|
🐜
|
Initial sequencing and analysis of the human genome.
256 auth.
E. Lander,
L. Linton,
B. Birren,
C. Nusbaum,
M. Zody,
J. Baldwin,
K. Devon,
K. Dewar,
M. Doyle,
W. Fitzhugh,
R. Funke,
D. Gage,
K. Harris,
A. Heaford,
J. Howland,
...
L. Kann,
J. Lehoczky,
R. Levine,
P. McEwan,
K. McKernan,
J. Meldrim,
J. Mesirov,
C. Miranda,
W. Morris,
J. Naylor,
C. Raymond,
M. Rosetti,
R. Santos,
A. Sheridan,
C. Sougnez,
Y. Stange-Thomann,
N. Stojanovic,
A. Subramanian,
D. Wyman,
J. Rogers,
J. Sulston,
R. Ainscough,
S. Beck,
D. Bentley,
J. Burton,
C. Clee,
N. Carter,
A. Coulson,
R. Deadman,
P. Deloukas,
A. Dunham,
I. Dunham,
R. Durbin,
L. French,
D. Grafham,
S. Gregory,
T. Hubbard,
S. Humphray,
A. Hunt,
M. Jones,
C. Lloyd,
A. McMurray,
L. Matthews,
S. Mercer,
S. Milne,
J. Mullikin,
A. Mungall,
R. Plumb,
M. Ross,
R. Shownkeen,
S. Sims,
R. Waterston,
R. Wilson,
L. Hillier,
J. McPherson,
M. Marra,
E. Mardis,
L. Fulton,
A. Chinwalla,
K. Pepin,
W. Gish,
S. Chissoe,
M. Wendl,
K. Delehaunty,
T. Miner,
A. Delehaunty,
J. Kramer,
L. Cook,
R. Fulton,
D. Johnson,
P. Minx,
S. Clifton,
T. Hawkins,
E. Branscomb,
P. Predki,
P. Richardson,
S. Wenning,
T. Slezak,
N. Doggett,
J. Cheng,
A. Olsen,
S. Lucas,
C. Elkin,
E. Uberbacher,
M. Frazier,
R. Gibbs,
D. Muzny,
S. Scherer,
J. Bouck,
E. Sodergren,
K. Worley,
C. Rives,
J. H. Gorrell,
M. Metzker,
S. Naylor,
R. Kucherlapati,
D. Nelson,
G. Weinstock,
Y. Sakaki,
A. Fujiyama,
M. Hattori,
T. Yada,
A. Toyoda,
T. Itoh,
C. Kawagoe,
H. Watanabe,
Y. Totoki,
T. Taylor,
J. Weissenbach,
R. Heilig,
W. Saurin,
F. Artiguenave,
P. Brottier,
T. Bruls,
É. Pelletier,
C. Robert,
P. Wincker,
D. Smith,
L. Doucette-Stamm,
M. Rubenfield,
K. Weinstock,
H. M. Lee,
J. Dubois,
A. Rosenthal,
M. Platzer,
G. Nyakatura,
S. Taudien,
A. Rump,
H. Yang,
J. Yu,
J. Wang,
G. Huang,
J. Gu,
L. Hood,
L. Rowen,
A. Madan,
S. Qin,
R. W. Davis,
N. Federspiel,
A. Abola,
M. Proctor,
R. M. Myers,
J. Schmutz,
M. Dickson,
J. Grimwood,
D. Cox,
M. Olson,
R. Kaul,
N. Shimizu,
K. Kawasaki,
S. Minoshima,
G. Evans,
M. Athanasiou,
R. Schultz,
B. Roe,
F. Chen,
H. Pan,
J. Ramser,
H. Lehrach,
R. Reinhardt,
W. McCombie,
M. de la Bastide,
N. Dedhia,
H. Blöcker,
K. Hornischer,
G. Nordsiek,
R. Agarwala,
L. Aravind,
J. Bailey,
A. Bateman,
S. Batzoglou,
E. Birney,
P. Bork,
D. Brown,
C. Burge,
L. Cerutti,
H. Chen,
D. Church,
M. Clamp,
R. Copley,
T. Doerks,
S. Eddy,
E. Eichler,
T. Furey,
J. Galagan,
J. Gilbert,
C. Harmon,
Y. Hayashizaki,
D. Haussler,
H. Hermjakob,
K. Hokamp,
W. Jang,
L. S. Johnson,
T. A. Jones,
S. Kasif,
A. Kaspryzk,
S. Kennedy,
W. Kent,
P. Kitts,
E. Koonin,
I. Korf,
D. Kulp,
D. Lancet,
Gwênlyn Glusman,
T. Lowe,
A. McLysaght,
T. Mikkelsen,
J. V. Moran,
N. Mulder,
V. J. Pollara,
C. Ponting,
G. Schuler,
J. Schultz,
G. Slater,
A. Smit,
E. Stupka,
J. Szustakowki,
D. Thierry-Mieg,
J. Thierry-Mieg,
L. Wagner,
J. Wallis,
R. Wheeler,
A. Williams,
Y. I. Wolf,
K. H. Wolfe,
S. Yang,
R. Yeh,
F. Collins,
M. Guyer,
J. Peterson,
A. Felsenfeld,
K. Wetterstrand,
A. Patrinos,
M. Morgan,
P. D. de Jong,
J. Catanese,
K. Osoegawa,
H. Shizuya,
S. Choi,
Y. J. Chen,
Vacslav Glukhov
|
13 |
2001 |
13
🐜
|
|
🐜
|
Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921))
255 auth.
