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Functional Links Between Aฮฒ Toxicity, Endocytic Trafficking, and Alzheimerโs Disease Risk Factors in Yeast
21 auth.
S. Treusch,
S. Hamamichi,
J. L. Goodman,
K. Matlack,
C. Chung,
Valeriya Baru,
J. Shulman,
A. Parrado,
B. Bevis,
Julie S. Valastyan,
...
Haesun Han,
M. Lindhagen-Persson,
E. Reiman,
Denis A. Evans,
D. Bennett,
A. Olofsson,
P. Dejager,
R. Tanzi,
Kim A. Caldwell,
G. Caldwell,
S. Lindquist
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8 |
2011 |
8
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Identification and Rescue of -Synuclein Toxicity in Parkinson Patient-Derived Neurons
22 auth.
C. Chung,
V. Khurana,
P. Auluck,
D. Tardiff,
Joseph R. Mazzulli,
F. Soldner,
Valeriya Baru,
Yali Lou,
Y. Freyzon,
Sukhee Cho,
...
A. Mungenast,
J. Muffat,
M. Mitalipova,
Michael D. Pluth,
N. Jui,
B. Schรผle,
S. Lippard,
L. Tsai,
D. Krainc,
S. Buchwald,
R. Jaenisch,
S. Lindquist
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8 |
2013 |
8
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Lipidomic Analysis of ฮฑ-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
31 auth.
S. Fanning,
Aftabul Haque,
Thibaut Imberdis,
Valeriya Baru,
M. I. Barrasa,
S. Nuber,
D. Termine,
N. Ramalingam,
Gary P. H. Ho,
T. Noble,
Jackson Sandoe,
Yali Lou,
D. Landgraf,
Y. Freyzon,
Gregory A. Newby,
...
F. Soldner,
Elizabeth Terry-Kantor,
Tae-Eun Kim,
Harald F. Hofbauer,
Michel Becuwe,
R. Jaenisch,
David Pincus,
C. Clish,
T. Walther,
Robert V Farese,
S. Srinivasan,
M. Welte,
S. Kohlwein,
Ulf Dettmer,
S. Lindquist,
D. Selkoe
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7 |
2018 |
7
๐
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๐
|
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia
18 auth.
Grzegorz Sienski,
Priyanka Narayan,
J. M. Bonner,
Nora Kory,
Sebastian Boland,
A. Arczewska,
William T. Ralvenius,
L. Akay,
Elana Lockshin,
Liang He,
...
Blerta Milo,
Agnese Graziosi,
Valeriya Baru,
C. Lewis,
Manolis Kellis,
D. Sabatini,
L. Tsai,
S. Lindquist
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7 |
2021 |
7
๐
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Identification and Rescue of ฮฑ-Synuclein Toxicity in Parkinson PatientโDerived Neurons
22 auth.
C. Chung,
V. Khurana,
P. Auluck,
D. Tardiff,
Joseph R. Mazzulli,
F. Soldner,
Valeriya Baru,
Yali Lou,
Y. Freyzon,
Sukhee Cho,
...
A. Mungenast,
J. Muffat,
M. Mitalipova,
Michael D. Pluth,
N. Jui,
Birgitt Schรผle,
S. Lippard,
Li-Huei Tsai,
D. Krainc,
S. Buchwald,
R. Jaenisch,
Susan Lindquist
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7 |
2013 |
7
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๐
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Genome-Scale Networks Link Neurodegenerative Disease Genes to ฮฑ-Synuclein through Specific Molecular Pathways.
33 auth.
V. Khurana,
V. Khurana,
V. Khurana,
Jian Peng,
C. Chung,
P. Auluck,
S. Fanning,
D. Tardiff,
Theresa Bartels,
M. Koeva,
Stephen W. Eichhorn,
H. Benyamini,
Yali Lou,
Andy Nutter-Upham,
Valeriya Baru,
...
Y. Freyzon,
Nurcan Tuncbag,
M. Costanzo,
Bryan-Joseph San Luis,
David C. Schรถndorf,
M. I. Barrasa,
Sepehr Ehsani,
Neville E. Sanjana,
Neville E. Sanjana,
Q. Zhong,
T. Gasser,
D. Bartel,
M. Vidal,
M. Deleidi,
Charles Boone,
E. Fraenkel,
B. Berger,
S. Lindquist
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6 |
2017 |
6
๐
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|
๐
|
Calcineurin determines toxic versus beneficial responses to ฮฑ-synuclein
16 auth.
G. Caraveo,
P. Auluck,
L. Whitesell,
C. Chung,
Valeriya Baru,
E. Mosharov,
Xiaohui Yan,
Manu Ben-Johny,
Martin Soste,
P. Picotti,
...
H. Kim,
Kim A. Caldwell,
G. Caldwell,
D. Sulzer,
D. T. Yue,
S. Lindquist
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6 |
2014 |
6
๐
|
|
๐
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In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.
14 auth.
C. Chung,
V. Khurana,
S. Yi,
Nidhi Sahni,
Ken H. Loh,
P. Auluck,
Valeriya Baru,
N. Udeshi,
Y. Freyzon,
S. Carr,
...
D. Hill,
M. Vidal,
A. Ting,
S. Lindquist
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6 |
2017 |
6
๐
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PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.
22 auth.
Priyanka Narayan,
Priyanka Narayan,
Priyanka Narayan,
Grzegorz Sienski,
J. M. Bonner,
J. M. Bonner,
Yuan-Ta Lin,
Jinsoo Seo,
Valeriya Baru,
Aftabul Haque,
...
Blerta Milo,
L. Akay,
Agnese Graziosi,
Y. Freyzon,
D. Landgraf,
W. R. Hesse,
Julie S. Valastyan,
M. I. Barrasa,
Li-Huei Tsai,
Li-Huei Tsai,
Susan Lindquist,
Susan Lindquist
|
5 |
2020 |
5
๐
|
|
๐
|
Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls
13 auth.
Dina Simkin,
Vasileios Papakis,
B. Bustos,
Christina Ambrosi,
S. J. Ryan,
Valeriya Baru,
Luis A. Williams,
Graham T Dempsey,
O. McManus,
J. Landers,
...
S. Lubbe,
Alfred L. George,
E. Kiskinis
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5 |
2022 |
5
๐
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