|
π
|
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.
266 auth.
Benjamin J. Raphael,
R. Hruban,
A. Aguirre,
R. Moffitt,
J. Yeh,
C. Stewart,
A. G. Robertson,
A. Cherniack,
M. Gupta,
G. Getz,
S. Gabriel,
M. Meyerson,
C. Cibulskis,
S. Fei,
T. Hinoue,
...
Hui Shen,
P. Laird,
Shiyun Ling,
Yiling Lu,
G. Mills,
Rehan Akbani,
Phillipe Loher,
Eric Londin,
I. Rigoutsos,
Aristeidis G. Telonis,
E. Gibb,
A. Goldenberg,
A. Mezlini,
K. Hoadley,
E. Collisson,
E. Lander,
Bradley A. Murray,
J. Hess,
Mara W Rosenberg,
Louis Bergelson,
Hailei Zhang,
Juok Cho,
G. Tiao,
Jaegil Kim,
D. Livitz,
I. Leshchiner,
B. Reardon,
E. Allen,
A. Kamburov,
R. Beroukhim,
G. Saksena,
S. Schumacher,
M. Noble,
David I Heiman,
Nils Gehlenborg,
M. Lawrence,
V. Adsay,
G. Petersen,
D. Klimstra,
N. Bardeesy,
Mark D. M. Leiserson,
R. Bowlby,
K. Kasaian,
I. Birol,
K. Mungall,
S. Sadeghi,
J. Weinstein,
P. Spellman,
Yuexin Liu,
L. Amundadottir,
J. Tepper,
A. Singhi,
R. Dhir,
Drwiega Paul,
T. Smyrk,
Lizhi Zhang,
Paula Kim,
Jay Bowen,
J. Frick,
J. Gastier-Foster,
M. Gerken,
Kevin R Lau,
K. Leraas,
T. Lichtenberg,
N. Ramirez,
Jeremy Renkel,
M. Sherman,
L. Wise,
P. Yena,
E. Zmuda,
J. Shih,
Adrian Ally,
M. Balasundaram,
R. Carlsen,
Andy Chu,
E. Chuah,
A. Clarke,
Noreen Dhalla,
R. Holt,
Steven J. M. Jones,
Darlene Lee,
Yussanne Ma,
M. Marra,
Michael Mayo,
Richard A. Moore,
A. Mungall,
J. Schein,
Payal Sipahimalani,
Angela Tam,
N. Thiessen,
Kane Tse,
Tina Wong,
Denise Brooks,
J. Auman,
S. Balu,
T. Bodenheimer,
D. Hayes,
A. Hoyle,
S. Jefferys,
Corbin D. Jones,
S. Meng,
P. Mieczkowski,
Lisle E. Mose,
C. Perou,
Amy H. Perou,
J. Roach,
Yan Shi,
J. Simons,
Tara J. Skelly,
Matthew G. Soloway,
Donghui Tan,
Umadevi Veluvolu,
J. Parker,
M. Wilkerson,
Anil Korkut,
Y. ΕenbabaoΔlu,
P. Burch,
R. McWilliams,
K. G. Chaffee,
A. Oberg,
Wei Zhang,
M. Gingras,
D. Wheeler,
Liu Xi,
Monique Albert,
J. Bartlett,
H. Sekhon,
Y. Stephen,
Zaren Howard,
M. Judy,
A. Breggia,
R. Shroff,
Sudha Chudamani,
Jia Liu,
Laxmi Lolla,
R. Naresh,
T. Pihl,
Qiang Sun,
Yunhu Wan,
Ye Wu,
Smith Jennifer,
K. Roggin,
K. Becker,
M. Behera,
Joseph Bennett,
L. Boice,
E. Burks,
C. G. C. JΓΊnior,
J. Chabot,
D. Tirapelli,
J. S. Santos,
M. Dubina,
J. Eschbacher,
Meijuan Huang,
L. Huelsenbeck-Dill,
R. Jenkins,
A. Karpov,
R. Kemp,
V. Lyadov,
S. Maithel,
G. Manikhas,
E. Montgomery,
H. Noushmehr,
A. Osunkoya,
T. Owonikoko,
O. Paklina,
O. Potapova,
S. Ramalingam,
W. Rathmell,
K. Rieger-Christ,
Charles Saller,
G. Setdikova,
A. Shabunin,
G. Sica,
T. Su,
T. Sullivan,
P. Swanson,
Katherine Tarvin,
M. Tavobilov,
L. Thorne,
S. Urbanski,
Olga Voronina,
Timothy C. Wang,
D. Crain,
Erin E. Curley,
J. Gardner,
D. Mallery,
S. Morris,
J. Paulauskis,
R. Penny,
C. Shelton,
T. Shelton,
K. Janssen,
O. Bathe,
N. Bahary,
J. Slotta-Huspenina,
A. Johns,
H. Hibshoosh,
R. Hwang,
A. Sepulveda,
Amie Radenbaugh,
S. Baylin,
Mario Berrios,
Moiz Bootwalla,
Andrea E Holbrook,
Phillip H. Lai,
D. Maglinte,
S. Mahurkar,
T. Triche,
D. V. Berg,
D. Weisenberger,
L. Chin,
R. Kucherlapati,
M. Kucherlapati,
A. Pantazi,
P. Park,
Douglas Voet,
Pei Lin,
S. Frazer,
T. DeFreitas,
S. Meier,
S. Kwon,
Y. Kim,
Sang Jae Park,
Sung-Sik Han,
S. Kim,
H. Kim,
E. Furth,
M. Tempero,
C. Sander,
A. Biankin,
D. Chang,
Peter Bailey,
A. Gill,
J. Kench,
S. Grimmond,
R. Postier,
R. Zuna,
H. Sicotte,
John A. Demchok,
M. Ferguson,
C. Hutter,
K. Shaw,
Margi Sheth,
H. Sofia,
R. Tarnuzzer,
Zhining Wang,
Liming Yang,
J. Zhang,
Ina Felau,
J. Zenklusen
|
10 |
2017 |
10
π
|
|
π
|
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
40 auth.
