|
π¦
|
Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
17 auth.
P. Nicklin,
Phil Bergman,
Bailin Zhang,
E. Triantafellow,
Henry Wang,
B. Nyfeler,
Haidi Yang,
M. Hild,
C. Kung,
Christopher J. Wilson,
...
V. Myer,
J. MacKeigan,
Jeffrey A. Porter,
Y. Karen Wang,
L. Cantley,
P. Finan,
Leon O. Murphy
|
10 |
2009 |
10
π¦
|
|
π
|
Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension
14 auth.
E. Soon,
A. Holmes,
C. Treacy,
N. Doughty,
L. Southgate,
R. Machado,
R. Trembath,
Simon Jennings,
L. Barker,
P. Nicklin,
...
C. Walker,
D. Budd,
J. Pepke-Zaba,
N. Morrell
|
9 |
2010 |
9
π
|
|
π
|
Antisense Research and Application
30 auth.
T. Akiyama,
C. Bennett,
M. Butler,
B. Chiasson,
T. Condon,
S. J. Craig,
R. Crooke,
S. Crooke,
N. Dean,
F. Dorr,
R. Geary,
A. Gewirtz,
M. Hebb,
S. L. Hutcherson,
D. Kisner,
...
A. Krieg,
J. Leeds,
B. Monia,
D. Monteith,
P. Nicklin,
P. Nielsen,
J. Phillips,
H. Robertson,
P. Schechter,
G. Schultz,
W. Shanahan,
M. Templin,
B. Weiss,
B. Wittig,
R. Zhang
|
7 |
1998 |
7
π
|
|
π
|
Inhibition of Growth of Human Tumor Cell Lines in Nude Mice by an Antisense Oligonucleotide Inhibitor of Protein Kinase C-Ξ± Expression
12 auth.
N. Dean,
R. Mckay,
L. Miraglia,
R. Howard,
S. Cooper,
J. Giddings,
...
P. Nicklin,
L. Meister,
R. Ziel,
T. Geiger,
M. MΓΌller,
D. Fabbro
|
7 |
1996 |
7
π
|
|
π
|
Second Generation of Antisense Oligonucleotides: From Nuclease Resistance to Biological Efficacy in Animals
16 auth.
K. Altmann,
N. Dean,
D. Fabbro,
S. Freier,
T. Geiger,
R. HΓ€ner,
D. HΓΌsken,
Pierre Martin,
B. Monia,
M. MΓΌller,
...
F. Natt,
P. Nicklin,
J. Phillips,
U. Pieles,
H. Sasmor,
H. Moser
|
7 |
1996 |
7
π
|
|
π’
|
Pharmacokinetics, metabolism, and elimination of a 20-mer phosphorothioate oligodeoxynucleotide (CGP 69846A) after intravenous and subcutaneous administration.
J. Phillips,
S. Craig,
D. Bayley,
R. Christian,
R. Geary,
P. Nicklin
|
7 |
1997 |
7
π’
|
|
π’
|
Second-generation antisense oligonucleotides: structure-activity relationships and the design of improved signal-transduction inhibitors.
7 auth.
K. Altmann,
D. Fabbro,
N. Dean,
T. Geiger,
B. Monia,
M. MΓΌller,
...
P. Nicklin
|
6 |
1996 |
6
π’
|
|
π¬
|
Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells.
R. V. Giles,
D. Spiller,
J. Grzybowski,
R. Clark,
P. Nicklin,
D. Tidd
|
6 |
1998 |
6
π¬
|
|
π¬
|
Evaluation of Recombinant Cytochrome P450 Enzymes as an in Vitro System for Metabolic Clearance Predictions
R. Stringer,
C. Strain-Damerell,
P. Nicklin,
Brian Houston
|
6 |
2009 |
6
π¬
|
|
π¬
|
Reliability of human cryopreserved hepatocytes and liver microsomes as in vitro systems to predict metabolic clearance
R. Stringer,
P. Nicklin,
J. Houston
|
5 |
2008 |
5
π¬
|
|
π¦
|
Pulmonary Bioavailability of a Phosphorothioate Oligonucleotide (CGP 64128A): Comparison with Other Delivery Routes
7 auth.
P. Nicklin,
D. Bayley,
J. Giddings,
S. J. Craig,
L. Cummins,
J. Hastewell,
...
J. Phillips
|
5 |
1998 |
5
π¦
|
