|
๐
|
Systematic identification of genomic markers of drug sensitivity in cancer cells
54 auth.
M. Garnett,
E. Edelman,
S. Heidorn,
C. Greenman,
A. Dastur,
K. Lau,
Patricia Greninger,
I. R. Thompson,
Xi Luo,
Jorge Soares,
Qingsong Liu,
F. Iorio,
D. Surdez,
Li Chen,
R. Milano,
...
G. Bignell,
A. T. Tam,
Helen R Davies,
Jesse A. Stevenson,
S. Barthorpe,
Stephen R. Lutz,
F. Kogera,
K. Lawrence,
Anne McLaren-Douglas,
Xeni Mitropoulos,
T. Mironenko,
Helen Thi,
L. Richardson,
Wenjun Zhou,
F.E.R. Jewitt,
Tinghu Zhang,
P. OโBrien,
Jessica L. Boisvert,
S. Price,
W. Hur,
Wanjuan Yang,
Xianming Deng,
A. Butler,
H. Choi,
J. Chang,
J. Baselga,
I. Stamenkovic,
J. Engelman,
Sreenath V. Sharma,
O. Delattre,
J. Saez-Rodriguez,
N. Gray,
J. Settleman,
P. Futreal,
D. Haber,
M. Stratton,
Sridhar Ramaswamy,
U. McDermott,
C. Benes
|
11 |
2012 |
11
๐
|
|
๐
|
Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes
130 auth.
Jacqueline K. White,
Anna-Karin B Gerdin,
N. Karp,
E. Ryder,
M. Buljan,
J. Bussell,
Jennifer Salisbury,
S. Clare,
N. Ingham,
C. Podrini,
Richard Houghton,
J. Estabel,
Joanna Bottomley,
David G. Melvin,
D. Sunter,
...
N. Adams,
Lauren Baker,
Caroline Barnes,
R. Beveridge,
E. Cambridge,
D. Carragher,
Prabhjoat S Chana,
Kay Clarke,
Y. Hooks,
N. Igosheva,
O. Ismail,
H. Jackson,
Leanne Kane,
R. Lacey,
D. Lafont,
M. Lucas,
Simon A. Maguire,
Katherine McGill,
R. McIntyre,
S. Messager,
Lynda Mottram,
Lee Mulderrig,
Selina Pearson,
Hayley J Protheroe,
Laura-Anne Roberson,
G. Salsbury,
Mark Sanderson,
Daniel Sanger,
Carl Shannon,
P. Thompson,
E. Tuck,
Valerie E. Vancollie,
L. Brackenbury,
Wendy Bushell,
Ross Cook,
P. Dalvi,
Diane Gleeson,
Bishoy Habib,
Matt Hardy,
Kifayathullah Liakath-Ali,
Evelina Miklejewska,
S. Price,
Debarati Sethi,
E. Trenchard,
Dominique von Schiller,
Sapna Vyas,
A. West,
J. Woodward,
Elizabeth H. Wynn,
Arthur Evans,
David J. Gannon,
M. Griffiths,
S. Holroyd,
V. Iyer,
Christian Kipp,
M. Lewis,
Wei Li,
Darren J. Oakley,
David Richardson,
D. Smedley,
Chukwuma A. Agu,
J. Bryant,
Liz Delaney,
Nadia I. Gueorguieva,
Helen Tharagonnet,
Anne Townsend,
D. Biggs,
Ellen Brown,
Adam Collinson,
Charles-Etienne Dumeau,
Evelyn Grau,
Sarah Harrison,
J. Harrison,
Catherine E. Ingle,
Helen Kundi,
A. Madich,
D. Mayhew,
Tom Metcalf,
Stuart Newman,
Johanna C. Pass,
L. Pearson,
Helen Reynolds,
Caroline Sinclair,
H. Wardle-Jones,
Michael Woods,
Liam Alexander,
Terry Brown,
Francesca Flack,
Carol Frost,
Nicola Griggs,
Silvia Hrnciarova,
Andrea Kirton,
J. Mcdermott,
C. Rogerson,
Gemma White,
Pawel Zielezinski,
Tia DiTommaso,
Andrew Edwards,
E. Heath,
Maryann Mahajan,
B. Yalcin,
D. Tannahill,
D. Logan,
D. MacArthur,
J. Flint,
V. Mahajan,
S. Tsang,
I. Smyth,
F. Watt,
W. Skarnes,
G. Dougan,
D. Adams,
R. RamรญrezโSolรญs,
A. Bradley,
K. Steel
|
8 |
2013 |
8
๐
|
|
๐
|
Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis
35 auth.
M. Petljak,
L. Alexandrov,
Jonathan S Brammeld,
S. Price,
D. Wedge,
Sebastian Grossmann,
K. Dawson,
Y. Ju,
F. Iorio,
J. Tubรญo,
C. Koh,
Ilias Georgakopoulos-Soares,
Bernardo Rodriguez-Martin,
Burรงak Otlu,
S. OโMeara,
...
