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Partitioning heritability by functional annotation using genome-wide association summary statistics
22 auth.
H. Finucane,
B. Bulik-Sullivan,
A. Gusev,
G. Trynka,
Yakir A. Reshef,
Po-Ru Loh,
V. Anttila,
Han Xu,
C. Zang,
K. Farh,
...
S. Ripke,
F. Day,
S. Purcell,
E. Stahl,
S. Lindstrom,
J. Perry,
Y. Okada,
S. Raychaudhuri,
M. Daly,
N. Patterson,
B. Neale,
A. Price
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11 |
2015 |
11
๐
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|
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|
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
13 auth.
Wei Li,
Han Xu,
T. Xiao,
Le Cong,
Le Cong,
M. Love,
Feng Zhang,
Feng Zhang,
R. Irizarry,
Jun S. Liu,
...
Myles Brown,
Myles A. Brown,
X. Liu
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10 |
2014 |
10
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|
๐
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EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
24 auth.
Kexin Xu,
Z. Wu,
A. Groner,
H. He,
Changmeng Cai,
R. Lis,
R. Lis,
Xiaoqiu Wu,
E. Stack,
E. Stack,
...
M. Loda,
Tao Liu,
Han Xu,
Laura Cato,
J. Thornton,
R. Gregory,
C. Morrissey,
R. Vessella,
R. Montironi,
C. Magi-Galluzzi,
P. Kantoff,
S. Balk,
X. Liu,
Myles A. Brown
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9 |
2012 |
9
๐
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|
๐
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Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
334 auth.
A. Gusev,
S.ย Hong Lee,
G. Trynka,
H. Finucane,
B. Vilhjรกlmsson,
Han Xu,
C. Zang,
S. Ripke,
B. Bulik-Sullivan,
E. Stahl,
A. Kรคhler,
C. Hultman,
S. Purcell,
S. Mccarroll,
M. Daly,
...
B. Pasaniuc,
Patrick F. Sullivan,
B. Neale,
N. Wray,
S. Raychaudhuri,
A. Price,
B. Neale,
A. Corvin,
J. Walters,
Kai-How Farh,
P. Holmans,
Phil H. Lee,
D. A. Collier,
Hailiang Huang,
T. Pers,
I. Agartz,
E. Agerbo,
M. Albus,
Madeline Alexander,
F. Amin,
S. Bacanu,
M. Begemann,
R. Belliveau,
J. Bene,
Sarah E. Bergen,
Elizabeth Bevilacqua,
T. Bigdeli,
D. Black,
A. Bรธrglum,
R. Bruggeman,
N. Buccola,
R. Buckner,
W. Byerley,
W. Cahn,
Guiqing Cai,
D. Campion,
R. Cantor,
Vaughan J. Carr,
N. Carrera,
S. Catts,
K. Chambert,
R. Chan,
Ronald Y. L. Chen,
Eric Y. H. Chen,
Wei Cheng,
E. Cheung,
S. Chong,
C. Cloninger,
David Cohen,
Nadine Cohen,
P. Cormican,
N. Craddock,
J. Crowley,
D. Curtis,
M. Davidson,
Kenneth L. Davis,
F. Degenhardt,
Jurgen Delย Favero,
L. DeLisi,
D. Demontis,
D. Dikeos,
T. Dinan,
S. Djurovic,
G. Donohoe,
Elodie Drapeau,
J. Duan,
F. Dudbridge,
N. Durmishi,
P. Eichhammer,
J. Eriksson,
V. Escott-Price,
L. Essioux,
A. Fanous,
M. Farrell,
J. Frank,
L. Franke,
R. Freedman,
N. Freimer,
M. Friedl,
J. Friedman,
M. Fromer,
G. Genovese,
L. Georgieva,
E. Gershon,
I. Giegling,
Paola Giusti-Rodrguez,
S. Godard,
J. Goldstein,
V. Golimbet,
S. Gopal,
J. Gratten,
J. Grove,
Lieuwe deย Haan,
C. Hammer,
M. Hamshere,
M. Hansen,
T. Hansen,
V. Haroutunian,
A. Hartmann,
F. Henskens,
S. Herms,
J. Hirschhorn,
P. Hoffmann,
A. Hofman,
M. Hollegaard,
D. Hougaard,
M. Ikeda,
I. Joa,
A. Juliร ,
R. Kahn,
L. Kalaydjieva,
Sena Karachanak-Yankova,
J. Karjalainen,
D. Kavanagh,
M. Keller,
B. Kelly,
James L. Kennedy,
A. Khrunin,
Yunjung Kim,
J. Kloviลลก,
J. Knowles,
B. Konte,
V. Kuฤinskas,
Z. Kuฤinskienฤ,
Hana Kuzelova-Ptackova,
A. Kรคhler,
Claudine Laurent,
Jimmy Lee Chee Keong,
S. Legge,
B. Lerer,
Miaoxin Li,
Tao Li,
Kung-Yee Liang,
J. Lieberman,
S. Limborska,
C. Loughland,
J. Lubiลski,
Jouko Lnnqvist,
M. Macek,
P. Magnusson,
B. Maher,
Wolfgang Maier,
J. Mallet,
S. Marsal,
M. Mattheisen,
M. Mattingsdal,
R. McCarley,
C. Mcdonald,
A. McIntosh,
S. Meier,
C. Meijer,
B. Melegh,
I. Melle,
R. Mesholam-Gately,
A. Metspalu,
P. Michie,
L. Milani,
V. Milanova,
Y. Mokrab,
D. Morris,
O. Mors,
P. Mortensen,
Kieran C. Murphy,
Robin M. Murray,
I. MyinโGermeys,
Bertram Mller-Myhsok,
M. Nelis,
I. Nenadiฤ,
D. Nertney,
G. Nestadt,
K. Nicodemus,
L. Nikitina-Zake,
L. Nisenbaum,
Annelie Nordin,
E. O'callaghan,
C. OโDushlaine,
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A. Olincy,
L. Olsen,
Jim Vanย Os,
C. Pantelis,
G. Papadimitriou,
S. Papiol,
E. Parkhomenko,