E. Lander,
L. Linton,
B. Birren,
C. Nusbaum,
M. Zody,
J. Baldwin,
K. Devon,
K. Dewar,
M. Doyle,
W. Fitzhugh,
R. Funke,
D. Gage,
K. Harris,
A. Heaford,
J. Howland,
...
L. Kann,
J. Lehoczky,
R. Levine,
P. McEwan,
K. McKernan,
J. Meldrim,
J. Mesirov,
C. Miranda,
W. Morris,
J. Naylor,
C. Raymond,
M. Rosetti,
R. Santos,
A. Sheridan,
C. Sougnez,
N. Stange-thomann,
N. Stojanovic,
A. Subramanian,
D. Wyman,
J. Rogers,
J. Sulston,
R. Ainscough,
S. Beck,
D. Bentley,
J. Burton,
C. Clee,
N. Carter,
A. Coulson,
R. Deadman,
P. Deloukas,
A. Dunham,
I. Dunham,
R. Durbin,
L. French,
D. Grafham,
S. Gregory,
T. Hubbard,
S. Humphray,
A. Hunt,
M. Jones,
C. Lloyd,
A. McMurray,
L. Matthews,
S. Mercer,
S. Milne,
J. Mullikin,
A. Mungall,
R. Plumb,
M. Ross,
R. Shownkeen,
S. Sims,
R. Waterston,
R. Wilson,
L. Hillier,
J. McPherson,
M. Marra,
E. Mardis,
L. Fulton,
A. Chinwalla,
K. Pepin,
W. Gish,
S. Chissoe,
M. Wendl,
K. Delehaunty,
T. Miner,
A. Delehaunty,
J. Kramer,
L. Cook,
R. Fulton,
D. Johnson,
P. Minx,
S. Clifton,
T. Hawkins,
E. Branscomb,
P. Predki,
P. Richardson,
S. Wenning,
T. Slezak,
N. Doggett,
Jan-Fang Cheng,
A. Olsen,
S. Lucas,
C. Elkin,
E. Uberbacher,
M. Frazier,
R. Gibbs,
D. Muzny,
S. Scherer,
J. Bouck,
E. Sodergren,
K. Worley,
C. Rives,
J. H. Gorrell,
M. Metzker,
S. Naylor,
R. Kucherlapati,
D. Nelson,
G. Weinstock,
Y. Sakaki,
A. Fujiyama,
M. Hattori,
T. Yada,
A. Toyoda,
T. Itoh,
C. Kawagoe,
Hidemi Watanabe,
Y. Totoki,
T. Taylor,
J. Weissenbach,
R. Heilig,
W. Saurin,
F. Artiguenave,
P. Brottier,
T. Brüls,
É. Pelletier,
C. Robert,
P. Wincker,
A. Rosenthal,
M. Platzer,
G. Nyakatura,
S. Taudien,
A. Rump,
Douglas Smith,
L. Doucette-Stamm,
M. Rubenfield,
K. Weinstock,
M. Hong,
J. Dubois,
Huanming Yang,
Jun Yu,
Jian Wang,
G. Huang,
J. Gu,
L. Hood,
L. Rowen,
A. Madan,
S. Qin,
Ronald W. Davis,
N. Federspiel,
A. Abola,
M. Proctor,
B. Roe,
Feng Chen,
H. Pan,
J. Ramser,
H. Lehrach,
R. Reinhardt,
W. McCombie,
M. Bastide,
N. Dedhia,
H. Blöcker,
K. Hornischer,
G. Nordsiek,
R. Agarwala,
L. Aravind,
J. Bailey,
A. Bateman,
S. Batzoglou,
E. Birney,
P. Bork,
Daniel G. Brown,
C. Burge,
L. Cerutti,
Hsiu-Chuan Chen,
D. Church,
M. Clamp,
R. Copley,
T. Doerks,
S. Eddy,
E. Eichler,
T. Furey,
J. Galagan,
J. Gilbert,
C. Harmon,
Y. Hayashizaki,
D. Haussler,
H. Hermjakob,
K. Hokamp,
W. Jang,
L. S. Johnson,
T. A. Jones,
S. Kasif,
A. Kaspryzk,
S. Kennedy,
W. Kent,
P. Kitts,
E. Koonin,
I. Korf,
D. Kulp,
D. Lancet,
T. Lowe,
A. McLysaght,
T. Mikkelsen,
J. V. Moran,
N. Mulder,
V. J. Pollara,
C. Ponting,
G. Schuler,
J. Schultz,
G. Slater,
A. Smit,
E. Stupka,
J. Szustakowki,
D. Thierry-Mieg,
J. Thierry-Mieg,
L. Wagner,
J. Wallis,
R. Wheeler,
Alan Williams,
Y. Wolf,
K. H. Wolfe,
Shiaw-Pyng Yang,
R. Yeh,
F. Collins,
M. Guyer,
Jane L. Peterson,
A. Felsenfeld,
K. Wetterstrand,
R. Myers,
J. Schmutz,
M. Dickson,
J. Grimwood,
D. Cox,
M. Olson,
R. Kaul,
Christopher K. Raymond,
N. Shimizu,
K. Kawasaki,
S. Minoshima,
G. Evans,
M. Athanasiou,
R. Schultz,
A. Patrinos,
M. Morgan,
P. Jong,
J. Catanese,
K. Osoegawa,
H. Shizuya,
Sangdun Choi,
Yu Chen
|
6 |
2001 |
6
🐜
|
|
🐜
|
Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity
10 auth.