A. Butler,
A. Menzies,
S. Bhosle,
K. Raine,
David Jones,
J. Teague,
Kathryn M Beal,
Calli Latimer,
L. OโNeill,
Jorge Zamora,
Elizabeth Anderson,
Nikita Patel,
M. Maddison,
B. Ng,
Jennifer Graham,
M. Garnett,
U. McDermott,
S. Nik-Zainal,
P. Campbell,
M. Stratton
|
8 |
2019 |
8
๐
|
|
๐
|
A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
26 auth.
R. Rad,
J. Cadiรฑanos,
Lena Rad,
I. Varela,
Alexander J. Strong,
Lydia Kriegl,
F. ConstantinoโCasas,
S. Eser,
Maren Hieber,
B. Seidler,
S. Price,
M. Fraga,
V. Calvanese,
Gary J. Hoffman,
H. Ponstingl,
...
G. Schneider,
K. Yusa,
C. Grove,
R. Schmid,
Wei Wang,
G. Vassiliou,
T. Kirchner,
U. McDermott,
Pentao Liu,
D. Saur,
A. Bradley
|
7 |
2013 |
7
๐
|
|
๐
|
The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils
26 auth.
M. Stammnitz,
Tim H. H. Coorens,
Kevin Gori,
D. Hayes,
B. Fu,
Jinhong Wang,
Daniel E. Martin-Herranz,
L. Alexandrov,
A. Baez-Ortega,
S. Barthorpe,
Alexandra Beck,
F. Giordano,
Graeme W. Knowles,
Y. Kwon,
George O. Hall,
...
S. Price,
Ruth J. Pye,
J. Tubรญo,
H. Siddle,
S. Sohal,
G. Woods,
U. McDermott,
Fengtang Yang,
M. Garnett,
Z. Ning,
E. Murchison
|
6 |
2018 |
6
๐
|
|
๐
|
Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells
24 auth.
T. Roumeliotis,
Steven P. Williams,
E. Gonรงalves,
Clara Alsinet,
M. Del Castillo Velasco-Herrera,
N. Aben,
F. Ghavidel,
M. Michaut,
Michael Schubert,
S. Price,
...
James C. Wright,
Lu Yu,
Mi Yang,
R. Dienstmann,
J. Guinney,
P. Beltrรฃo,
A. Brazma,
M. Pardo,
O. Stegle,
D. Adams,
L. Wessels,
J. Saez-Rodriguez,
U. McDermott,
J. Choudhary
|
6 |
2016 |
6
๐
|
|
๐
|
A resource of targeted mutant mouse lines for 5,061 genes
225 auth.
M. Birling,
A. Yoshiki,
D. Adams,
Shinya Ayabe,
A. Beaudet,
Joanna Bottomley,
A. Bradley,
Steve D. M. Brown,
Antje Buฬrger,
Wendy Bushell,
Francesco Chiani,
Hsian-Jean Chin,
Skevoulla Christou,
G. Codner,
F. DeMayo,
...
M. Dickinson,
B. Doe,
L. Donahue,
M. Fray,
A. Gambadoro,
Xiang Gao,
M. Gertsenstein,
A. Gomez-Segura,
L. Goodwin,
Jason D. Heaney,
Y. Hรฉrault,
M. D. de Angelis,
Si-Tse Jiang,
M. Justice,
P. Kasparek,
R. King,
R. Kรผhn,
Ho Lee,
Young Jae Lee,
Zhiwei Liu,
K. Lloyd,
I. Lorenzo,
A. Mallon,
C. McKerlie,
T. Meehan,
V. Fuentes,
Stuart Newman,
L. Nutter,
G. Oh,
G. Pavlovic,
R. RamรญrezโSolรญs,
B. Rosen,
E. Ryder,
Luis Santos,
Joel A. Schick,
J. Seavitt,
R. Sedlรกฤek,
C. Seisenberger,
J. Seong,
W. Skarnes,
T. Sorg,
K. Steel,
Masaru Tamura,
G. Tocchini-Valentini,
C. Wang,
H. Wardle-Jones,
Marie Wattenhofer-Donzรฉ,
S. Wells,
M. Wiles,
Brandon J. Willis,
J. A. Wood,
W. Wurst,
Ying Xu,
Juan J. Gallegos,
Jennie R. Green,
Ritu Bohat,
Katie Zimmel,
M. Pereira,
Suzanne MacMaster,
Sandra Tondat,
Linda Wei,
Tr Carroll,
Jorge Cabezas,
Fan-Lan Qing,
E. Jacob,
A. Creighton,
Patricia Castellanos-Penton,
Ozge Danisment,
Shannon Clarke,
Joanna Joeng,
Deborah Kelly,
Christine To,
Rebekah van Bruggen,
V. Gailus-Durner,
H. Fuchs,
S. Marschall,
S. Dunst,
Markus Romberger,
Bernhard Rey,
S. Fessele,
P. Gormanns,
R. Friedel,
Cornelia Kaloff,
A. Hรถrlein,
S. Teichmann,
Adriane Tasdemir,
Heidi Krause,
Dorota German,
A. Kรถnitzer,
