๐
|
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
24 auth.
T. Thum,
Carina Gross,
J. Fiedler,
T. Fischer,
S. Kissler,
M. Bussen,
P. Galuppo,
S. Just,
W. Rottbauer,
S. Frantz,
...
M. Castoldi,
J. Soutschek,
V. Koteliansky,
A. Rosenwald,
M. A. Basson,
J. Licht,
John T. G. Pena,
S. Rouhanifard,
M. Muckenthaler,
T. Tuschl,
G. Martin,
J. Bauersachs,
S. Engelhardt,
S. Engelhardt
|
11 |
2008 |
11 ๐
|
๐ฆ
|
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
25 auth.
J. Soutschek,
Akin Akinc,
B. Bramlage,
K. Charissรฉ,
Rainer Constien,
M. Donoghue,
Sayda M. Elbashir,
A. Geick,
P. Hadwiger,
J. Harborth,
Matthias J John,
V. Kesavan,
G. Lavine,
R. Pandey,
T. Racie,
...
K. G. Rajeev,
I. Rรถhl,
I. Toudjarska,
Gang Wang,
Silvio Wuschko,
D. Bumcrot,
V. Koteliansky,
S. Limmer,
M. Manoharan,
H. Vornlocher
|
11 |
2004 |
11 ๐ฆ
|
๐
|
RNAi-mediated gene silencing in non-human primates
29 auth.
Tracy S. Zimmermann,
Amy C. H. Lee,
Akin Akinc,
B. Bramlage,
D. Bumcrot,
M. Fedoruk,
J. Harborth,
J. Heyes,
L. Jeffs,
Matthias J John,
A. Judge,
Kieu Lam,
K. Mcclintock,
L. Nechev,
Lorne Palmer,
...
T. Racie,
I. Rรถhl,
S. Seiffert,
Sumi Shanmugam,
Vandana Sood,
J. Soutschek,
I. Toudjarska,
Amanda J. Wheat,
Ed Yaworski,
William Zedalis,
V. Koteliansky,
M. Manoharan,
H. Vornlocher,
I. Maclachlan
|
10 |
2006 |
10 ๐
|
๐
|
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
33 auth.
Akin Akinc,
A. Zumbuehl,
A. Zumbuehl,
Michael S. Goldberg,
Elizaveta S. Leshchiner,
V. Busini,
Naushad Hossain,
S. Bacallado,
David N. Nguyen,
Jason Fuller,
R. รlvarez,
A. Borodovsky,
T. Borland,
Rainer Constien,
A. D. Fougerolles,
...
J. R. Dorkin,
K. Jayaprakash,
M. Jayaraman,
Matthias J John,
V. Koteliansky,
M. Manoharan,
L. Nechev,
June Qin,
T. Racie,
D. Raitcheva,
K. G. Rajeev,
D. Sah,
J. Soutschek,
I. Toudjarska,
H. Vornlocher,
Tracy S. Zimmermann,
R. Langer,
Dustin Anderson
|
10 |
2008 |
10 ๐
|
๐
|
MicroRNAs 103 and 107 regulate insulin sensitivity
8 auth.
M. Trajkovski,
Jean Hausser,
J. Soutschek,
B. Bhat,
Akinc Akin,
M. Zavolan,
...
M. Heim,
M. Stoffel
|
9 |
2011 |
9 ๐
|
๐
|
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
9 auth.
Li Ma,
Ferenc Reinhardt,
Elizabeth Pan,
J. Soutschek,
B. Bhat,
E. Marcusson,
...
J. Teruya-Feldstein,
G. Bell,
R. Weinberg
|
9 |
2010 |
9 ๐
|
๐
|
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
33 auth.
M. Frank-Kamenetsky,
A. Grefhorst,
Norma N. Anderson,
T. Racie,
B. Bramlage,
Akin Akinc,
David Butler,
K. Charissรฉ,
Robert Dorkin,
Yupeng Fan,
C. GambaโVitalo,
P. Hadwiger,
M. Jayaraman,
Matthias J John,
K. Jayaprakash,
...
Martin E. Maier,
L. Nechev,
K. G. Rajeev,
T. Read,
I. Rรถhl,
J. Soutschek,
P. Tan,
Jamie Wong,
Gang Wang,
Tracy S. Zimmermann,
A. de Fougerolles,
H. Vornlocher,
R. Langer,
Daniel G. Anderson,
M. Manoharan,
V. Koteliansky,
J. Horton,
K. Fitzgerald
|
9 |
2008 |
9 ๐
|
๐
|
A viral microRNA functions as an orthologue of cellular miR-155
11 auth.
E. Gottwein,
N. Mukherjee,
C. Sachse,
C. Frenzel,
William H. Majoros,
J. Chi,
...
Ravi Braich,
M. Manoharan,
J. Soutschek,
U. Ohler,
B. Cullen
|
9 |
2007 |
9 ๐
|
๐
|
miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells.
9 auth.
T. Wรผrdinger,
B. Tannous,
O. Saydam,
J. Skog,
Stephan Grau,
J. Soutschek,
...
R. Weissleder,
X. Breakefield,
Anna M. Krichevsky
|
8 |
2008 |
8 ๐
|
๐
|
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway
16 auth.
Matthias J John,
Rainer Constien,
Akin Akinc,
Michael S. Goldberg,
Y. Moon,
Martina Spranger,
P. Hadwiger,
J. Soutschek,
H. Vornlocher,
M. Manoharan,
...
M. Stoffel,
R. Langer,
Daniel G. Anderson,
J. Horton,
V. Koteliansky,
D. Bumcrot
|
7 |
2007 |
7 ๐
|
๐
|
Mouse Cytomegalovirus MicroRNAs Dominate the Cellular Small RNA Profile during Lytic Infection and Show Features of Posttranscriptional Regulation
10 auth.
L. Dรถlken,
Jonathan Perot,
V. Cognat,
Abdelmalek Alioua,
Matthias J John,
J. Soutschek,
...
Z. Ruzsics,
U. Koszinowski,
O. Voinnet,
S. Pfeffer
|
6 |
2007 |
6 ๐
|
๐ฌ
|
In ovo application of antagomiRs indicates a role for miR-196 in patterning the chick axial skeleton through Hox gene regulation
Edwina McGlinn,
Soraya Yekta,
J. Mansfield,
J. Soutschek,
D. Bartel,
C. Tabin
|
6 |
2009 |
6 ๐ฌ
|
๐ฆ
|
Apoptosis in the cerebellum of adult teleost fish, Apteronotus leptorhynchus.
J. Soutschek,
G. Zupanc
|
6 |
1996 |
6 ๐ฆ
|