BetterScholar BetterScholar

D. Borchelt

Neuron, Human Molecular Genetics, Cell, Nature Neuroscience, Biomolecular Engineering
13
Role
Title
Level Year L/R
🐜 APP Processing and Synaptic Function
8 auth. Flavio Kamenetz, T. Tomita, Helen Hsieh, G. Seabrook, D. Borchelt, T. Iwatsubo, ... S. Sisodia, R. Malinow 		10 2003
10
🐜
🐜 An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
9 auth. P. Wong, C. Pardo, D. Borchelt, Michael K. Lee, N. Copeland, N. Jenkins, ... S. Sisodia, D. Cleveland, D. Price 		10 1995
10
🐜
🦁 Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate AΞ²1–42/1–40 Ratio In Vitro and In Vivo
20 auth. D. Borchelt, G. Thinakaran, C. Eckman, Michael K. Lee, F. Davenport, T. Ratovitsky, C. Prada, Grace Kim, S. Seekins, D. Yager, ... H. Slunt, Rong Wang, M. Seeger, A. Levey, S. Gandy, N. Copeland, N. Jenkins, D. Price, S. Younkin, S. Sisodia 		10 1996
10
🦁
🐜 ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
11 auth. L. Bruijn, M. Becher, Michael K. Lee, K. Anderson, N. Jenkins, N. Copeland, ... S. Sisodia, J. Rothstein, D. Borchelt, D. Price, D. Cleveland 		10 1997
10
🐜
🐒 Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase
13 auth. J. Jankowsky, J. Jankowsky, Daniel J. Fadale, Jeffrey Anderson, Guilian Xu, V. Gonzales, N. Jenkins, N. Copeland, Michael K. Lee, L. Younkin, ... S. Wagner, S. Younkin, D. Borchelt 		10 2004
10
🐒
🐬 Scrapie prion protein contains a phosphatidylinositol glycolipid
N. Stahl, D. Borchelt, K. Hsiao, S. Prusiner 		10 1987
10
🐬
🐜 Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo
17 auth. G. Thinakaran, D. Borchelt, Michael K. Lee, H. Slunt, L. Spitzer, Grace Kim, T. Ratovitsky, F. Davenport, C. Nordstedt, M. Seeger, ... J. Hardy, A. Levey, S. Gandy, N. Jenkins, N. Copeland, D. Price, S. Sisodia 		10 1996
10
🐜
🦁 Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins
9 auth. D. Borchelt, T. Ratovitski, J. V. Lare, Michael K. Lee, V. Gonzales, N. Jenkins, ... N. Copeland, D. Price, S. Sisodia 		10 1997
10
🦁
🐒 Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
14 auth. Gabriele Schilling, M. Becher, A. Sharp, H. Jinnah, Kui Duan, J. Kotzuk, H. Slunt, T. Ratovitski, J. Cooper, N. Jenkins, ... N. Copeland, D. Price, C. Ross, D. Borchelt 		9 1999
9
🐒
🐜 BACE1 is the major β-secretase for generation of Aβ peptides by neurons
7 auth. H. Cai, Yanshu Wang, D. McCarthy, H. Wen, D. Borchelt, D. Price, ... P. Wong 		9 2001
9
🐜
🐒 Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.
J. Jankowsky, H. Slunt, T. Ratovitski, N. Jenkins, N. Copeland, D. Borchelt 		9 2001
9
🐒
🐒 Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
12 auth. J. Jankowsky, Daniel J. Fadale, Jeffrey Anderson, Guilian Xu, V. Gonzales, N. Jenkins, ... N. Copeland, Michael K. Lee, L. Younkin, S. Wagner, S. Younkin, D. Borchelt 		9 2004
9
🐒
🐜 Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
16 auth. R. Luthi-Carter, A. Strand, N. L. Peters, S. Solano, Z. Hollingsworth, A. S. Menon, A. Frey, Boris S. Spektor, Ellen B. Penney, Gabriele Schilling, ... C. Ross, D. Borchelt, S. Tapscott, A. Young, J. Cha, James M. Olson 		9 2000
9
🐜