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Yoshitsugu Adachi

Human Molecular Genetics, Cell Reports, Developmental Biology, Brain : a journal of neurology, Proceedings of the National Academy of Sciences of the United States of America, Mechanisms of Development Show more
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Role
Title
Level Year L/R
🐜 Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
20 auth. Youn-bok Lee, Han-Jou Chen, J. Peres, J. Gómez-Deza, J. Attig, M. Štalekar, C. Troakes, A. Nishimura, Emma L. Scotter, C. Vance, ... Yoshitsugu Adachi, V. Sardone, Jack W. Miller, Bradley N. Smith, J. Gallo, J. Ule, F. Hirth, B. Rogelj, C. Houart, C. Shaw 		8 2013
8
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🐜 Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
14 auth. Danielle C. Diaper, Yoshitsugu Adachi, Ben Sutcliffe, Dickon M. Humphrey, C. Elliott, A. Stepto, Zoe N. Ludlow, Lies Vanden Broeck, P. Callaerts, B. Dermaut, ... A. Al-Chalabi, C. Shaw, Iain M. Robinson, F. Hirth 		6 2013
6
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🐜 Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
14 auth. Danielle C. Diaper, Yoshitsugu Adachi, Luke Lazarou, M. Greenstein, F. Simoes, A. di Domenico, D. A. Solomon, Simon A. Lowe, Rawan Alsubaie, Daryl Cheng, ... Stephen Buckley, Dickon M. Humphrey, C. Shaw, F. Hirth 		6 2013
6
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🐜 A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration
24 auth. D. A. Solomon, A. Stepto, Wing Hei Au, Yoshitsugu Adachi, Danielle C. Diaper, Rachel Hall, Anjeet Rekhi, Adel Boudi, Paraskevi Tziortzouda, Youn-bok Lee, ... Bradley N. Smith, Jessika C. Bridi, Greta Spinelli, Jonah Dearlove, Dickon M. Humphrey, J. Gallo, C. Troakes, M. Fanto, M. Soller, B. Rogelj, R. Parsons, C. Shaw, T. Hortobágyi, F. Hirth 		6 2018
6
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🐜 C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
15 auth. Youn-bok Lee, Pranetha Baskaran, J. Gómez-Deza, Han-Jou Chen, A. Nishimura, Bradley N. Smith, C. Troakes, Yoshitsugu Adachi, A. Stepto, L. Petrucelli, ... J. Gallo, F. Hirth, B. Rogelj, S. Guthrie, C. Shaw 		6 2017
6
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🐜 TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila.
14 auth. Lies Vanden Broeck, M. Naval-Sánchez, Yoshitsugu Adachi, Danielle C. Diaper, Pierre Dourlen, J. Chapuis, G. Kleinberger, Marc Gistelinck, C. van Broeckhoven, J. Lambert, ... F. Hirth, S. Aerts, P. Callaerts, B. Dermaut 		5 2013
5
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🐬 A conserved nuclear receptor, Tailless, is required for efficient proliferation and prolonged maintenance of mushroom body progenitors in the Drosophila brain.
Mitsuhiko Kurusu, Y. Maruyama, Yoshitsugu Adachi, M. Okabe, E. Suzuki, K. Furukubo-Tokunaga 		5 2009
5
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🐬 Cross-regulatory protein–protein interactions between Hox and Pax transcription factors
S. Plaza, Frédéric Prince, Yoshitsugu Adachi, Claudio Punzo, D. Cribbs, W. Gehring 		5 2008
5
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🦁 Conserved cis-regulatory modules mediate complex neural expression patterns of the eyeless gene in the Drosophila brain
11 auth. Yoshitsugu Adachi, B. Hauck, J. Clements, H. Kawauchi, Mitsuhiko Kurusu, Yoko Totani, ... Y. Kang, Tanja Eggert, U. Walldorf, K. Furukubo-Tokunaga, P. Callaerts 		5 2003
5
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🐬 Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila.
D. Papadopoulos, Kassiani Skouloudaki, Yoshitsugu Adachi, C. Samakovlis, W. Gehring 		4 2012
4
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