π
|
Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome
20 auth.
J. Habashi,
D. Judge,
Tammy M. Holm,
R. Cohn,
B. Loeys,
T. Cooper,
Loretha A Myers,
E. C. Klein,
Guosheng Liu,
C. Calvi,
...
Megan Podowski,
E. Neptune,
M. Halushka,
D. Bedja,
K. Gabrielson,
D. Rifkin,
L. Carta,
F. Ramirez,
D. Huso,
H. Dietz
|
10 |
2006 |
10 π
|
π
|
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
10 auth.
E. Takimoto,
H. Champion,
Manxiang Li,
Diego Belardi,
Shuxun Ren,
E. Rodriguez,
...
D. Bedja,
K. Gabrielson,
Yibin Wang,
D. Kass
|
9 |
2005 |
9 π
|
π
|
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.
13 auth.
G. Feldmann,
S. Dhara,
V. Fendrich,
D. Bedja,
R. Beaty,
M. Mullendore,
Collins A. Karikari,
H. Alvarez,
C. Iacobuzio-Donahue,
A. Jimeno,
...
K. Gabrielson,
W. Matsui,
A. Maitra
|
9 |
2007 |
9 π
|
π
|
TGF-Ξ²βdependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
11 auth.
C. M. Ng,
A. Cheng,
Loretha A Myers,
F. MartΓnez-Murillo,
C. Jie,
D. Bedja,
...
K. Gabrielson,
J. Hausladen,
R. Mecham,
D. Judge,
H. Dietz
|
8 |
2004 |
8 π
|
π
|
Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism
10 auth.
J. Habashi,
J. Doyle,
Tammy M. Holm,
Hamza Aziz,
F. Schoenhoff,
D. Bedja,
...
Yichun Chen,
Alexandra N. Modiri,
D. Judge,
H. Dietz
|
8 |
2011 |
8 π
|
π
|
Noncanonical TGFΞ² Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice
16 auth.
Tammy M. Holm,
J. Habashi,
J. Doyle,
D. Bedja,
Yichun Chen,
C. van Erp,
M. Lindsay,
David H. Kim,
F. Schoenhoff,
R. Cohn,
...
B. Loeys,
Craig J. Thomas,
S. Patnaik,
J. Marugan,
D. Judge,
H. Dietz
|
8 |
2011 |
8 π
|
π
|
Parkinβindependent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
14 auth.
Y. Kageyama,
M. Hoshijima,
Kinya Seo,
D. Bedja,
Polina Sysa-Shah,
S. Andrabi,
Weiran Chen,
A. HΓΆke,
V. Dawson,
T. Dawson,
...
K. Gabrielson,
D. Kass,
M. Iijima,
H. Sesaki
|
8 |
2014 |
8 π
|
π
|
Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
16 auth.
T. Sussan,
T. Rangasamy,
D. Blake,
D. Malhotra,
H. El-Haddad,
D. Bedja,
M. Yates,
Ponvijay Kombairaju,
Masayuki Yamamoto,
K. Liby,
...
M. Sporn,
K. Gabrielson,
H. Champion,
R. Tuder,
T. Kensler,
S. Biswal
|
8 |
2009 |
8 π
|
π
|
Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease
20 auth.
Dong I. Lee,
Guangshuo Zhu,
Takashi Sasaki,
Gun-sik Cho,
N. Hamdani,
R. Holewinski,
S. Jo,
T. Danner,
Manling Zhang,
P. Rainer,
...
D. Bedja,
Jonathan A. Kirk,
M. Ranek,
W. Dostmann,
Chulan Kwon,
K. Margulies,
J. V. Van Eyk,
W. Paulus,
E. Takimoto,
D. Kass
|
8 |
2015 |
8 π
|
π
|
Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy
10 auth.
G. Baldeviano,
J. Barin,
M. Talor,
S. Srinivasan,
D. Bedja,
D. Zheng,
...
K. Gabrielson,
Y. Iwakura,
N. Rose,
D. ΔihΓ‘kovΓ‘
|
8 |
2010 |
8 π
|
π
|
TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome.
11 auth.
C. M. Ng,
A. Cheng,
Loretha A Myers,
F. MartΓnez-Murillo,
C. Jie,
D. Bedja,
...
K. Gabrielson,
J. Hausladen,
R. Mecham,
D. Judge,
H. Dietz
|
8 |
2004 |
8 π
|
π
|
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer
14 auth.
G. Feldmann,
V. Fendrich,
Karen McGovern,
D. Bedja,
S. Bisht,
H. Alvarez,
Jan-Bart M. Koorstra,
N. Habbe,
Collins A. Karikari,
M. Mullendore,
...
K. Gabrielson,
Rajni B. Sharma,
W. Matsui,
A. Maitra
|
7 |
2008 |
7 π
|