|
๐
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APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline
27 auth.
Axel Montagne,
D. Nation,
A. Sagare,
G. Barisano,
Melanie D. Sweeney,
A. Chakhoyan,
M. Pachicano,
Elizabeth Joe,
Amy R. Nelson,
Lina M. DโOrazio,
David P. Buennagel,
M. Harrington,
T. Benzinger,
A. Fagan,
J. Ringman,
...
L. Schneider,
J. Morris,
E. Reiman,
R. Caselli,
H. Chui,
J. Tcw,
Yining Chen,
J. Pa,
P. Conti,
Meng Law,
A. Toga,
B. Zlokovic
|
9 |
2020 |
9
๐
|
|
๐
|
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
28 auth.
Miao Xu,
Emily M. Lee,
Z. Wen,
Yichen Cheng,
Wei-Kai Huang,
Xuyu Qian,
J. Tcw,
Jennifer Kouznetsova,
Sarah C. Ogden,
Christy Hammack,
Fadi Jacob,
H. N. Nguyen,
Misha Itkin,
C. Hanna,
P. Shinn,
...
Chase A. Allen,
Sam Michael,
A. Simeonov,
Wenwei Huang,
K. Christian,
A. Goate,
K. Brennand,
Ruili Huang,
M. Xia,
G. Ming,
Wei Zheng,
Hongjun Song,
Hengli Tang
|
9 |
2016 |
9
๐
|
|
๐ฆ
|
An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
14 auth.
J. Tcw,
Minghui Wang,
A. A. Pimenova,
Kathryn R Bowles,
B. Hartley,
Emre Lacin,
S. Machlovi,
Rawan Abdelaal,
C. Karch,
H. Phatnani,
...
P. Slesinger,
Bin Zhang,
A. Goate,
K. Brennand
|
8 |
2017 |
8
๐ฆ
|
|
๐
|
Innate immunity protein IFITM3 modulates ฮณ-secretase in Alzheimer disease
31 auth.
J. Hur,
Georgia Frost,
Xianzhong Wu,
Christina J. Crump,
S. Pan,
Eitan Wong,
Marilia Barros,
Thomas Li,
Pengju Nie,
Y. Zhai,
Jen C. Wang,
J. Tcw,
Lei Guo,
A. McKenzie,
Chen Ming,
...
Xianxiao Zhou,
Minghui Wang,
Y. Sagi,
A. Renton,
Bianca T Esposito,
Yong Kim,
Katherine R. Sadleir,
I. Trinh,
R. Rissman,
R. Vassar,
Bin Zhang,
Douglas S. Johnson,
E. Masliah,
P. Greengard,
A. Goate,
Yue-Ming Li
|
7 |
2020 |
7
๐
|
|
๐
|
Molecular subtyping of Alzheimerโs disease using RNA sequencing data reveals novel mechanisms and targets
24 auth.
Ryan A. Neff,
Minghui Wang,
Sezen Vatansever,
Lei Guo,
Chen Ming,
Qian Wang,
E. Wang,
Emrin HorgusluogluโMoloch,
Won-min Song,
Aiqun Li,
...
Emilie L. Castranio,
J. Tcw,
L. Ho,
A. Goate,
V. Fossati,
S. Noggle,
S. Gandy,
M. Ehrlich,
P. Katsel,
E. Schadt,
Dongming Cai,
K. Brennand,
V. Haroutunian,
Bin Zhang
|
7 |
2021 |
7
๐
|
|
๐ฆ
|
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
21 auth.
J. Tcw,
L. Qian,
N. Pipalia,
M. Chao,
Shuang A. Liang,
Yang Shi,
Bharat R. Jain,
S. Bertelsen,
Manav Kapoor,
Edoardo Marcora,
...
Elizabeth Sikora,
Elizabeth J. Andrews,
A. Martini,
C. Karch,
E. Head,
D. Holtzman,
Bin Zhang,
Minghui Wang,
F. Maxfield,
W. Poon,
A. Goate
|
7 |
2022 |
7
๐ฆ
|
|
๐
|
Integration of Alzheimerโs disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
17 auth.
Gloriia Novikova,
Manav Kapoor,
J. Tcw,
Edsel Abud,
Anastasia G. Efthymiou,
S. Chen,
Haoxiang Cheng,
J. Fullard,
J. Bendl,
Yiyuan Liu,
...
P. Roussos,
J. Bjรถrkegren,
Yunlong Liu,
W. Poon,
K. Hao,
Edoardo Marcora,
A. Goate
|
7 |
2021 |
7
๐
|
|
๐ฆ
|
Genetics of ฮฒ-Amyloid Precursor Protein in Alzheimer's Disease.
J. Tcw,
A. Goate
|
7 |
2017 |
7
๐ฆ
|
|
๐
|
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.
7 auth.
Seok-Man Ho,
B. Hartley,
J. Tcw,
M. Beaumont,
Khalifa Stafford,
P. Slesinger,
...
K. Brennand
|
7 |
2016 |
7
๐
|
|
๐ฌ
|
Genetic architecture of Alzheimer's disease
Sarah M. Neuner,
J. Tcw,
A. Goate
|
6 |
2020 |
6
๐ฌ
|
|
๐
|
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
20 auth.
K. Leng,
Indigo V. L. Rose,
Hyosung Kim,
Wenlong Xia,
W. Romero-Fernandez,
B. Rooney,
Mark Koontz,
E. Li,
Y. Ao,
Shinong Wang,
...
Mitchell C Krawczyk,
J. Tcw,
Alison A Goate,
Ye Zhang,
E. Ullian,
M. Sofroniew,
S. Fancy,
M. Schrag,
E. Lippmann,
M. Kampmann
|
6 |
2022 |
6
๐
|
