|
π
|
Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells.
11 auth.
T. Hideshima,
H. Ikeda,
D. Chauhan,
Y. Okawa,
N. Raje,
K. Podar,
...
C. Mitsiades,
N. Munshi,
P. Richardson,
Ruben D Carrasco,
K. Anderson
|
8 |
2009 |
8
π
|
|
π¦
|
SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK.
15 auth.
Y. Okawa,
T. Hideshima,
P. Steed,
S. Vallet,
S. Hall,
Ken Huang,
J. Rice,
A. Barabasz,
Brianna Foley,
H. Ikeda,
...
N. Raje,
T. Kiziltepe,
H. Yasui,
S. Enatsu,
K. Anderson
|
7 |
2009 |
7
π¦
|
|
π
|
Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma
11 auth.
I. Breitkreutz,
M. Raab,
S. Vallet,
T. Hideshima,
N. Raje,
C. Mitsiades,
...
D. Chauhan,
Y. Okawa,
N. Munshi,
P. Richardson,
K. Anderson
|
7 |
2008 |
7
π
|
|
π
|
The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD138-Positive Multiple Myeloma Cells In vitro and In vivo
21 auth.
H. Ikeda,
T. Hideshima,
M. Fulciniti,
R. Lutz,
H. Yasui,
Y. Okawa,
T. Kiziltepe,
S. Vallet,
S. Pozzi,
L. Santo,
...
G. Perrone,
Y. Tai,
D. Cirstea,
N. Raje,
C. Uherek,
B. DaΜlken,
S. Aigner,
F. Osterroth,
N. Munshi,
P. Richardson,
K. Anderson
|
7 |
2009 |
7
π
|
|
π
|
5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells
14 auth.
T. Kiziltepe,
T. Hideshima,
L. Catley,
N. Raje,
H. Yasui,
N. Shiraishi,
Y. Okawa,
H. Ikeda,
S. Vallet,
S. Pozzi,
...
K. Ishitsuka,
E. Ocio,
D. Chauhan,
K. Anderson
|
7 |
2007 |
7
π
|
|
π
|
PI3K/p110{delta} is a novel therapeutic target in multiple myeloma.
20 auth.
H. Ikeda,
T. Hideshima,
M. Fulciniti,
G. Perrone,
N. Miura,
H. Yasui,
Y. Okawa,
T. Kiziltepe,
L. Santo,
S. Vallet,
...
D. Cristea,
E. Calabrese,
G. Gorgun,
N. Raje,
P. Richardson,
N. Munshi,
B. Lannutti,
K. Puri,
N. Giese,
K. Anderson
|
7 |
2010 |
7
π
|
|
π
|
MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.
21 auth.
S. Vallet,
N. Raje,
K. Ishitsuka,
T. Hideshima,
K. Podar,
S. Chhetri,
S. Pozzi,
I. Breitkreutz,
T. Kiziltepe,
H. Yasui,
...
E. Ocio,
N. Shiraishi,
J. Jin,
Y. Okawa,
H. Ikeda,
S. Mukherjee,
N. Vaghela,
D. Cirstea,
M. Ladetto,
M. Boccadoro,
K. Anderson
|
7 |
2007 |
7
π
|
|
π
|
AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3Ξ² activation and RNA polymerase II inhibition
19 auth.
L. Santo,
S. Vallet,
T. Hideshima,
D. Cirstea,
Hiroshi Ikeda,
Samantha Pozzi,
K. Patel,
Y. Okawa,
G. Gorgun,
G. Perrone,
...
E. Calabrese,
Murray Yule,
M. Squires,
M. Ladetto,
M. Boccadoro,
P. Richardson,
Nikhil C. Munshi,
K. C. Anderson,
N. Raje
|
6 |
2010 |
6
π
|
|
π
|
Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells
17 auth.
T. Hideshima,
L. Catley,
N. Raje,
D. Chauhan,
K. Podar,
C. Mitsiades,
Y. Tai,
S. Vallet,
T. Kiziltepe,
E. Ocio,
...
H. Ikeda,
Y. Okawa,
Hiromasa Hideshima,
N. Munshi,
H. Yasui,
P. Richardson,
K. Anderson
|
6 |
2007 |
6
π
|
|
π
|
High-Dose Zoledronic Acid Impacts Bone Remodeling with Effects on Osteoblastic Lineage and Bone Mechanical Properties
18 auth.
S. Pozzi,
S. Vallet,
S. Mukherjee,
D. Cirstea,
N. Vaghela,
L. Santo,
Eyal Rosen,
H. Ikeda,
Y. Okawa,
T. Kiziltepe,
...
Jesse A. Schoonmaker,
W. Xie,
T. Hideshima,
E. Weller,
M. Bouxsein,
N. Munshi,
K. Anderson,
N. Raje
|
6 |
2009 |
6
π
|
