|
🦁
|
Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist.
10 auth.
M. Clozel,
V. Breu,
G. Gray,
B. Kalina,
B. Löffler,
K. Burri,
...
J. Cassal,
G. Hirth,
Marcel Muller,
Werner L. Neidhart
|
9 |
1994 |
9
🦁
|
|
🐜
|
Promotion of sleep by targeting the orexin system in rats, dogs and humans
18 auth.
C. Brisbare-Roch,
J. Dingemanse,
R. Koberstein,
P. Hoever,
H. Aissaoui,
S. Flores,
Célia Mueller,
O. Nayler,
J. Gerven,
S. Haas,
...
P. Hess,
C. Qiu,
Stephan Buchmann,
M. Scherz,
T. Weller,
W. Fischli,
M. Clozel,
F. Jenck
|
9 |
2007 |
9
🐜
|
|
🦁
|
Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist
11 auth.
M. Clozel,
V. Breu,
K. Burri,
J. Cassal,
W. Fischli,
G. Gray,
...
G. Hirth,
Bernd-Michael Löffier,
Marcel Müller,
Werner L. Neidhart,
H. Ramuz
|
8 |
1993 |
8
🦁
|
|
🐢
|
Pharmacology of Macitentan, an Orally Active Tissue-Targeting Dual Endothelin Receptor Antagonist
14 auth.
M. Iglarz,
C. Binkert,
K. Morrison,
W. Fischli,
J. Gatfield,
A. Treiber,
T. Weller,
M. Bolli,
C. Boss,
Stephan Buchmann,
...
Bruno Capeleto,
P. Hess,
C. Qiu,
M. Clozel
|
8 |
2008 |
8
🐢
|
|
🐜
|
A Causative Role for Redox Cycling of Myoglobin and Its Inhibition by Alkalinization in the Pathogenesis and Treatment of Rhabdomyolysis-induced Renal Failure*
14 auth.
K. Moore,
S. Holt,
R. Patel,
D. Svistunenko,
W. Zackert,
D. Goodier,
B. Reeder,
M. Clozel,
R. Anand,
C. Cooper,
...
J. Morrow,
Michael T. Wilson,
V. Darley-Usmar,
L. Roberts
|
8 |
1998 |
8
🐜
|
|
🦁
|
Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats.
M. Clozel,
H. Kuhn,
F. Hefti
|
7 |
1990 |
7
🦁
|
|
🐬
|
Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan).
J. Teerlink,
B. Löffler,
P. Hess,
J. Maire,
M. Clozel,
J. Clozel
|
7 |
1994 |
7
🐬
|
|
🦁
|
BQ-123, a peptidic endothelin ETA receptor antagonist, prevents the early cerebral vasospasm following subarachnoid hemorrhage after intracisternal but not intravenous injection.
M. Clozel,
H. Watanabe
|
7 |
1993 |
7
🦁
|
|
🐬
|
Slow Receptor Dissociation Kinetics Differentiate Macitentan from Other Endothelin Receptor Antagonists in Pulmonary Arterial Smooth Muscle Cells
J. Gatfield,
Celia Mueller Grandjean,
T. Sasse,
M. Clozel,
O. Nayler
|
7 |
2012 |
7
🐬
|
|
🐜
|
Up-regulation of endothelin-B receptors in atherosclerotic human coronary arteries.
8 auth.
Patrick H. Dagassan,
V. Breu,
M. Clozel,
A. Künzli,
P. Vogt,
M. Turina,
...
W. Kiowski,
J. Clozel
|
7 |
1996 |
7
🐜
|
|
🦁
|
Effect of Angiotensin Converting Enzyme Inhibition
M. Clozel,
H. Kuhn,
F. Hefti,
H. Baumgartner
|
7 |
2005 |
7
🦁
|