S. Fanning,
L. Hodges-Gallagher,
D. Myles,
R. Sun,
C. Fowler,
I. N. Plant,
...
B. Green,
C. Harmon,
Geoffrey L. Greene,
Peter J Kushner
|
5 |
2018 |
5
🐜
|
|
🐜
|
Genoviz Software Development Kit: Java tool kit for building genomics visualization applications
8 auth.
G. Helt,
John W. Nicol,
E. Erwin,
Eric Blossom,
Steven G. Blanchard,
S. Chervitz,
...
C. Harmon,
A. Loraine
|
4 |
2009 |
4
🐜
|
|
🦁
|
Comparative Analysis of Spatial Patterns of Gene Expression in Drosophila melanogaster Imaginal Discs
7 auth.
C. Harmon,
P. Ahammad,
A. Hammonds,
Richard Weiszmann,
S. Celniker,
S. Sastry,
...
G. Rubin
|
4 |
2007 |
4
🦁
|
|
🐜
|
Abstract P1-17-12: Preliminary data from a phase I/II, multicenter, dose escalation study of OP-1250, an oral CERAN/SERD, in subjects with advanced and/or metastatic estrogen receptor (ER)-positive, HER2-negative breast cancer
15 auth.
M. Patel,
C. Alemany,
Zahi I. Mitri,
D. Makower,
V. Borges,
J. Sparano,
Trinh L. Le,
P. Klein,
J. Lawrence,
P. Kushner,
...
D. Faltaos,
C. Harmon,
David Myles,
J. Zujewski,
E. Hamilton
|
3 |
2022 |
3
🐜
|
|
🐬
|
Joint nonparametric alignment for analyzing spatial gene expression patterns in Drosophila imaginal discs
P. Ahammad,
C. Harmon,
A. Hammonds,
S. Sastry,
G. Rubin
|
3 |
2005 |
3
🐬
|
|
🐢
|
Palazestrant (OP-1250), A Complete Estrogen Receptor Antagonist, Inhibits Wild-type and Mutant ER-positive Breast Cancer Models as Monotherapy and in Combination
13 auth.
Alison D Parisian,
Susanna A Barratt,
L. Hodges-Gallagher,
Fabián Ortega,
Guadalupe Peña,
Judevin Sapugay,
Brandon Robello,
R. Sun,
David Kulp,
Gopinath S Palanisamy,
...
David C Myles,
Peter J Kushner,
C. Harmon
|
2 |
2023 |
2
🐢
|
|
🐜
|
OP-1250: A potent orally available complete antagonist of estrogen receptor-mediated signaling that shrinks wild type and mutant breast tumors
7 auth.
L. Hodges-Gallagher,
R. Sun,
D. Myles,
P. Klein,
J. Zujewski,
C. Harmon,
...
P. Kushner
|
2 |
2020 |
2
🐜
|
|
🐬
|
Abstract 4376: OP-1250, a complete estrogen receptor antagonist (CERAN) that shrinks estrogen receptor positive tumors and exhibits favorable pharmacokinetics
L. Hodges-Gallagher,
C. Harmon,
R. Sun,
D. Myles,
P. Kushner
|
2 |
2020 |
2
🐬
|
|
🐜
|
Abstract LB122: The complete estrogen receptor antagonist (CERAN) OP-1250 shrinks ER+ brain metastases in an intracranial xenograft tumor model expressing mutant ESR1
7 auth.
L. Hodges-Gallagher,
Alison D. Parisian,
R. Sun,
D. Myles,
P. Klein,
C. Harmon,
...
P. Kushner
|
1 |
2021 |
1
🐜
|
|
🐬
|
Abstract P5-05-02: Preclinical development of OP-1250, an oral complete estrogen receptor antagonist (CERAN) that shrinks ER-positive breast tumors in xenograft models
L. Hodges-Gallagher,
R. Sun,
D. Myles,
C. Harmon,
P. Kushner
|
1 |
2020 |
1
🐬
|
|
🐜
|
Abstract PS18-16: The complete estrogen receptor antagonist OP-1250 shrinks tumors in xenograft models and has favorable preclinical pharmacokinetic attributes
7 auth.
L. Hodges-Gallagher,
R. Sun,
D. Myles,
P. Klein,
J. Zujewski,
C. Harmon,
...
P. Kushner
|
1 |
2021 |
1
🐜
|