V. Viswanathan,
M. Ryan,
Harshil Dhruv,
S. Gill,
O. Eichhoff,
B. Seashore-Ludlow,
S. Kaffenberger,
J. Eaton,
K. Shimada,
A. Aguirre,
S. Viswanathan,
S. Chattopadhyay,
P. Tamayo,
W. Yang,
M. Rees,
...
Sixun Chen,
Z. Boskovic,
Sarah Javaid,
Cherrie Huang,
Xiaoyun Wu,
Yuen-Yi Tseng,
E. Roider,
D. Gao,
J. Cleary,
B. Wolpin,
J. Mesirov,
D. Haber,
J. Engelman,
J. Boehm,
J. Kotz,
C. Hon,
Yu Chen,
W. Hahn,
M. Levesque,
John G Doench,
M. Berens,
Alykhan F. Shamji,
P. Clemons,
B. Stockwell,
S. Schreiber
|
10 |
2017 |
10
π
|
|
π
|
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer
29 auth.
S. Bullman,
C. Pedamallu,
E. Sicinska,
T. Clancy,
Xiaoyang Zhang,
D. Cai,
D. Neuberg,
Katherine Huang,
F. Guevara,
T. Nelson,
Otari Chipashvili,
Timothy Hagan,
M. Walker,
A. Ramachandran,
B. Diosdado,
...
G. Serna,
N. Mulet,
S. Landolfi,
S. RamΓ³n y. Cajal,
R. Fasani,
A. Aguirre,
K. Ng,
E. Γlez,
S. Ogino,
J. Tabernero,
C. Fuchs,
W. Hahn,
P. Nuciforo,
M. Meyerson
|
10 |
2017 |
10
π
|
|
π¦
|
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
8 auth.
A. Aguirre,
N. Bardeesy,
M. Sinha,
L. Lopez,
D. Tuveson,
J. Horner,
...
M. Redston,
R. DePinho
|
9 |
2003 |
9
π¦
|
|
π
|
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
9 auth.
N. Sharpless,
N. Bardeesy,
KeeβHo Lee,
D. Carrasco,
D. Castrillon,
A. Aguirre,
...
Emily Wu,
J. Horner,
R. DePinho
|
9 |
2001 |
9
π
|
|
π
|
Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
70 auth.
HervΓ© Tiriac,
P. Belleau,
Dannielle D. Engle,
Dennis Plenker,
Astrid DeschΓͺnes,
T. Somerville,
F. Froeling,
R. Burkhart,
R. Denroche,
G. Jang,
K. Miyabayashi,
C. Young,
Hardik Patel,
M. Ma,
Joseph F. LaComb,
...
R. L. Palmaira,
A. Javed,
Jasmine C Huynh,
Molly E. Johnson,
K. Arora,
N. Robine,
Minita J. Shah,
R. Sanghvi,
Austin B. Goetz,
Cinthya Y Lowder,
L. Martello,
E. Driehuis,
N. Lecomte,
G. Askan,
C. Iacobuzio-Donahue,
H. Clevers,
L. Wood,
R. Hruban,
E. Thompson,
A. Aguirre,
B. Wolpin,
A. Sasson,
Joseph Kim,
Maoxin Wu,
J. Bucobo,
P. Allen,
D. Sejpal,
W. Nealon,
James D Sullivan,
J. Winter,
P. Gimotty,
J. Grem,
D. Dimaio,
J. Buscaglia,
P. Grandgenett,
J. Brody,
M. Hollingsworth,
G. OβKane,
F. Notta,
Edward J. Kim,
J. M. Crawford,
C. Devoe,
A. Ocean,
elliot k fishman,
Kenneth H. Yu,
Ellen Li,
C. Vakoc,
B. Hubert,
S. Fischer,
Julie M. Wilson,
R. Moffitt,
J. Knox,
A. Krasnitz,
S. Gallinger,
D. Tuveson
|
9 |
2018 |
9
π
|
|
π
|
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
14 auth.
N. Bardeesy,
A. Aguirre,
Gerald C. Chu,
Kuang-Hung Cheng,
L. Lopez,
A. Hezel,
Bin Feng,
C. Brennan,
R. Weissleder,
U. Mahmood,
...