Sarah Weber,
J. Beig,
M. Mckay,
Rick Bedigian,
S. Dion,
Peter M. Kutny,
Jennifer A Kelmenson,
Emily Perry,
Dong Nguyen-Bresinsky,
Audrie Seluke,
Tim Leach,
S. Perkins,
Amanda Slater,
Michael Petit,
Rachel Urban,
S. Kales,
M. DaCosta,
Michael Mcfarland,
Rick Palazola,
Kevin A. Peterson,
K. Svenson,
Robert E. Braun,
R. Taft,
Mark Rhue,
J. Garay,
Dave Clary,
Renee Araiza,
K. Grimsrud,
Lynette R. Bower,
Nicole L. Anchell,
K. Jager,
Diana L. Young,
P. T. Dao,
Wendy Gardiner,
Tonisha S. Bell,
J. Kenyon,
M. Stewart,
Denise E. Lynch,
Jorik Loeffler,
Adam Caulder,
Rosie Hillier,
M. M. Quwailid,
Rumana Zaman,
Luis Santos,
Y. Obata,
M. Iwama,
Hatsumi Nakata,
Tomomi Hashimoto,
Masayo Kadota,
H. Masuya,
Nobuhiko Tanaka,
Ikuo Miura,
Ikuko Yamada,
T. Furuse,
M. Selloum,
S. Jacquot,
A. Ayadi,
D. Ali-Hadji,
Philippe Charles,
E. le Marchand,
Amal El Amri,
Christelle Kujath,
Jean-Victor Fougerolle,
Peggy Mellul,
Sandrine Legeay,
Laurent Vasseur,
Anne-Isabelle Moro,
Romain Lorentz,
L. Schaeffer,
Dominique Dreyer,
Valรฉrie Erbs,
Benjamin Eisenmann,
G. Rossi,
Laurence Luppi,
A. Mertz,
Amรฉlie Jeanblanc,
E. Grau,
Caroline Sinclair,
Ellen Brown,
Helen Kundi,
A. Madich,
Mike Woods,
L. Pearson,
D. Mayhew,
Nicola Griggs,
Richard Houghton,
J. Bussell,
Catherine E. Ingle,
Sara Valentini,
Diane Gleeson,
Debarati Sethi,
T. Bayzetinova,
Jonathan Burvill,
Bishoy Habib,
Lauren Weavers,
R. Maswood,
Evelina Miklejewska,
Ross Cook,
Radka Platte,
S. Price,
Sapna Vyas,
Adam Collinson,
Matt Hardy,
P. Dalvi,
V. Iyer,
T. West,
Mark Thomas,
A. Mujica,
Elodie Sins,
Daniel Barrett,
Michael Dobbie,
A. Grobler,
G. Loots,
R. Hayeshi,
Liezl-Marie Scholtz,
Cor Bester,
W. Pheiffer,
K. Venter,
F. Bosch,
L. Teboul,
S. Murray
|
6 |
2021 |
6
๐
|
|
๐
|
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway
14 auth.
A. Chai,
Pei San Yee,
S. Price,
S. Yee,
Hui-Mei Lee,
Vivian Kh Tiong,
E. Gonรงalves,
F. Behan,
Jessica H Bateson,
James P. Gilbert,
...
A. Tan,
U. McDermott,
M. Garnett,
S. Cheong
|
4 |
2020 |
4
๐
|
|
๐
|
Comprehensive Pharmacogenomic Profiling of Malignant Pleural Mesothelioma Identifies a Subgroup Sensitive to FGFR Inhibition
13 auth.
Josine Quispel-Janssen,
J. Badhai,
L. Schunselaar,
S. Price,
Jonathan S Brammeld,
F. Iorio,
K. Kolluri,
M. Garnett,
A. Berns,
P. Baas,
...
U. McDermott,
J. Neefjes,
C. Alifrangis
|
4 |
2017 |
4
๐
|
|
๐
|
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
31 auth.
K. Kolluri,
C. Alifrangis,
Neelam Kumar,
Y. Ishii,
S. Price,
M. Michaut,
Steven P. Williams,
S. Barthorpe,
H. Lightfoot,
S. Busacca,
A. Sharkey,
Zhenqiang Yuan,
E. Sage,
S. Vallath,
J. Le Quesne,
...
D. Tice,
D. Alrifai,
S. von Karstedt,
A. Montinaro,
N. Guppy,
D. Waller,
A. Nakas,
R. Good,
A. Holmes,
H. Walczak,
D. Fennell,
M. Garnett,
F. Iorio,
L. Wessels,
U. McDermott,
S. Janes
|
4 |
2018 |
4
๐
|
|
๐
|
Minimal genome-wide human CRISPR-Cas9 library
17 auth.
E. Gonรงalves,
Mark Thomas,
F. Behan,
G. Picco,
C. Pacini,
Felicity Allen,
A. Vinceti,
Mamta Sharma,
D. Jackson,
S. Price,
...
C. Beaver,
O. Dovey,
D. Parry-Smith,
F. Iorio,
L. Parts,
K. Yusa,
M. Garnett
|
4 |
2021 |
4
๐
|
