|
π
|
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
14 auth.
B. Wienert,
S. Wyman,
Christopher D. Richardson,
Charles D. Yeh,
P. Akçakaya,
M. Porritt,
M. Morlock,
J. Vu,
Katelynn R. Kazane,
Hannah L. Watry,
...
Luke M. Judge,
B. Conklin,
Marcello Maresca,
J. Corn
|
8 |
2018 |
8
π
|
|
π
|
Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells
12 auth.
Jiyung J. Shin,
Markus S. SchrΓΆder,
Francisco Caiado,
S. Wyman,
Nicolas L. Bray,
M. Bordi,
...
M. DeWitt,
J. Vu,
Won-Tae Kim,
D. Hockemeyer,
M. Manz,
J. Corn
|
5 |
2020 |
5
π
|
|
π
|
High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation
20 auth.
W. Magis,
M. DeWitt,
S. Wyman,
J. Vu,
S. Heo,
Shirley J Shao,
F. Hennig,
Z. Romero,
Beatriz Campo-FernaΜndez,
Suzanne Said,
...
Matthew S. McNeill,
G. Rettig,
Yongming Sun,
Yu Wang,
M. Behlke,
D. Kohn,
D. Boffelli,
M. Walters,
J. Corn,
David I. K. Martin
|
5 |
2018 |
5
π
|
|
π
|
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
25 auth.
N. S. Ravi,
B. Wienert,
S. Wyman,
Henry W. Bell,
Anila George,
Gokulnath Mahalingam,
J. Vu,
Kirti Prasad,
Bhanuprasad Bandlamudi,
Nivedhitha Devaraju,
Vignesh Rajendiran,
Nazar Syedbasha,
A. Pai,
Y. Nakamura,
R. Kurita,
...
Muthuraman Narayanasamy,
P. Balasubramanian,
Saravanabhavan Thangavel,
S. Marepally,
S. Velayudhan,
A. Srivastava,
M. DeWitt,
M. Crossley,
J. Corn,
K. M. Mohankumar
|
5 |
2022 |
5
π
|
|
π
|
The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells.
18 auth.
Alan S. Wang,
Leo C. Chen,
R. A. Wu,
R. A. Wu,
Yvonne Hao,
D. McSwiggen,
A. Heckert,
Christopher D. Richardson,
Benjamin G. Gowen,
Katelynn R. Kazane,
...
J. Vu,
S. Wyman,
Jiyung J. Shin,
X. Darzacq,
Johannes C. Walter,
Johannes C. Walter,
Jacob E. Corn,
Jacob E. Corn
|
4 |
2020 |
4
π
|
|
π
|
CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells
12 auth.
Jennifer E. Chung,
W. Magis,
J. Vu,
S. Heo,
K. Wartiovaara,
M. Walters,
...
R. Kurita,
Yukio Nakamura,
D. Boffelli,
D. Martin,
J. Corn,
M. DeWitt
|
4 |
2018 |
4
π
|
|
π
|
In vivo selection for corrected Γ-globin alleles after CRISPR/Cas9 editing in human sickle hematopoietic stem cells enhances therapeutic potential
20 auth.
W. Magis,
M. DeWitt,
S. Wyman,
J. Vu,
S. Heo,
Shirley J Shao,
Fiona Hennig,
Z. Romero,
Beatriz Campo-FernaΜndez,
Matthew S. McNeill,
...
G. Rettig,
Yongming Sun,
Patrick J. Lau,
Yu Wang,
M. Behlke,
D. Kohn,
D. Boffelli,
M. Walters,
J. Corn,
David I. K. Martin
|
4 |
2018 |
4
π
|
|
π¬
|
Antisense targeting of decoy exons can reduce intron retention and increase protein expression in human erythroblasts
M. Parra,
Weiguo Zhang,
J. Vu,
M. DeWitt,
J. Conboy
|
3 |
2020 |
3
π¬
|
