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🐜
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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
115 auth.
L. Wain,
L. Wain,
N. Shrine,
M. Artigas,
A. Erzurumluoglu,
B. Noyvert,
L. Bossini‐Castillo,
M. Obeidat,
A. Henry,
M. Portelli,
R. Hall,
C. Billington,
T. Rimington,
A. Fenech,
C. John,
...
T. Blake,
V. Jackson,
R. Allen,
B. Prins,
A. Campbell,
D. Porteous,
M. Järvelin,
M. Järvelin,
M. Wielscher,
A. James,
J. Hui,
N. Wareham,
J. Zhao,
James F. Wilson,
Peter K. Joshi,
B. Stubbe,
R. Rawal,
H. Schulz,
M. Imboden,
N. Probst-Hensch,
S. Karrasch,
C. Gieger,
I. Deary,
S. Harris,
J. Marten,
I. Rudan,
Stefan Enroth,
U. Gyllensten,
S. Kerr,
O. Polašek,
O. Polašek,
M. Kähönen,
I. Surakka,
I. Surakka,
V. Vitart,
C. Hayward,
T. Lehtimäki,
O. Raitakari,
David M. Evans,
A. J. Henderson,
C. Pennell,
Carol A. Wang,
P. Sly,
E. Wan,
R. Busch,
B. Hobbs,
A. Litonjua,
D. Sparrow,
A. Gulsvik,
P. Bakke,
J. Crapo,
T. Beaty,
N. Hansel,
R. Mathias,
I. Ruczinski,
K. Barnes,
Y. Bossé,
P. Joubert,
M. Berge,
C. Brandsma,
P. Paré,
D. Sin,
D. Nickle,
K. Hao,
O. Gottesman,
F. Dewey,
S. Bruse,
D. Carey,
H. Kirchner,
Stefan Jonsson,
G. Thorleifsson,
I. Jónsdóttir,
I. Jónsdóttir,
T. Gislason,
K. Stefánsson,
K. Stefánsson,
C. Schurmann,
G. Nadkarni,
E. Bottinger,
R. Loos,
R. Walters,
Zhengming Chen,
I. Millwood,
J. Vaucher,
O. Kurmi,
Liming Li,
Liming Li,
A. Hansell,
C. Brightling,
C. Brightling,
E. Zeggini,
M. Cho,
E. Silverman,
I. Sayers,
G. Trynka,
A. Morris,
D. Strachan,
I. Hall,
M. Tobin,
M. Tobin
|
7 |
2017 |
7
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|
🐜
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Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study
43 auth.
N. Shrine,
M. Portelli,
C. John,
M. Soler Artigas,
N. Bennett,
R. Hall,
J. Lewis,
A. Henry,
C. Billington,
Azaz Ahmad,
R. Packer,
D. Shaw,
Z. Pogson,
A. Fogarty,
T. McKeever,
...
A. Singapuri,
L. Heaney,
A. Mansur,
R. Chaudhuri,
N. Thomson,
J. Holloway,
G. Lockett,
P. Howarth,
R. Djukanović,
J. Hankinson,
R. Niven,
A. Simpson,
K. Chung,
P. Sterk,
J. Blakey,
I. Adcock,
Sile Hu,
Yike Guo,
M. Obeidat,
D. Sin,
M. van den Berge,
D. Nickle,
Y. Bossé,
M. Tobin,
I. Hall,
C. Brightling,
L. Wain,
I. Sayers
|
7 |
2019 |
7
🐜
|
|
🦁
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Genetic risk factors for the development of allergic disease identified by genome-wide association
M. Portelli,
Emily Hodge,
Ian Sayers
|
7 |
2014 |
7
🦁
|
|
🦁
|
Genetic basis for personalized medicine in asthma
M. Portelli,
I. Sayers
|
5 |
2012 |
5
🦁
|
|
🦁
|
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels
14 auth.
M. Portelli,
M. Siedlinski,
C. Stewart,
D. Postma,
M. Nieuwenhuis,
J. Vonk,
P. Nurnberg,
Janine Altmuller,
M. Moffatt,
A. Wardlaw,
...
S. Parker,
M. Connolly,
G. Koppelman,
I. Sayers
|
5 |
2014 |
5
🦁
|
|
🐜
|
Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction
23 auth.
L. Wain,
I. Sayers,
M. Soler Artigas,
M. Portelli,
E. Zeggini,
M. Obeidat,
D. Sin,
Y. Bossé,
D. Nickle,
C. Brandsma,
...
Anders Malarstig,
Ciara Vangjeli,
S. Jelinsky,
Sally John,
I. Kilty,
T. McKeever,
N. Shrine,
J. Cook,
Shrina Patel,
T. Spector,
E. Hollox,
I. Hall,
M. Tobin
|
5 |
2014 |
5
🐜
|
|
🦁
|
Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium
43 auth.
M. Portelli,
F. N. Dijk,
M. Ketelaar,
N. Shrine,
J. Hankinson,
S. Bhaker,
N. Grotenboer,
M. Obeidat,
A. Henry,
C. Billington,
D. Shaw,
S. Johnson,
Z. Pogson,
A. Fogarty,
T. McKeever,
...
D. Nickle,
Y. Bossé,
M. van den Berge,
A. Faiz,
S. Brouwer,
J. Vonk,
P. de Vos,
C. Brandsma,
C. Vermeulen,
A. Singapuri,
L. Heaney,
A. Mansur,
R. Chaudhuri,
N. Thomson,
J. Holloway,
G. Lockett,
P. Howarth,
R. Niven,
A. Simpson,
J. Blakey,
M. Tobin,
D. Postma,
I. Hall,
L. Wain,
M. Nawijn,
C. Brightling,
G. Koppelman,
I. Sayers
|
5 |
2020 |
5
🦁
|
|
🐜
|
Phenotypic and functional translation of IL33 genetics in asthma.
49 auth.
M. Ketelaar,
M. Portelli,
F. N. Dijk,
N. Shrine,
N. Shrine,
A. Faiz,
C. Vermeulen,
Cheng-Jian Xu,
Cheng-Jian Xu,
J. Hankinson,
S. Bhaker,
A. Henry,
Charlote K. Billington,
D. Shaw,
S. Johnson,
...
A. Benest,
V. Pang,
D. O. Bates,
Z. Pogson,
A. Fogarty,
T. McKeever,
A. Singapuri,
L. Heaney,
A. Mansur,
R. Chaudhuri,
N. Thomson,
J. Holloway,
G. Lockett,
P. Howarth,
R. Niven,
A. Simpson,
M. Tobin,
M. Tobin,
I. Hall,
L. Wain,
L. Wain,
J. Blakey,
C. Brightling,
C. Brightling,
M. Obeidat,
D. D. Sin,
D. Nickle,
Y. Bossé,
J. Vonk,
M. Berge,
M. Berge,
G. Koppelman,
I. Sayers,
M. Nawijn
|
4 |
2020 |
4
🐜
|
|
🦁
|
Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients
10 auth.
M. Portelli,
C. Moseley,
C. Stewart,
D. S. Postma,
P. Howarth,
Jane Warner,
...
J. W. Holloway,
G. Koppelman,
Christopher E. Brightling,
Ian Sayers
|
4 |
2017 |
4
🦁
|
