🐜
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Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models
12 auth.
P. Haselmayer,
M. Camps,
L. Liu-Bujalski,
Ngan Nguyen,
F. Morandi,
J. Head,
...
A. O’Mahony,
S. Zimmerli,
L. Bruns,
Andrew T. Bender,
P. Schroeder,
R. Grenningloh
|
6 |
2019 |
6 🐜
|
🐜
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Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells
8 auth.
U. Baschant,
L. Frappart,
U. Rauchhaus,
L. Bruns,
H. Reichardt,
T. Kamradt,
...
R. Bräuer,
J. Tuckermann
|
6 |
2011 |
6 🐜
|
🐜
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Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis
8 auth.
O. Frey,
J. Meisel,
A. Hutloff,
K. Bonhagen,
L. Bruns,
R. Kroczek,
...
L. Morawietz,
T. Kamradt
|
6 |
2010 |
6 🐜
|
🦁
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Immunization with an immunodominant self-peptide derived from glucose-6-phosphate isomerase induces arthritis in DBA/1 mice
L. Bruns,
O. Frey,
L. Morawietz,
C. Landgraf,
R. Volkmer,
T. Kamradt
|
4 |
2009 |
4 🦁
|
🐜
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Characterization of Novel PI3Kδ Inhibitors as Potential Therapeutics for SLE and Lupus Nephritis in Pre-Clinical Studies
20 auth.
P. Haselmayer,
M. Camps,
Mathilde Muzerelle,
S. el Bawab,
C. Waltzinger,
L. Bruns,
Nada Abla,
M. Polokoff,
Carole Jond-Necand,
Marilène Gaudet,
...
Audrey Benoit,
Dominique Bertschy Meier,
Catherine P Martin,
D. Gretener,
M. S. Lombardi,
R. Grenningloh,
C. Ladel,
J. Petersen,
P. Gaillard,
H. Ji
|
4 |
2014 |
4 🐜
|
🐬
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B Cell Depletion Reduces the Number of Autoreactive T Helper Cells and Prevents Glucose-6-Phosphate Isomerase-Induced Arthritis
O. Frey,
L. Bruns,
L. Morawietz,
K. Dunussi-joannopoulos,
T. Kamradt
|
3 |
2011 |
3 🐬
|
🐜
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THU0275 Pharmacodynamic Modeling of BTK Occupancy versus Efficacy in RA and SLE Models Using The Novel Specific BTK Inhibitor M2951
10 auth.
P. Haselmayer,
M. Camps,
L. Liu-Bujalski,
F. Morandi,
J. Head,
S. Zimmerli,
...
L. Bruns,
A. Bender,
P. Schroeder,
R. Grenningloh
|
1 |
2016 |
1 🐜
|
🐬
|
Short‐term depletion of regulatory T cells converts self‐limiting arthritis into a chronic disease
T. Kamradt,
L. Bruns,
O. Frey,
A. Reichel,
L. Morawietz
|
0 |
2008 |
0 🐬
|