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Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
31 auth.
S. Fanning,
Aftabul Haque,
Thibaut Imberdis,
Valeriya Baru,
M. I. Barrasa,
S. Nuber,
D. Termine,
N. Ramalingam,
Gary P. H. Ho,
T. Noble,
Jackson Sandoe,
Yali Lou,
D. Landgraf,
Y. Freyzon,
Gregory A. Newby,
...
F. Soldner,
Elizabeth Terry-Kantor,
Tae-Eun Kim,
Harald F. Hofbauer,
Michel Becuwe,
R. Jaenisch,
David Pincus,
C. Clish,
T. Walther,
Robert V Farese,
S. Srinivasan,
M. Welte,
S. Kohlwein,
Ulf Dettmer,
S. Lindquist,
D. Selkoe
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7 |
2018 |
7 🐜
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Loss of native &agr;-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells
13 auth.
Ulf Dettmer,
N. Ramalingam,
Victoria E. von Saucken,
Tae-Eun Kim,
A. Newman,
Elizabeth Terry-Kantor,
S. Nuber,
M. Ericsson,
S. Fanning,
Tim Bartels,
...
S. Lindquist,
O. Levy,
D. Selkoe
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6 |
2017 |
6 🐜
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Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase
12 auth.
Thibaut Imberdis,
Joseph M. Negri,
N. Ramalingam,
Elizabeth Terry-Kantor,
Gary P. H. Ho,
S. Fanning,
...
Georgia L. Stirtz,
Tae-Eun Kim,
O. Levy,
T. Young-Pearse,
D. Selkoe,
Ulf Dettmer
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6 |
2019 |
6 🐜
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🐬
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Dynamic behaviors of α-synuclein and tau in the cellular context: New mechanistic insights and therapeutic opportunities in neurodegeneration
F. Yeboah,
Tae-Eun Kim,
Anke Bill,
Ulf Dettmer
|
4 |
2019 |
4 🐬
|
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Crowded organelles, lipid accumulation, and abnormal membrane tubulation in cellular models of enhanced α-synuclein membrane interaction
7 auth.
M. Ericsson,
Victoria E. von Saucken,
A. Newman,
Lena Doehr,
Camilla Hoesch,
Tae-Eun Kim,
...
Ulf Dettmer
|
3 |
2021 |
3 🐜
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🦁
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Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity
9 auth.
Tae-Eun Kim,
A. Newman,
Thibaut Imberdis,
Lisa Brontesi,
A. Tripathi,
N. Ramalingam,
...
S. Fanning,
D. Selkoe,
Ulf Dettmer
|
3 |
2021 |
3 🦁
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