|
🐜
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Selective inhibition of BET bromodomains
25 auth.
P. Filippakopoulos,
J. Qi,
S. Picaud,
Yao Shen,
William B. Smith,
O. Fedorov,
Elizabeth M. Morse,
T. Keates,
T. Hickman,
I. Felletár,
M. Philpott,
S. Munro,
M. Mckeown,
Yuchuan Wang,
A. Christie,
...
N. West,
M. J. Cameron,
Brian E. Schwartz,
T. Heightman,
N. L. La Thangue,
C. French,
O. Wiest,
A. Kung,
S. Knapp,
J. Bradner
|
11 |
2010 |
11
🐜
|
|
🐢
|
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
13 auth.
P. Filippakopoulos,
S. Picaud,
M. Mangos,
T. Keates,
Jean-Philippe Lambert,
D. Barsyte-Lovejoy,
I. Felletár,
R. Volkmer,
S. Müller,
T. Pawson,
...
A. Gingras,
C. Arrowsmith,
S. Knapp
|
10 |
2012 |
10
🐢
|
|
🐢
|
Targeting bromodomains: epigenetic readers of lysine acetylation
P. Filippakopoulos,
S. Knapp
|
10 |
2014 |
10
🐢
|
|
🐜
|
The promise and peril of chemical probes.
54 auth.
C. Arrowsmith,
J. Audia,
Christopher M. Austin,
J. Baell,
J. Bennett,
J. Blagg,
C. Bountra,
P. Brennan,
P. Brown,
M. Bunnage,
C. Buser-Doepner,
R. Campbell,
Adrian J Carter,
Philip Cohen,
R. Copeland,
...
B. Cravatt,
Jayme L. Dahlin,
D. Dhanak,
A. Edwards,
Mathias Frederiksen,
S. Frye,
N. Gray,
C. Grimshaw,
D. Hepworth,
T. Howe,
K. Huber,
Jian Jin,
S. Knapp,
J. Kotz,
R. Kruger,
D. Lowe,
M. Mader,
B. Marsden,
A. Mueller-Fahrnow,
S. Müller,
R. O'Hagan,
John P. Overington,
D. Owen,
S. Rosenberg,
B. Roth,
R. Ross,
M. Schapira,
S. Schreiber,
B. Shoichet,
M. Sundström,
G. Superti-Furga,
J. Taunton,
L. Toledo-Sherman,
C. Walpole,
M. Walters,
T. Willson,
P. Workman,
R. Young,
W. Zuercher
|
9 |
2015 |
9
🐜
|
|
🐜
|
Protein production and purification
84 auth.
S. Gräslund,
P. Nordlund,
J. Weigelt,
B. Hallberg,
J. Bray,
O. Gileadi,
S. Knapp,
U. Oppermann,
C. Arrowsmith,
R. Hui,
Jinrong Ming,
S. Dhe-Paganon,
Hee-won Park,
A. Savchenko,
A. Yee,
...
A. Edwards,
R. Vincentelli,
C. Cambillau,
R. Kim,
Sung-Hou Kim,
Z. Rao,
Yunyu Shi,
T. Terwilliger,
Chang-Yub Kim,
L. Hung,
G. Waldo,
Y. Peleg,
S. Albeck,
T. Unger,
O. Dym,
J. Prilusky,
J. Sussman,
R. Stevens,
S. Lesley,
I. Wilson,
A. Joachimiak,
F. Collart,
I. Dementieva,
M. Donnelly,
W. Eschenfeldt,
Youngchang Kim,
L. Stols,
Ruying Wu,
Min Zhou,
S. Burley,
J. S. Emtage,
J. M. Sauder,
Devon Thompson,
K. Bain,
J. Luz,
T. Gheyi,
Fred Zhang,
S. Atwell,
S. Almo,
J. Bonanno,
A. Fiser,
S. Swaminathan,
F. Studier,
M. Chance,
A. Sali,
T. Acton,
R. Xiao,
Li Zhao,
Li Chung Ma,
J. Hunt,
L. Tong,
K. Cunningham,
M. Inouye,
S. Anderson,
Heleema Janjua,
R. Shastry,
C. Ho,
Dong-yan Wang,
Huang Wang,
Mei Jiang,
G. Montelione,
D. Stuart,
R. Owens,
S. Daenke,
A. Schütz,
U. Heinemann,
S. Yokoyama,
K. Büssow,
K. Gunsalus
|
9 |
2008 |
9
🐜
|
|
🐜
|
The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs
9 auth.
K. Kavanagh,
K. Guo,
J. Dunford,
Xiaoqiu Wu,
S. Knapp,
F. H. Ebetino,
...
M. Rogers,
R. Russell,
U. Oppermann
|
9 |
2006 |
9
🐜
|
|
🐜
|
Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases*
9 auth.
C. Filling,
K. Berndt,
J. Benach,
S. Knapp,
T. Prozorovski,
E. Nordling,
...
R. Ladenstein,
H. Jörnvall,
U. Oppermann
|
9 |
2002 |
9
🐜
|
|
🐢
|
Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome
10 auth.
A. Barr,
E. Ugochukwu,
W. H. Lee,
Oliver N. F. King,
P. Filippakopoulos,
I. Alfano,
...
P. Savitsky,
N. Burgess-Brown,
S. Müller,
S. Knapp
|
8 |
2009 |
8
🐢
|
|
🐜
|
Linear Motif Atlas for Phosphorylation-Dependent Signaling
23 auth.
Martin L. Miller,
L. Jensen,
F. Diella,
C. Jørgensen,
M. Tinti,
Lei Li,
Marilyn S. Hsiung,
Sirlester A. Parker,
J. Bordeaux,
Thomas Sicheritz-Pontén,
...
Marina Olhovsky,
A. Pasculescu,
Jess Alexander,
S. Knapp,
Nikolaj S. Blom,
P. Bork,
S. Li,
G. Cesareni,
T. Pawson,
B. Turk,
M. Yaffe,
S. Brunak,
R. Linding
|
8 |
2008 |
8
🐜
|
|
🐬
|
Trends in kinase drug discovery: targets, indications and inhibitor design
Misty M. Attwood,
D. Fabbro,
Aleksandr V Sokolov,
S. Knapp,
H. Schiöth
|
8 |
2021 |
8
🐬
|
|
🐜
|
A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon
9 auth.
L. Gurtler,
Peter H. Hauser,
Josef Eberle,
'. Albrecht,
V. Brunn,
S. Knapp,
...
L. Zekeng,
J. Tsague,
L. Kaptue
|
8 |
1994 |
8
🐜
|
|
🐜
|
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain
15 auth.
S. Picaud,
C. Wells,
I. Felletár,
D. Brotherton,
Sarah Martin,
P. Savitsky,
Beatriz Díez-Dacal,
M. Philpott,
C. Bountra,
Hannah Lingard,
...
O. Fedorov,
S. Müller,
P. Brennan,
S. Knapp,
P. Filippakopoulos
|
8 |
2013 |
8
🐜
|
|
🐢
|
Bromodomains as therapeutic targets
S. Muller,
P. Filippakopoulos,
S. Knapp
|
8 |
2011 |
8
🐢
|
