. Hopper
|
7 |
2008 |
7
🐜
|
|
🦁
|
Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells
15 auth.
J. Nikkilä,
Rahul Kumar,
James Campbell,
I. Brandsma,
H. Pemberton,
Fredrik Wållberg,
Kinga Nagy,
I. Scheer,
B. Vértessy,
A. Serebrenik,
...
V. Monni,
R. Harris,
S. Pettitt,
A. Ashworth,
C. Lord
|
6 |
2017 |
6
🦁
|
|
🐜
|
BRD4 facilitates replication stress-induced DNA damage response
12 auth.
Jingwen Zhang,
A. Dulak,
M. Hattersley,
Brandon S. Willis,
J. Nikkilä,
A. Wang,
...
A. Lau,
C. Reimer,
M. Zinda,
S. Fawell,
G. Mills,
Huawei Chen
|
6 |
2018 |
6
🐜
|
|
🦁
|
Heterozygous mutations in PALB2 cause DNA replication and damage response defects
11 auth.
J. Nikkilä,
Ann Christin Parplys,
K. Pylkäs,
M. Bose,
Yanying Huo,
K. Borgmann,
...
K. Rapakko,
P. Nieminen,
B. Xia,
H. Pospiech,
R. Winqvist
|
6 |
2013 |
6
🦁
|
|
🦁
|
Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function
10 auth.
J. Nikkilä,
K. Coleman,
D. Morrissey,
K. Pylkäs,
H. Erkko,
T. Messick,
...
S. Karppinen,
A. Amelina,
R. Winqvist,
R. Greenberg
|
6 |
2009 |
6
🦁
|
|
🐜
|
Breast Cancer–Associated Abraxas Mutation Disrupts Nuclear Localization and DNA Damage Response Functions
12 auth.
Szilvia Solyom,
Bernadette Aressy,
K. Pylkäs,
Jeffrey Patterson-Fortin,
Jaana M. Hartikainen,
A. Kallioniemi,
...
S. Kauppila,
J. Nikkilä,
V. Kosma,
A. Mannermaa,
R. Greenberg,
R. Winqvist
|
5 |
2012 |
5
🐜
|
|
🐜
|
Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.
9 auth.
P. Rantakari,
J. Nikkilä,
Heli Jokela,
Roxana Ola,
K. Pylkäs,
Heidi Lagerbohm,
...
K. Sainio,
M. Poutanen,
R. Winqvist
|
5 |
2010 |
5
🐜
|
|
🐬
|
Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families
K. Pylkäs,
H. Erkko,
J. Nikkilä,
Szilvia Solyom,
R. Winqvist
|
5 |
2008 |
5
🐬
|
