🐜
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A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385*
9 auth.
S. Rowlinson,
J. Kiefer,
J. Prusakiewicz,
J. Pawlitz,
K. Kozak,
A. Kalgutkar,
...
W. Stallings,
R. Kurumbail,
L. Marnett
|
8 |
2003 |
8 🐜
|
🐜
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The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: the second clinical candidate having a shorter and favorable human half-life.
12 auth.
Jane L. Wang,
David C. Limburg,
M. Graneto,
J. Springer,
Joseph Rogier Bruce Hamper,
S. Liao,
...
J. Pawlitz,
R. Kurumbail,
T. Maziasz,
J. Talley,
J. Kiefer,
J. Carter
|
8 |
2010 |
8 🐜
|
🐜
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Structural insights into the stereochemistry of the cyclooxygenase reaction
12 auth.
J. Kiefer,
J. Pawlitz,
K. Moreland,
R. Stegeman,
W. Hood,
J. Gierse,
...
A. Stevens,
D. Goodwin,
S. Rowlinson,
L. Marnett,
W. Stallings,
R. Kurumbail
|
7 |
2000 |
7 🐜
|
🐜
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Synthesis, crystal structure, and activity of pyrazole-based inhibitors of p38 kinase.
20 auth.
M. Graneto,
R. Kurumbail,
M. Vazquez,
H. Shieh,
J. Pawlitz,
Jennifer M. Williams,
W. Stallings,
L. Geng,
Ashok S Naraian,
F. Koszyk,
...
M. A. Stealey,
Xiangdong Xu,
R. Weier,
G. Hanson,
R. Mourey,
R. Compton,
S. Mnich,
G. Anderson,
J. Monahan,
R. Devraj
|
5 |
2007 |
5 🐜
|
🐜
|
The novel benzopyran class of selective cyclooxygenase-2 inhibitors-part I: the first clinical candidate.
10 auth.
Jane L. Wang,
J. Carter,
J. Kiefer,
R. Kurumbail,
J. Pawlitz,
David Brown,
...
S. Hartmann,
M. Graneto,
K. Seibert,
J. Talley
|
5 |
2010 |
5 🐜
|
🐜
|
Mechanism of inhibition of novel COX-2 inhibitors.
18 auth.
J. Gierse,
R. Kurumbail,
M. Walker,
Bill Hood,
J. Monahan,
J. Pawlitz,
R. Stegeman,
A. Stevens,
J. Kiefer,
C. Koboldt,
...
K. Moreland,
S. Rowlinson,
L. Marnett,
Jennifer L. Pierce,
J. Carter,
J. Talley,
P. Isakson,
K. Seibert
|
2 |
2002 |
2 🐜
|
🐜
|
Crystallization of recombinant cyclo-oxygenase-2
8 auth.
A. Stevens,
J. Pawlitz,
R. Kurumbail,
J. Gierse,
K. Moreland,
R. Stegeman,
...
J. LoDuca,
W. Stallings
|
2 |
1999 |
2 🐜
|
🐜
|
CRYSTAL STRUCTURE OF DICLOFENAC BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2
9 auth.
J. Kiefer,
S. Rowlinson,
J. Prusakiewicz,
J. Pawlitz,
K. Kozak,
A. Kalgutkar,
...
W. Stallings,
L. Marnett,
R. Kurumbail
|
1 |
2003 |
1 🐜
|
🐜
|
CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2
11 auth.
J. Kiefer,
J. Pawlitz,
K. Moreland,
R. Stegeman,
J. Gierse,
A. Stevens,
...
D. Goodwin,
S. Rowlinson,
L. Marnett,
W. Stallings,
R. Kurumbail
|
0 |
2000 |
0 🐜
|