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🐜
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Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)
14 auth.
Eric L. Van Nostrand,
G. Pratt,
Alexander A. Shishkin,
C. Gelboin-Burkhart,
Mark Y. Fang,
B. Sundararaman,
S. Blue,
Thai B. Nguyen,
Christine Surka,
Keri Elkins,
...
Rebecca Stanton,
F. Rigo,
M. Guttman,
Gene W. Yeo
|
10 |
2016 |
10
🐜
|
|
🐜
|
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
21 auth.
Christopher J. Donnelly,
Ping-Wu Zhang,
Jacqueline T. Pham,
A. Haeusler,
Nipun A. Mistry,
Svetlana Vidensky,
E. Daley,
E. M. Poth,
Benjamin Hoover,
Daniel M. Fines,
...
N. Maragakis,
P. Tienari,
L. Petrucelli,
B. Traynor,
B. Traynor,
Jiou Wang,
F. Rigo,
C. Bennett,
S. Blackshaw,
R. Sattler,
J. Rothstein
|
9 |
2013 |
9
🐜
|
|
🐜
|
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
14 auth.
Richard S. Finkel,
C. Chiriboga,
J. Vajsar,
J. Day,
J. Montes,
D. D. De Vivo,
M. Yamashita,
F. Rigo,
G. Hung,
E. Schneider,
...
Daniel A. Norris,
S. Xia,
C. F. Bennett,
K. Bishop
|
9 |
2016 |
9
🐜
|
|
🐜
|
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
20 auth.
D. Sareen,
J. O’Rourke,
P. Meera,
A. Muhammad,
Sharday Grant,
M. Simpkinson,
S. Bell,
S. Carmona,
L. Ornelas,
Anais Sahabian,
...
T. Gendron,
L. Petrucelli,
Michael W. Baughn,
J. Ravits,
M. Harms,
F. Rigo,
C. Bennett,
T. Otis,
C. Svendsen,
R. Baloh
|
9 |
2013 |
9
🐜
|
|
🐜
|
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model.
7 auth.
Y. Hua,
K. Sahashi,
G. Hung,
F. Rigo,
M. Passini,
C. Bennett,
...
A. Krainer
|
9 |
2010 |
9
🐜
|
|
🐜
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Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
30 auth.
C. Lagier-Tourenne,
Michael W. Baughn,
F. Rigo,
Shuying Sun,
Patrick P. Liu,
Hai-Ri Li,
Jie Jiang,
A. Watt,
S. Chun,
Melanie Katz,
J. Qiu,
Ying Sun,
Shuo-Chien Ling,
Qiang Zhu,
M. Polymenidou,
...
Kevin Drenner,
Jonathan W. Artates,
Melissa McAlonis-Downes,
Sebastian J. Markmiller,
Kasey R. Hutt,
D. Pizzo,
J. Cady,
M. Harms,
R. Baloh,
S. Vandenberg,
Gene W. Yeo,
Xiang-Dong Fu,
C. Bennett,
D. Cleveland,
J. Ravits
|
9 |
2013 |
9
🐜
|
|
🐜
|
Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy
15 auth.
M. Passini,
J. Bu,
A. Richards,
Cathrine Kinnecom,
S. Sardi,
L. Stanek,
Y. Hua,
F. Rigo,
J. Matson,
G. Hung,
...
E. Kaye,
L. Shihabuddin,
A. Krainer,
C. Bennett,
Seng H. Cheng
|
8 |
2011 |
8
🐜
|
|
🐜
|
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
41 auth.
Jie Jiang,
Qiang Zhu,
Tania F. Gendron,
Shahram Saberi,
Melissa McAlonis-Downes,
A. Seelman,
J. Stauffer,
P. Jafar‐nejad,
Kevin Drenner,
Derek Schulte,
S. Chun,
Shuying Sun,
Shuo-Chien Ling,
Brian Myers,
J. Engelhardt,
...
Melanie Katz,
Michael W. Baughn,
O. Platoshyn,
M. Marsala,
A. Watt,
C. Heyser,
M. Ard,
Louis De Muynck,
Lillian M. Daughrity,
Debbie Swing,
L. Tessarollo,
Chris J. Jung,
Arnaud Delpoux,
Daniel T. Utzschneider,
Stephen M. Hedrick,
Pieter J. de Jong,
D. Edbauer,
Philip Van Damme,
L. Petrucelli,
Christopher E. Shaw,
C. F. Bennett,
Sandrine Da Cruz,
J. Ravits,
F. Rigo,
Don W. Cleveland,
C. Lagier-Tourenne
|
8 |
2016 |
8
🐜
|
|
🐜
|
Therapeutic reduction of ataxin 2 extends lifespan and reduces pathology in TDP-43 mice
14 auth.
Lindsay A. Becker,
Brenda Huang,
Gregor Bieri,
Rosanna K. Ma,
David A. Knowles,
P. Jafar‐nejad,
James Messing,
Hong-Joo Kim,
Armand Soriano,
G. Auburger,
...
S. Pulst,
J. Taylor,
F. Rigo,
A. Gitler
|
8 |
2017 |
8
🐜
|
|
🐜
|
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
20 auth.
Ze’ev Melamed,
Jone López-Erauskin,
Michael W. Baughn,
Ouyang Zhang,
Kevin Drenner,
Ying Sun,
F. Freyermuth,
Moira A. McMahon,
Melinda S. Beccari,
Jonathan W. Artates,
...
T. Ohkubo,
Maria J. Rodriguez,
Nianwei Lin,
Dongmei Wu,
C. F. Bennett,
F. Rigo,
S. Da Cruz,
J. Ravits,
C. Lagier-Tourenne,
Don W. Cleveland
|
8 |
2018 |
8
🐜
|
|
🐜
|
Peripheral SMN restoration is essential for long-term rescue of a severe SMA mouse model
7 auth.
Y. Hua,
K. Sahashi,
F. Rigo,
G. Hung,
G. Horev,
C. F. Bennett,
...
A. Krainer
|
8 |
2011 |
8
🐜
|
|
🐜
|
The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing
17 auth.
G. Barry,
J. Briggs,
D. Vanichkina,
E. M. Poth,
N. Beveridge,
V. Ratnu,
S. Nayler,
K. Nones,
J. Hu,
T. Bredy,
...
S. Nakagawa,
F. Rigo,
R. Taft,
M. Cairns,
S. Blackshaw,
E. Wolvetang,
J. Mattick
|
8 |
2014 |
8
🐜
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