D. Hanahan,
M. Redston,
L. Chin,
R. DePinho
|
9 |
2006 |
9
π
|
|
π¦
|
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting.
30 auth.
A. Aguirre,
R. Meyers,
B. Weir,
F. Vazquez,
C.-z. Zhang,
U. Ben-David,
A. Cook,
G. Ha,
W. Harrington,
M. Doshi,
M. KostβAlimova,
S. Gill,
H. Xu,
L. Ali,
G. Jiang,
...
S. Pantel,
Y. Lee,
A. Goodale,
A. Cherniack,
C. Oh,
G. Kryukov,
G. Cowley,
L. Garraway,
K. Stegmaier,
C. Roberts,
T. Golub,
M. Meyerson,
D. Root,
Aviad Tsherniak,
W. Hahn
|
8 |
2016 |
8
π¦
|
|
π
|
High-resolution genomic profiles of human lung cancer.
15 auth.
G. Tonon,
Kwok-kin Wong,
G. Maulik,
C. Brennan,
Bin Feng,
Yunyu Zhang,
D. Khatry,
A. Protopopov,
M. J. You,
A. Aguirre,
...
E. Martin,
Zhaohui Yang,
H. Ji,
L. Chin,
R. DePinho
|
8 |
2005 |
8
π
|
|
π
|
Spatially organized multicellular immune hubs in human colorectal cancer
72 auth.
K. Pelka,
Matan Hofree,
Jonathan H. Chen,
Siranush Sarkizova,
Joshua D. Pirl,
Vjola Jorgji,
Alborz Bejnood,
Danielle Dionne,
William Ge,
Katherine H Xu,
S. Chao,
D. Zollinger,
David J. Lieb,
J. Reeves,
C. Fuhrman,
...
M. Hoang,
T. Delorey,
Lan Nguyen,
Julia Waldman,
M. Klapholz,
Isaac Wakiro,
Ofir Cohen,
Julian J Albers,
C. Smillie,
Michael S. Cuoco,
Jingyi Wu,
Mei-ju Su,
J. Yeung,
B. Vijaykumar,
Angela M. Magnuson,
Natasha Asinovski,
Tabea Moll,
Max N. Goder-Reiser,
Anise S. Applebaum,
L. Brais,
L. Dellostritto,
Sarah L. Denning,
S. Phillips,
Emma K. Hill,
Julia K. Meehan,
Dennie T. Frederick,
T. Sharova,
Abhay Kanodia,
E. Todres,
Judit JanΓ©-Valbuena,
M. Biton,
B. Izar,
C. Lambden,
T. Clancy,
R. Bleday,
N. Melnitchouk,
J. Irani,
H. Kunitake,
D. Berger,
A. Srivastava,
J. Hornick,
S. Ogino,
Asaf Rotem,
S. Vigneau,
B. Johnson,
R. Corcoran,
A. Sharpe,
V. Kuchroo,
K. Ng,
M. Giannakis,
Linda T. Nieman,
G. Boland,
A. Aguirre,
A. Anderson,
O. Rozenblatt-Rosen,
A. Regev,
N. Hacohen
|
8 |
2021 |
8
π
|
|
π
|
Mutational processes shape the landscape of TP53 mutations in human cancer
27 auth.
Andrew O. Giacomelli,
Xiaoping Yang,
Robert E. Lintner,
James M. McFarland,
Marc Duby,
Jaegil Kim,
Thomas P. Howard,
D. Takeda,
S. H. Ly,
Eejung Kim,
Hugh S. Gannon,
Brian Hurhula,
Ted Sharpe,
A. Goodale,
Briana Fritchman,
...
S. Steelman,
F. Vazquez,
Aviad Tsherniak,
A. Aguirre,
John G Doench,
F. Piccioni,
C. Roberts,
M. Meyerson,
G. Getz,
Cory M. Johannessen,
D. Root,
W. Hahn
|
8 |
2018 |
8
π
|
|
π
|
ARID1B is a specific vulnerability in ARID1A-mutant cancers
15 auth.
Katherine C. Helming,
Xiaofeng Wang,
B. Wilson,
F. Vazquez,
Jeffrey R. Haswell,
Haley E Manchester,
Youngha Kim,
G. Kryukov,
M. Ghandi,
A. Aguirre,
...
Zainab Jagani,
Zhong Wang,
L. Garraway,
W. Hahn,
C. Roberts
|
8 |
2014 |
8
π
|
|
π
|
The Human and Mouse Enteric Nervous System at Single-Cell Resolution
17 auth.
Eugene Drokhlyansky,
C. Smillie,
N. V. Wittenberghe,
M. Ericsson,
G. Griffin,
Gâkçen Eraslan,
Danielle Dionne,
Michael S. Cuoco,
Max N. Goder-Reiser,
T. Sharova,
...
Olena Kuksenko,
A. Aguirre,
G. Boland,
D. Graham,
O. Rozenblatt-Rosen,
R. Xavier,
A. Regev
|
8 |
2020 |
8
π
|
