|
🐜
|
TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts
38 auth.
Angelo L Grauel,
Beverly Nguyen,
D. Ruddy,
Tyler Laszewski,
S. Schwartz,
Jonathan Chang,
Julie T. Chen,
M. Piquet,
M. Pelletier,
Zheng Yan,
N. Kirkpatrick,
Jincheng Wu,
Antoine deWeck,
Markus Riester,
Matthew M. Hims,
...
F. Geyer,
Joel Wagner,
K. MacIsaac,
J. Deeds,
Rohan Diwanji,
Pushpa Jayaraman,
Yenyen Yu,
Quincey Simmons,
Shaobu Weng,
Alina Raza,
Brian Minie,
Mirek Dostalek,
Pavitra Chikkegowda,
V. Ruda,
O. Iartchouk,
Naiyan Chen,
Raphaël Thierry,
Joseph Zhou,
Iulian Pruteanu-Malinici,
C. Fabre,
J. Engelman,
G. Dranoff,
V. Cremasco
|
6 |
2020 |
6
🐜
|
|
🐜
|
Therapeutic assessment of targeting ASNS combined with L-Asparaginase treatment in solid tumors and investigation of resistance mechanisms
17 auth.
Verena Apfel,
D. Begue,
Valentina Cordo’,
Laura Holzer,
Laetitia Martinuzzi,
Alexandra Buhles,
G. Kerr,
Inês A M Barbosa,
U. Naumann,
M. Piquet,
...
D. Ruddy,
A. Weiss,
S. Ferretti,
Reinaldo Almeida,
D. Bonenfant,
L. Tordella,
G. Galli
|
4 |
2020 |
4
🐜
|
|
🐜
|
CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non–Small Cell Lung Cancer
22 auth.
A. Prahallad,
Andreas Weiss,
Hans Voshol,
G. Kerr,
K. Sprouffske,
Tina Yuan,
D. Ruddy,
Morgane Meistertzheim,
Malika Kazic-Legueux,
Tina Kottarathil,
...
M. Piquet,
Yichen Cao,
Laetitia Martinuzzi-Duboc,
Alexandra Buhles,
Flavia Alder,
Salvatore Mannino,
L. Tordella,
Laurent Sansregret,
S. Maira,
Diana Graus Porta,
Carmine Fedele,
S. Brachmann
|
3 |
2023 |
3
🐜
|
|
🐜
|
Targeting the IL-1β pathway for cancer immunotherapy remodels the tumor microenvironment and enhances antitumor immune responses.
24 auth.
Rohan Diwanji,
Neil A. O’Brien,
Jiyoung E Choi,
Beverly Nguyen,
Tyler Laszewski,
Angelo L Grauel,
Zheng Yan,
Xin Xu,
Jincheng Wu,
D. Ruddy,
...
M. Piquet,
M. Pelletier,
A. Savchenko,
LaSalette Charette,
V. Rodrik-Outmezguine,
J. Baum,
J. Millholland,
Connie C Wong,
Anne-Marie Martin,
G. Dranoff,
Iulian Pruteanu-Malinici,
V. Cremasco,
Catherine Sabatos-Peyron,
Pushpa Jayaraman
|
2 |
2023 |
2
🐜
|
|
🐜
|
INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas
22 auth.
Ahmed M. O. Elbatsh,
Ali Amin-Mansour,
Anne Haberkorn,
Claudia Textor,
N. Ebel,
Emilie Renard,
Lisa M Koch,
Femke C Groenveld,
M. Piquet,
Ulrike Naumann,
...
D. Ruddy,
Vincent Romanet,
J. M. Martínez Gómez,
M. Shirley,
P. Wipfli,
Christian Schnell,
Markus Wartmann,
Martin Rausch,
Martine J. Jager,
Mitchell P. Levesque,
S. Maira,
Eusebio Manchado
|
2 |
2024 |
2
🐜
|
|
🐜
|
CRISPR screening identifies T cell-intrinsic regulators of CD3-bispecific antibody responses
13 auth.
Ryan D. Molony,
T. Funk,
Gina M. Trabucco,
Erik Corcoran,
D. Ruddy,
Malini Varadarajan,
GiNell Elliot,
M. Piquet,
Joni W. Lam,
M. Meyer,
...
H. Wang,
S. Kurtuluş,
Haihui Lu
|
2 |
2022 |
2
🐜
|
|
🐜
|
Dysfunction of infiltrating cytotoxic CD8+ T cells within the graft promotes murine kidney allotransplant tolerance
14 auth.
Takahiro Yokose,
Edward S. Szuter,
Ivy Rosales,
Michael T Guinn,
Andrew S. Liss,
Taisuke Baba,
David A Ruddy,
M. Piquet,
Jamil Azzi,
A. Cosimi,
...
Paul S Russell,
J. Madsen,
Robert B. Colvin,
Alessandro Alessandrini
|
1 |
2024 |
1
🐜
|
