|
π
|
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1.
12 auth.
A. Iwama,
H. Oguro,
M. Negishi,
Y. Kato,
Y. Morita,
H. Tsukui,
...
H. Ema,
T. Kamijo,
Y. Katoh-Fukui,
H. Koseki,
M. van Lohuizen,
H. Nakauchi
|
9 |
2004 |
9
π
|
|
π
|
Essential and Instructive Roles of GATA Factors in Eosinophil Development
13 auth.
Ryutaro Hirasawa,
R. Shimizu,
Satoru Takahashi,
M. Osawa,
Shuta Takayanagi,
Y. Kato,
M. Onodera,
N. Minegishi,
Masayuki Yamamoto,
K. Fukao,
...
H. Taniguchi,
H. Nakauchi,
A. Iwama
|
7 |
2002 |
7
π
|
|
π¦
|
Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis
10 auth.
Y. Kato,
A. Iwama,
Y. Tadokoro,
K. Shimoda,
Mayu Minoguchi,
S. Akira,
...
Minoru Tanaka,
A. Miyajima,
T. Kitamura,
H. Nakauchi
|
7 |
2005 |
7
π¦
|
|
π
|
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.
19 auth.
Wenbin Xiao,
H. Hong,
Y. Kawakami,
Y. Kato,
Dianqing Wu,
Hiroki Yasudo,
A. Kimura,
H. Kubagawa,
L. Bertoli,
R. Davis,
...
L. Chau,
J. Madrenas,
C. Hsia,
A. Xenocostas,
T. Kipps,
L. Hennighausen,
A. Iwama,
H. Nakauchi,
T. Kawakami
|
6 |
2009 |
6
π
|
|
π
|
The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells
18 auth.
Yuki Nishida,
A. Maeda,
M. Kim,
L. Cao,
Yasushi Kubota,
J. Ishizawa,
A. Alrawi,
Y. Kato,
Atsushi Iwama,
M. Fujisawa,
...
Kosei Matsue,
M. Weetall,
M. Dumble,
Michael Andreeff,
Thomas W. Davis,
A. Branstrom,
Shinya Kimura,
K. Kojima
|
6 |
2017 |
6
π
|
|
π
|
Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes.
19 auth.
S. Koide,
M. Oshima,
K. Takubo,
S. Yamazaki,
E. Nitta,
A. Saraya,
Kazumasa Aoyama,
Y. Kato,
S. Miyagi,
Yaeko Nakajima-Takagi,
...
T. Chiba,
H. Matsui,
F. Arai,
Yutaka Suzuki,
H. Kimura,
H. Nakauchi,
T. Suda,
Y. Shinkai,
A. Iwama
|
6 |
2016 |
6
π
|
|
π
|
Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition
15 auth.
Ola Rizq,
N. Mimura,
M. Oshima,
A. Saraya,
S. Koide,
Y. Kato,
Kazumasa Aoyama,
Yaeko Nakajima-Takagi,
Changshan Wang,
T. Chiba,
...
Anqi Ma,
Jian Jin,
T. Iseki,
C. Nakaseko,
A. Iwama
|
5 |
2017 |
5
π
|
|
π¬
|
Epigenetic Regulation of Hematopoietic Stem Cell Self-Renewal by Polycomb Group Genes
A. Iwama,
H. Oguro,
M. Negishi,
Y. Kato,
H. Nakauchi
|
5 |
2005 |
5
π¬
|
|
π
|
The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells.
15 auth.
S. Miyagi,
P. SroczyΕska,
Y. Kato,
Yaeko Nakajima-Takagi,
M. Oshima,
Ola Rizq,
N. Takayama,
A. Saraya,
S. Mizuno,
F. Sugiyama,
...
Satoru Takahashi,
Y. Matsuzaki,
J. Christensen,
K. Helin,
A. Iwama
|
5 |
2019 |
5
π
|
|
π
|
Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome
12 auth.
Kazumasa Aoyama,
M. Oshima,
S. Koide,
Emi Suzuki,
Makiko Mochizuki-Kashio,
Y. Kato,
...
Shiro Tara,
Daisuke Shinoda,
Nobuhiro Hiura,
Yaeko Nakajima-Takagi,
G. Sashida,
A. Iwama
|
4 |
2018 |
4
π
|