M. Pato,
T. Paunio,
M. Pejoviฤ-Milovanฤeviฤ,
D. Perkins,
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J. Powell,
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A. Pulver,
S. Purcell,
D. Quested,
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A. Reichenberg,
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V. Salomaa,
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R. Straub,
E. Strengman,
J. Strohmaier,
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M. Subramaniam,
J. Suvisaari,
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H. Ehrenreich,
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S. Mccarroll,
A. McQuillin,
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R. Ophoff,
M. Owen,
A. Palotie,
C. Pato,
T. Petryshen,
D. Posthuma,
M. Rietschel,
B. Riley,
D. Rujescu,
P. Sham,
P. Sklar,
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J. Wendland,
T. Werge,
M. J. Daly,
Patrick F. Sullivan,
M. OโDonovan,
K. Chambert,
J. Moran,
S. Akterin,
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P. Magnusson,
D. Ruderfer,
E. Scolnick,
S. Purcell,
S. Mccarroll
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9 |
2014 |
9
๐
|
|
๐ฆ
|
Sequence determinants of improved CRISPR sgRNA design
16 auth.
Han Xu,
T. Xiao,
Chenhao Chen,
Wei Li,
Clifford A. Meyer,
Qiu Wu,
Qiu Wu,
Diabetes-Ling Wu,
Le Cong,
Le Cong,
...
Feng Zhang,
Feng Zhang,
Jun S. Liu,
Myles A. Brown,
Myles A. Brown,
X. Liu
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9 |
2015 |
9
๐ฆ
|
|
๐
|
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPRโCas9 library
14 auth.
Shiyou Zhu,
Wei Li,
Jingze Liu,
Chenhao Chen,
Qiugang Liao,
Ping Xu,
Han Xu,
T. Xiao,
Zhongzheng Cao,
Jingyu Peng,
...
Pengfei Yuan,
Myles A. Brown,
Xiaole Shirley Liu,
Wensheng Wei
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8 |
2016 |
8
๐
|
|
๐
|
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
8 auth.
Wei Li,
Johannes Kรถster,
Han Xu,
Chenhao Chen,
T. Xiao,
Jun S. Liu,
...
Myles Brown,
X. S. Liu
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8 |
2015 |
8
๐
|
|
๐
|
Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci
8 auth.
G. Trynka,
H. Westra,
Kamil Slowikowski,
Xinli Hu,
Han Xu,
B. Stranger,
...
B. Han,
S. Raychaudhuri
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6 |
2015 |
6
๐
|
|
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|
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline
16 auth.
Qian Qin,
S. Mei,
Qiu Wu,
Hanfei Sun,
Lewyn Li,
Len Taing,
Sujun Chen,
Fugen Li,
Tao Liu,
C. Zang,
...
Han Xu,
Yiwen Chen,
Clifford A. Meyer,
Yong Zhang,
Myles A. Brown,
Henry W. Long
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6 |
2016 |
6
๐
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|
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|
MethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomes
18 auth.
Xiaoqi Zheng,
Qian Zhao,
Hua-Jun Wu,
Wei Li,
Haiyun Wang,
Clifford A. Meyer,
Qian Qin,
Han Xu,
C. Zang,
Peng Jiang,
...
Fuqiang Li,
Yong Hou,
Jianxing He,
Jun Wang,
Jun Wang,
Peng Zhang,
Yong Zhang,
Xiaole Shirley Liu
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6 |
2014 |
6
๐
|
|
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|
Partitioning heritability by functional category using GWAS summary statistics
23 auth.
H. Finucane,
B. Bulik-Sullivan,
A. Gusev,
G. Trynka,
Yakir A. Reshef,
Po-Ru Loh,
Verneri Anttilla,
Han Xu,
C. Zang,
K. Farh,
...
S. Ripke,
F. Day,
ReproGen Consortium,
S. Purcell,
E. Stahl,
S. Lindstrom,
J. Perry,
Y. Okada,
S. Raychaudhuri,
M. Daly,
N. Patterson,
B. Neale,
A. Price
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6 |
2015 |
6
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|
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|
Estrogen-regulated feedback loop limits the efficacy of estrogen receptorโtargeted breast cancer therapy
21 auth.
T. Xiao,
Wei Li,
Xiaoqing Wang,
Han Xu,
Ji-xin Yang,
Qiu Wu,
Ying Huang,
J. Geradts,
Peng Jiang,
Teng Fei,
...
David Chi,
C. Zang,
Qiugang Liao,
J. Rennhack,
E. Andrechek,
Nanlin Li,
S. Detre,
M. Dowsett,
R. Jeselsohn,
X. Liu,
Myles A. Brown
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5 |
2018 |
5
๐
|
