๐
|
Pevonedistat (MLN4924), a FirstโinโClass NEDD8โactivating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study
13 auth.
R. Swords,
H. Erba,
D. DeAngelo,
D. Bixby,
J. Altman,
M. Maris,
Zhaowei Hua,
S. Blakemore,
H. Faessel,
F. Sedarati,
...
B. Dezube,
F. Giles,
B. Medeiros
|
7 |
2015 |
7 ๐
|
๐
|
Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, combined with azacitidine in patients with AML.
17 auth.
R. Swords,
S. Coutre,
M. Maris,
J. Zeidner,
J. Foran,
J. Cruz,
H. Erba,
J. Berdeja,
W. Tam,
S. Vardhanabhuti,
...
Iwona Pawlikowska-Dobler,
H. Faessel,
Ajeeta B. Dash,
F. Sedarati,
B. Dezube,
D. Faller,
M. Savona
|
7 |
2018 |
7 ๐
|
๐
|
Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma
16 auth.
J. Shah,
A. Jakubowiak,
O. OโConnor,
R. Orlowski,
D. Harvey,
Mitchell R. Smith,
D. Lebovic,
C. Diefenbach,
K. Kelly,
Zhaowei Hua,
...
A. Berger,
G. Mulligan,
H. Faessel,
S. Tirrell,
B. Dezube,
S. Lonial
|
7 |
2015 |
7 ๐
|
๐ฆ
|
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Varenicline for Smoking Cessation
H. Faessel,
R. Obach,
H. Rollema,
P. Ravva,
K. Williams,
A. Burstein
|
6 |
2010 |
6 ๐ฆ
|
๐ฆ
|
SingleโDose Pharmacokinetics of Varenicline, a Selective Nicotinic Receptor Partial Agonist, in Healthy Smokers and Nonsmokers
H. Faessel,
Bill Smith,
M. Gibbs,
J. Gobey,
D. Clark,
A. Burstein
|
6 |
2006 |
6 ๐ฆ
|
๐
|
A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma
9 auth.
S. Bhatia,
A. Pavlick,
P. Boasberg,
John A Thompson,
G. Mulligan,
M. Pickard,
...
H. Faessel,
B. Dezube,
O. Hamid
|
6 |
2016 |
6 ๐
|
๐ฆ
|
MultipleโDose Pharmacokinetics of the Selective Nicotinic Receptor Partial Agonist, Varenicline, in Healthy Smokers
H. Faessel,
M. Gibbs,
D. Clark,
K. Rohrbacher,
M. Stolar,
A. Burstein
|
6 |
2006 |
6 ๐ฆ
|
๐ฌ
|
The search for cytotoxic synergy between anticancer agents: a case of Dorothy and the ruby slippers?
W. Greco,
H. Faessel,
L. Levasseur
|
6 |
1996 |
6 ๐ฌ
|
๐ข
|
Population pharmacokinetic analysis of varenicline in adult smokers.
P. Ravva,
M. Gastonguay,
T. Tensfeldt,
H. Faessel
|
5 |
2009 |
5 ๐ข
|
๐ฆ
|
Pharmacokinetics, safety, and tolerability of varenicline in healthy adolescent smokers: a multicenter, randomized, double-blind, placebo-controlled, parallel-group study.
H. Faessel,
P. Ravva,
K. Williams
|
5 |
2009 |
5 ๐ฆ
|