|
🐜
|
POT1 loss-of-function variants predispose to familial melanoma
30 auth.
C. D. Robles-Espinoza,
M. Harland,
A. Ramsay,
L. Aoude,
V. Quesada,
Zhihao Ding,
K. Pooley,
Antonia L. Pritchard,
Jessamy Tiffen,
M. Petljak,
Jane M Palmer,
J. Symmons,
P. Johansson,
M. Stark,
Michael Gartside,
...
H. Snowden,
Grant W. Montgomery,
N. G. Martin,
Jimmy Z. Liu,
Jiyeon Choi,
M. Makowski,
K. Brown,
A. Dunning,
Thomas M. Keane,
C. López-Otín,
N. Gruis,
Nicholas K Hayward,
D. T. Bishop,
J. Newton-Bishop,
David J. Adams
|
8 |
2014 |
8
🐜
|
|
🦁
|
Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis
35 auth.
M. Petljak,
L. Alexandrov,
Jonathan S Brammeld,
S. Price,
D. Wedge,
Sebastian Grossmann,
K. Dawson,
Y. Ju,
F. Iorio,
J. Tubío,
C. Koh,
Ilias Georgakopoulos-Soares,
Bernardo Rodriguez-Martin,
Burçak Otlu,
S. O’Meara,
...
A. Butler,
A. Menzies,
S. Bhosle,
K. Raine,
David Jones,
J. Teague,
Kathryn M Beal,
Calli Latimer,
L. O’Neill,
Jorge Zamora,
Elizabeth Anderson,
Nikita Patel,
M. Maddison,
B. Ng,
Jennifer Graham,
M. Garnett,
U. McDermott,
S. Nik-Zainal,
P. Campbell,
M. Stratton
|
8 |
2019 |
8
🦁
|
|
🐜
|
Genome sequencing of normal cells reveals developmental lineages and mutational processes
23 auth.
S. Behjati,
Meritxell Huch,
R. Boxtel,
W. Karthaus,
D. Wedge,
Asif U. Tamuri,
I. Martincorena,
M. Petljak,
L. Alexandrov,
G. Gundem,
...
P. Tarpey,
Sophie F. Roerink,
J. Blokker,
M. Maddison,
L. Mudie,
B. Robinson,
S. Nik-Zainal,
P. Campbell,
N. Goldman,
M. Wetering,
E. Cuppen,
H. Clevers,
M. Stratton
|
8 |
2014 |
8
🐜
|
|
🐜
|
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer
17 auth.
S. Nik-Zainal,
D. Wedge,
L. Alexandrov,
M. Petljak,
A. Butler,
N. Bolli,
Helen R Davies,
S. Knappskog,
Sancha Martin,
E. Papaemmanuil,
...
Manasa Ramakrishna,
A. Shlien,
I. Simonic,
Yali Xue,
C. Tyler-Smith,
P. Campbell,
M. Stratton
|
8 |
2014 |
8
🐜
|
|
🐜
|
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
41 auth.
Y. Ju,
I. Martincorena,
M. Gerstung,
M. Petljak,
L. Alexandrov,
R. Rahbari,
D. Wedge,
Helen R Davies,
Manasa Ramakrishna,
A. Fullam,
Sancha Martin,
Christopher Alder,
Nikita Patel,
Stephen J. Gamble,
S. O’Meara,
...
D. Giri,
Torril Sauer,
S. Pinder,
C. Purdie,
Å. Borg,
H. Stunnenberg,
M. J. van de Vijver,
B. Tan,
C. Caldas,
A. Tutt,
N. Ueno,
L. V. van’t Veer,
J. Martens,
C. Sotiriou,
S. Knappskog,
P. Span,
S. Lakhani,
J. Eyfjörd,
A. Børresen-Dale,
A. Richardson,
A. Thompson,
A. Viari,
M. Hurles,
S. Nik-Zainal,
P. Campbell,
M. Stratton
|
7 |
2017 |
7
🐜
|
|
🦁
|
Mechanisms of APOBEC3 mutagenesis in human cancer cells
12 auth.
M. Petljak,
Alexandra Dananberg,
Kevan Chu,
E. Bergstrom,
Josefine Striepen,
P. von Morgen,
...
Yanyang Chen,
H. Shah,
J. Sale,
L. Alexandrov,
M. Stratton,
J. Maciejowski
|
6 |
2022 |
6
🦁
|
|
🐜
|
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
13 auth.
E. Bergstrom,
J. Luebeck,
M. Petljak,
Azhar Khandekar,
M. Barnes,
Tongwu Zhang,
C. Steele,
N. Pillay,
M. Landi,
V. Bafna,
...
P. Mischel,
R. Harris,
L. Alexandrov
|
6 |
2022 |
6
🐜
|
|
🦁
|
Understanding mutagenesis through delineation of mutational signatures in human cancer.
M. Petljak,
L. Alexandrov
|
6 |
2016 |
6
🦁
|
|
🦁
|
Molecular origins of APOBEC-associated mutations in cancer.
M. Petljak,
J. Maciejowski
|
5 |
2020 |
5
🦁
|
|
🐜
|
Germline TERT promoter mutations are rare in familial melanoma
16 auth.
M. Harland,
M. Petljak,
C. D. Robles-Espinoza,
Zhihao Ding,
N. Gruis,
R. van Doorn,
K. Pooley,
A. Dunning,
L. Aoude,
K. Wadt,
...
A. Gerdes,
K. Brown,
Nicholas K Hayward,
J. Newton-Bishop,
David J. Adams,
D. T. Bishop
|
5 |
2015 |
5
🐜
|
